Neera Dahl, MD, PhD
Professor AdjunctCards
Additional Titles
Director, Nephrology Clinical Trials Program, Nephrology
Medical Director, Outpatient Dialysis, Nephrology, DaVita New Haven
Contact Info
About
Titles
Professor Adjunct
Director, Nephrology Clinical Trials Program, Nephrology
Positions outside Yale
Medical Director, Outpatient Dialysis, Nephrology, DaVita New Haven
Biography
Dr. Dahl has expertise in diagnosis and management of inherited (or genetically based) kidney disease. Her main focus has been ADPKD and other cystic kidney diseases which mimic ADPKD. She is the medical director of the New Haven DaVita unit providing in center hemodialysis, home hemodialysis and peritoneal dialysis. She is the Director of the Nephrology Clinical Trials program overseeing studies in ADPKD, diabetes and hypertension. In collaboration with Dr. Dinesh Singh she runs the Yale Kidney Stone Clinic.
Appointments
Nephrology
Professor AdjunctPrimary
Other Departments & Organizations
- Chronic Kidney Disease Program
- Internal Medicine
- Nephrology
- Prostate & Urologic Cancers Program
- Yale Cancer Center
- Yale Ventures
Education & Training
- Fellow
- Beth Israel Deaconess Medical Center (2002)
- Resident
- Beth Israel Deaconess Medical Center (1999)
- Intern
- BIDMC, Harvard Medical School (1997)
- PhD
- Tufts University (1996)
- MD
- Tufts University School of Medicine (1996)
- BA
- Johns Hopkins University (1987)
- Postdoctoral, PhD
- Tufts University School of Medicine and Sackler School of Biomedical Science
Research
Overview
In collaboration with Dr. Tinika Montgomery (nephrology), Drs. Dinesh Singh, Piruz Motamedinia, and Tim Tran (urology) we have created a Kidney Stone Registry to track important aspects of kidney stone management.
In the inherited kidney disease space I am most interested in those aspects of clinical research which improve care for ADPKD patients.
Medical Research Interests
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Stefan Somlo, MD
Whitney Besse, MD
Cassius Iyad Ochoa Chaar, MD, MPH, MS, RPVI
Gilbert Moeckel, MD, PhD, FASN
Abinet Aklilu, MD, MPH
Margaret Bia, MD
Kidney Diseases
Nephrology
Publications
2024
Tolvaptan and Autosomal Dominant Polycystic Kidney Disease Progression in Individuals Aged 18–35 Years: A Pooled Database Analysis
Chebib F, Dahl N, Zhou X, Garbinsky D, Wang J, Nunna S, Oberdhan D, Fernandes A. Tolvaptan and Autosomal Dominant Polycystic Kidney Disease Progression in Individuals Aged 18–35 Years: A Pooled Database Analysis. Kidney Medicine 2024, 100935. DOI: 10.1016/j.xkme.2024.100935.Peer-Reviewed Original ResearchConceptsAutosomal dominant polycystic kidney diseaseMedian follow-upEGFR decline rateFollow-upEGFR declineIncreased risk of rapid progressionAutosomal dominant polycystic kidney disease patientsKidney failureRisk of rapid progressionStandard of care treatmentBenefits of tolvaptanTolvaptan-treated patientsChronic kidney disease stageEfficacy of tolvaptanPolycystic kidney disease progressionEffect of tolvaptanAutosomal dominant polycystic kidney disease progressionKidney disease stageDominant polycystic kidney diseaseLong-term efficacyFollow-up periodKidney disease progressionMayo imaging classificationPolycystic kidney diseaseMixed-effects modelsAutosomal Dominant Polycystic Kidney Disease
