2024
Using a Bayesian analytic approach to identify county-level ecological factors associated with survival among individuals with early-onset colorectal cancer
Siddique S, Baum L, Deziel N, Kelly J, Warren J, Ma X. Using a Bayesian analytic approach to identify county-level ecological factors associated with survival among individuals with early-onset colorectal cancer. PLOS ONE 2024, 19: e0311540. PMID: 39471191, PMCID: PMC11521299, DOI: 10.1371/journal.pone.0311540.Peer-Reviewed Original ResearchConceptsAge-of-onset colorectal cancerEarly-onset colorectal cancerEnd Results Program dataCenters for Disease Control and Prevention dataCounty-level factorsColorectal cancerHealth risk behaviorsIdentified principal componentsOdds of survivalPreventive servicesSurvival disparitiesLinear mixed modelsEOCRCChronic diseasesPreventive factorsUS countiesSalt Lake CountyCA residentsRisk behaviorsUnited StatesProgram dataCounty-levelOlder ageBayesian analytical approachYounger ageHigh ambient temperature in pregnancy and risk of childhood acute lymphoblastic leukaemia: an observational study
Rogne T, Wang R, Wang P, Deziel N, Metayer C, Wiemels J, Chen K, Warren J, Ma X. High ambient temperature in pregnancy and risk of childhood acute lymphoblastic leukaemia: an observational study. The Lancet Planetary Health 2024, 8: e506-e514. PMID: 38969477, PMCID: PMC11260908, DOI: 10.1016/s2542-5196(24)00121-9.Peer-Reviewed Original ResearchConceptsRisk of childhood acute lymphoblastic leukemiaChildhood acute lymphoblastic leukemiaAcute lymphoblastic leukemiaLymphoblastic leukemiaLatino childrenNon-Latino white childrenAssociated with risk of adverse pregnancy outcomesCalifornia Cancer RegistryRisk of acute lymphoblastic leukemiaCalifornia birth recordsRisk of adverse pregnancy outcomesPre-pregnancy periodAssociated with riskBayesian meta-regressionNational Institutes of HealthCancer RegistryCases of childhood acute lymphoblastic leukemiaNational Center for Advancing Translational SciencesAdverse pregnancy outcomesAcute lymphoblastic leukemia casesInstitutes of HealthInvestigation of mechanistic pathwaysBirth recordsGestational weeks 8Pre-pregnancy
2023
Residential proximity to unconventional oil and gas development and birth defects in Ohio
Gaughan C, Sorrentino K, Liew Z, Johnson N, Clark C, Soriano M, Plano J, Plata D, Saiers J, Deziel N. Residential proximity to unconventional oil and gas development and birth defects in Ohio. Environmental Research 2023, 229: 115937. PMID: 37076028, PMCID: PMC10198955, DOI: 10.1016/j.envres.2023.115937.Peer-Reviewed Original ResearchConceptsNeural tube defectsCertain birth defectsBirth defectsOdds ratioRegistry-based cohort studyTube defectsConfidence intervalsResidential proximityState birth recordsBirth defect typeState surveillance systemsMaternal residential proximityLimb reduction defectsCohort studyUnexposed mothersStructural birth defectsLive birthsInfant sexBirth recordsSpina bifidaReduction defectsFemale offspringDevelopmental toxicantsExposure metrics
2022
Urinary phenol concentrations and fecundability and early pregnancy loss
Vollmar A, Weinberg C, Baird D, Wilcox A, Calafat A, Deziel N, Johnson C, Jukic A. Urinary phenol concentrations and fecundability and early pregnancy loss. Human Reproduction 2022, 38: 139-155. PMID: 36346334, PMCID: PMC10089295, DOI: 10.1093/humrep/deac230.Peer-Reviewed Original ResearchConceptsEarly pregnancy lossPregnancy lossUrinary phenol concentrationsIntraclass correlation coefficientMenstrual cycleNational InstituteDaily first-morning urine specimensPhenol exposureEnvironmental Health SciencesFirst morning urine specimensLogistic regressionSTUDY FUNDING/COMPETINGMultivariable logistic regressionPARTICIPANTS/MATERIALSROLE OF CHANCEIntramural Research ProgramClinical miscarriageProspective cohortIncreased oddsLive birthsEpidemiologic studiesUrine specimensHealth SciencesEndocrine-disrupting potentialReproductive functionHemoglobin normalization outperforms other methods for standardizing dried blood spot metabolomics: A comparative study
Jain A, Morris M, Lin EZ, Khan SA, Ma X, Deziel NC, Godri Pollitt KJ, Johnson CH. Hemoglobin normalization outperforms other methods for standardizing dried blood spot metabolomics: A comparative study. The Science Of The Total Environment 2022, 854: 158716. PMID: 36113793, DOI: 10.1016/j.scitotenv.2022.158716.Peer-Reviewed Original ResearchPrenatal Exposure to Per- and Polyfluoroalkyl Substances and Facial Features at 5 Years of Age: A Study from the Danish National Birth Cohort
Luo J, Ramlau-Hansen CH, Kesmodel US, Xiao J, Vasiliou V, Deziel NC, Zhang Y, Olsen J, Liew Z. Prenatal Exposure to Per- and Polyfluoroalkyl Substances and Facial Features at 5 Years of Age: A Study from the Danish National Birth Cohort. Environmental Health Perspectives 2022, 130: 017006. PMID: 35080464, PMCID: PMC8791068, DOI: 10.1289/ehp9478.Peer-Reviewed Original ResearchConceptsDanish National Birth CohortMaternal alcohol intakePrenatal PFAS exposurePalpebral fissure lengthShorter palpebral fissure lengthNational Birth CohortYears of agePFAS exposureSecond tertileAlcohol intakePrenatal exposureOdds ratioBirth cohortSpecific neurologic deficitsConfidence intervalsFetal brain developmentSex-specific associationsNeurologic deficitsFirst trimesterPotential confoundersNeurodevelopmental effectsAlcohol exposureStratified analysisNormal groupMultinomial logistic regression
2020
Birth Characteristics and Risk of Pediatric Thyroid Cancer: A Population-Based Record-Linkage Study in California
Deziel N, Zhang Y, Wang R, Wiemels JL, Morimoto L, Clark CJ, Metayer C, Ma X. Birth Characteristics and Risk of Pediatric Thyroid Cancer: A Population-Based Record-Linkage Study in California. Thyroid 2020, 31: 596-606. PMID: 32912083, PMCID: PMC8195873, DOI: 10.1089/thy.2020.0217.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge of OnsetBirth CertificatesBirth OrderBirth WeightCaliforniaCase-Control StudiesChildChild, PreschoolEducational StatusFemaleHispanic or LatinoHumansIncidenceInfantInfant, NewbornMaleRace FactorsRegistriesRisk AssessmentRisk FactorsSex FactorsThyroid NeoplasmsTime FactorsYoung AdultConceptsPediatric thyroid cancerHigh birth weightFollicular thyroid cancerThyroid cancerHigher birth orderBirth characteristicsRisk factorsHispanic ethnicityBirth weightOdds ratioFirst primary thyroid cancerPapillary thyroid cancer casesBirth orderMultivariable logistic regression modelSecond primary malignanciesLong-term therapyAdjusted odds ratioPopulation-based studyPrimary thyroid cancerRecord linkage studyConfidence intervalsImportant risk factorCancer registry dataCase-control studyThyroid cancer casesZinc Levels and Birth Weight in Pregnant Women with Gestational Diabetes Mellitus: A Matched Cohort Study in China
Luo J, Wu W, Zhang P, Chen X, Feng Y, Ma N, Yang H, Wang Y, Li M, Xie B, Guo P, Liew Z, Deziel NC, Vasiliou V, Shi X, Wang S, Zhang Y. Zinc Levels and Birth Weight in Pregnant Women with Gestational Diabetes Mellitus: A Matched Cohort Study in China. The Journal Of Clinical Endocrinology & Metabolism 2020, 105: dgaa171. PMID: 32285111, DOI: 10.1210/clinem/dgaa171.Peer-Reviewed Original ResearchConceptsGestational diabetes mellitusBirth weightMaternal bloodDiabetes mellitusFetal growthZn intakeMatched Cohort StudyZn levelsDietary Zn intakeCohort studyPregnant womenPlacental transportMultinomial logistic regressionZ-scoreZinc levelsLogistic regressionAdverse effectsWomenMellitusPregnancyLow groupInadequate ZnSuggestive associationAssociationIntakeA Multiregion Analysis of Shale Drilling Activity and Rates of Sexually Transmitted Infections in the United States