Suarez M, Titan S, Dahl N. Autosomal Dominant Polycystic Kidney Disease. Advances In Kidney Disease And Health 2024, 31: 496-503. PMID: 39577883, DOI: 10.1053/j.akdh.2024.07.003.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsAutosomal dominant polycystic kidney diseaseDelivery of personalized treatmentKidney diseaseKidney failureMinority of patientsDominant polycystic kidney diseaseEnd-stage kidney diseaseRisk of kidney failureCause of end-stage kidney diseasePolycystic kidney diseaseBlood pressure managementMassive hepatomegalySevere complicationsPolycystic liverIntracranial aneurysmsPersonalized treatmentNatural historyOrgan systemsDiseaseTreatmentKidneyPressure managementLiverSystem conditionsPreimplantationGenetic and Clinical Characterization of Patients with ADPKD and Intracranial Aneurysms: The PKD-VASC Cohort
Patel P, Besse W, Gulati A, Shaw M, Blumenfeld J, Pei Y, Gitomer B, Perrone R, Caliskan Y, Park H, Yu A, Dahl N, Rahbari-Oskoui F, Somlo S, Watnick T. Genetic and Clinical Characterization of Patients with ADPKD and Intracranial Aneurysms: The PKD-VASC Cohort. Journal Of The American Society Of Nephrology 2024, 35: 10.1681/asn.2024pma0ae6c. DOI: 10.1681/asn.2024pma0ae6c.Peer-Reviewed Original ResearchCharacterization of IFT140 Phenotype in Patients with ADPKD Using Advanced Imaging Biomarkers
Ghanem A, Debeh F, Borghol A, Paul S, Alkhatib B, Nader N, Gregory A, Yang H, Hanna C, Dahl N, Kline T, Harris P, Chebib F. Characterization of IFT140 Phenotype in Patients with ADPKD Using Advanced Imaging Biomarkers. Journal Of The American Society Of Nephrology 2024, 35: 10.1681/asn.20240vzj2pha. DOI: 10.1681/asn.20240vzj2pha.Peer-Reviewed Original ResearchKidney Stone Incidence in Patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Ostrow A, Gregory A, Kline T, Harris P, Dahl N, Erickson B, Nowak K, Torres V, Goldfarb D, Gitomer B, Chonchol M. Kidney Stone Incidence in Patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD). Journal Of The American Society Of Nephrology 2024, 35: 10.1681/asn.2024nvt3dy6d. DOI: 10.1681/asn.2024nvt3dy6d.Peer-Reviewed Original ResearchCharacterization of GANAB Phenotype in Patients with ADPKD Using Advanced Imaging Biomarkers
Debeh F, Rangarajan V, Ghanem A, Borghol A, Paul S, Alkhatib B, Nader N, Gregory A, Yang H, Hanna C, Dahl N, Kline T, Harris P, Chebib F. Characterization of GANAB Phenotype in Patients with ADPKD Using Advanced Imaging Biomarkers. Journal Of The American Society Of Nephrology 2024, 35: 10.1681/asn.2024xrre28mc. DOI: 10.1681/asn.2024xrre28mc.Peer-Reviewed Original ResearchCystic Phenotypes Associated with Monoallelic COL4A3/A4/A5 Pathogenic Variants Identified in a Population-Based Cohort
Sohi G, Elbarougy D, Yang H, Schauer R, McDonnell S, Frank J, Ma J, Dahl N, Hogan M, Torres V, Harris P. Cystic Phenotypes Associated with Monoallelic COL4A3/A4/A5 Pathogenic Variants Identified in a Population-Based Cohort. Journal Of The American Society Of Nephrology 2024, 35: 10.1681/asn.202460cgtrgd. DOI: 10.1681/asn.202460cgtrgd.Peer-Reviewed Original ResearchPhenotypic Characterization of Patients with ADPKD with PKD1 and PKD2 Pathogenic Variants Using Advanced Imaging Biomarkers