Johnson NP, Warren JL, Elliott EG, Niccolai LM, Deziel NC. A Multiregion Analysis of Shale Drilling Activity and Rates of Sexually Transmitted Infections in the United States. Sexually Transmitted Diseases 2020, 47: 254-260. PMID: 32168285, PMCID: PMC7077974, DOI: 10.1097/olq.0000000000001127.Peer-Reviewed Original Research
2019
Genetic susceptibility may modify the association between cell phone use and thyroid cancer: A population-based case-control study in Connecticut
Luo J, Li H, Deziel NC, Huang H, Zhao N, Ma S, Ni X, Udelsman R, Zhang Y. Genetic susceptibility may modify the association between cell phone use and thyroid cancer: A population-based case-control study in Connecticut. Environmental Research 2019, 182: 109013. PMID: 31918310, PMCID: PMC7061309, DOI: 10.1016/j.envres.2019.109013.Peer-Reviewed Original Research
2018
An algorithm for quantitatively estimating non-occupational pesticide exposure intensity for spouses in the Agricultural Health Study
Deziel NC, Beane Freeman LE, Hoppin JA, Thomas K, Lerro CC, Jones RR, Hines CJ, Blair A, Graubard BI, Lubin JH, Sandler DP, Chen H, Andreotti G, Alavanja MC, Friesen MC. An algorithm for quantitatively estimating non-occupational pesticide exposure intensity for spouses in the Agricultural Health Study. Journal Of Exposure Science & Environmental Epidemiology 2018, 29: 344-357. PMID: 30375516, PMCID: PMC6470005, DOI: 10.1038/s41370-018-0088-z.Peer-Reviewed Original ResearchCell phone use and risk of thyroid cancer: a population-based case–control study in Connecticut
Luo J, Deziel NC, Huang H, Chen Y, Ni X, Ma S, Udelsman R, Zhang Y. Cell phone use and risk of thyroid cancer: a population-based case–control study in Connecticut. Annals Of Epidemiology 2018, 29: 39-45. PMID: 30446214, PMCID: PMC6344271, DOI: 10.1016/j.annepidem.2018.10.004.Peer-Reviewed Original ResearchConceptsPopulation-based case-control studyCase-control studyThyroid cancerThyroid microcarcinomaOdds ratioUnconditional logistic regressionPopulation-based controlsThyroid cancer casesWarrants further investigationCancer casesSuggestive increaseElevated riskCell phone useSignificant associationCancerLogistic regressionMicrocarcinomaMore frequent usersConfidence intervalsRiskFrequent usersPhone useFurther investigationAssociationHoursPhthalate Exposure from Drinking Water in Romanian Adolescents
Sulentic RO, Dumitrascu I, Deziel NC, Gurzau AE. Phthalate Exposure from Drinking Water in Romanian Adolescents. International Journal Of Environmental Research And Public Health 2018, 15: 2109. PMID: 30257478, PMCID: PMC6209931, DOI: 10.3390/ijerph15102109.Peer-Reviewed Original ResearchConceptsUrinary phthalate metabolite concentrationsPhthalate metabolite concentrationsChronic low-level exposureAdverse health outcomesLow-level exposureDifferent exposure measuresPhthalate exposurePhthalate metabolitesMunicipal drinking waterUrinary metabolitesHealth outcomesSignificant associationHigher maximum concentrationUrine samplesConsumer product usePotential health risksAdolescent groupExposure sourcesExposure measuresDrinking waterExposure determinantsProduct useMetabolite concentrationsShale gas activity and increased rates of sexually transmitted infections in Ohio, 2000–2016
Deziel NC, Humeau Z, Elliott EG, Warren JL, Niccolai LM. Shale gas activity and increased rates of sexually transmitted infections in Ohio, 2000–2016. PLOS ONE 2018, 13: e0194203. PMID: 29570712, PMCID: PMC5865738, DOI: 10.1371/journal.pone.0194203.Peer-Reviewed Original ResearchConceptsMixed-effects Poisson regression modelsAnnual rate ratiosCases of chlamydiaRate ratioRates of chlamydiaRates of gonorrheaCommunity health effortsPoisson regression modelsPotential confoundersSTI ratesHealth effortsGonorrheaReportable STIsChlamydiaEcologic studySyphilisConfidence intervalsOhio DepartmentInfectionSecular trends
2017