Borghol A, Debeh F, Ghanem A, Paul S, Alkhatib B, Nader N, Gregory A, Yang H, Hanna C, Dahl N, Kline T, Harris P, Chebib F. Phenotypic Characterization of Patients with ADPKD with PKD1 and PKD2 Pathogenic Variants Using Advanced Imaging Biomarkers. Journal Of The American Society Of Nephrology 2024, 35: 10.1681/asn.2024jkdywd8g. DOI: 10.1681/asn.2024jkdywd8g.Peer-Reviewed Original ResearchClinical Genetic Testing in Nephrology: Core Curriculum 2024
Aron A, Dahl N. Clinical Genetic Testing in Nephrology: Core Curriculum 2024. American Journal Of Kidney Diseases 2024, 84: 632-645. PMID: 39340488, DOI: 10.1053/j.ajkd.2024.05.011.Peer-Reviewed Original ResearchAltmetricConceptsClinical genetic testingGenetic testingRoutine diagnostic workup of patientsKidney diseaseDiagnostic workup of patientsDiagnostic yield of testingRoutine diagnostic workupWorkup of patientsRoutine nephrology careYield of testingGenetic resultsImprove careCore curriculumReduce barriersDiagnostic odysseyExtrarenal manifestationsDiagnostic yieldMonogenic etiologyPatient selectionReduce anxietyPatient populationNephrology careTreatment planningFamily planningSecondary findingsProtein Intake and High Uric Acid Stone Risk
Montgomery T, Nair H, Phadke M, Morhardt E, Ludvigson A, Motamedinia P, Singh D, Dahl N. Protein Intake and High Uric Acid Stone Risk. Kidney Medicine 2024, 6: 100878. PMID: 39279882, PMCID: PMC11399574, DOI: 10.1016/j.xkme.2024.100878.Peer-Reviewed Original ResearchConceptsUric acid stone formersKidney stone formersUric acid stone formationStone formersChronic kidney diseaseStone analysisProtein intakeRetrospective studyKidney functionKidney diseaseAssociated with protein intakeUric acidStone formationLow urine citrateDietary protein intakeDiminished kidney functionProtein catabolic rateBody mass indexUrine urea nitrogenUric acid nephrolithiasisChi-square testPrevalence of uric acid nephrolithiasisUrine citrateNephrology clinicMass index
Clinical Trials
Current Trials
Genetic Determinants of Aneurysms in Autosomal Dominant Polycystic Kidney Disease
HIC ID2000029350RoleSub InvestigatorPrimary Completion Date12/31/2022Recruiting ParticipantsGenderBothAge18+ yearsScreening In Anticipation of Future Research
HIC ID2000021443RoleSub InvestigatorPrimary Completion Date12/31/2022Recruiting ParticipantsGenderBothAge2 years - 17 yearsGenetic Studies of Polycystic Livers
HIC ID0003010983RoleSub InvestigatorPrimary Completion Date04/01/2024Recruiting ParticipantsGenderBothAge18+ years
Academic Achievements & Community Involvement
activity Scientific Advisory Board
Advisory BoardsAdvisorDetailsPKD Foundationinvolved in grant review and patient outreach projects with the PKD Foundation10/01/2018 - Presentactivity Medical Review Board
Advisory BoardsBoard MemberDetailsESRD Network of New EnglandHelped determine focus of the ESRD Network projects10/01/2015 - Presentactivity National Kidney Foundation, CT Chapter
Advisory BoardsBoard MemberDetailsNational Kidney Foundation10/01/2008 - Presentactivity American Journal of Kidney Disease
Journal ServiceReviewerDetails2007 - Presentactivity Clinical Journal of the American Society of Nephrology
Journal ServiceReviewerDetails2007 - Present
News
News
- February 15, 2024
Hybrid Approach to Arteriovenous Fistula Aneurysm Repair
- July 13, 2023
Support System, Consistency Important For Dialysis Patients During Pandemic (Discoveries & Impact July 2023)
- December 19, 2022
Yale Named Center of Excellence by Polycystic Kidney Disease (PKD) Foundation
- November 12, 2022Source: Web MD
Talking to Your Kids About ADPKD