Occupational exposure to pesticides and other biocides and risk of thyroid cancer
Zeng F, Lerro C, Lavoué J, Huang H, Siemiatycki J, Zhao N, Ma S, Deziel NC, Friesen MC, Udelsman R, Zhang Y. Occupational exposure to pesticides and other biocides and risk of thyroid cancer. Occupational And Environmental Medicine 2017, 74: 502. PMID: 28202579, PMCID: PMC5572578, DOI: 10.1136/oemed-2016-103931.Peer-Reviewed Original ResearchConceptsThyroid cancerOccupational exposurePopulation-based case-control studyIncident thyroid cancer casesUnconditional logistic regression modelsCase-control studyPapillary thyroid cancerThyroid cancer casesJob-exposure matrixLogistic regression modelsHigher cumulative probabilityPotential confoundersThyroid microcarcinomaCancer casesHigh riskSignificant associationCancerObserved associationsCumulative probabilityStrong associationRiskAssociationExposureFurther investigationRegression modelsChild, maternal and household-level correlates of nutritional status: a cross-sectional study among young Samoan children
Choy CC, Desai MM, Park JJ, Frame EA, Thompson AA, Naseri T, Reupena MS, Duckham RL, Deziel NC, Hawley NL. Child, maternal and household-level correlates of nutritional status: a cross-sectional study among young Samoan children. Public Health Nutrition 2017, 20: 1235-1247. PMID: 28162141, PMCID: PMC10261405, DOI: 10.1017/s1368980016003499.Peer-Reviewed Original ResearchConceptsOverweight/obesityCross-sectional community-based surveyNutritional statusOdds of anemiaOverweight/obeseCross-sectional studyPrevalence of stuntingCommunity-based surveyCondition-specific interventionsMother-child pairsNutritional status outcomesEarly childhood growthHigher family socio-economic statusAnemic mothersObese childrenSugar intakeSamoan childrenChildhood growthStatus outcomesSocio-economic statusDual burdenAge groupsAnemiaHealth programsGrowth standards
2016
A systematic evaluation of chemicals in hydraulic-fracturing fluids and wastewater for reproductive and developmental toxicity
Elliott EG, Ettinger AS, Leaderer BP, Bracken MB, Deziel NC. A systematic evaluation of chemicals in hydraulic-fracturing fluids and wastewater for reproductive and developmental toxicity. Journal Of Exposure Science & Environmental Epidemiology 2016, 27: 90-99. PMID: 26732376, DOI: 10.1038/jes.2015.81.Peer-Reviewed Original ResearchConceptsWater quality standardsFederal water quality standardsQuality standardsHuman health impactsNatural gas developmentEnvironmental concentrationsHundreds of substancesDevelopmental toxicityReprotox databasesHuman exposureToxicity informationGas developmentExposure assessmentIncorporation of dataHealth StudyHealth impactsSystematic screening approachHydraulic-fracturing fluidsChemical Abstract Service Registry NumbersCandidate analytesChemicalsDrinking waterLikely etiologic agentWastewaterUnconventional oil
2015
Associations between self-reported pest treatments and pesticide concentrations in carpet dust
Deziel NC, Colt JS, Kent EE, Gunier RB, Reynolds P, Booth B, Metayer C, Ward MH. Associations between self-reported pest treatments and pesticide concentrations in carpet dust. Environmental Health 2015, 14: 27. PMID: 25889489, PMCID: PMC4374193, DOI: 10.1186/s12940-015-0015-x.Peer-Reviewed Original ResearchConceptsWeed treatmentsPest treatmentsPesticide concentrationsCarpet dust samplesPesticide active ingredientsAgricultural pesticide applicationsSelf-reported treatmentPesticide useResidential pesticide useTick treatmentPest typesPesticide applicationCypermethrin levelsHerbicide concentrationsPesticide categoriesGarden productsProfessional applicators
2014
Polycyclic aromatic hydrocarbons in residential dust and risk of childhood acute lymphoblastic leukemia
Deziel NC, Rull RP, Colt JS, Reynolds P, Whitehead TP, Gunier RB, Month SR, Taggart DR, Buffler P, Ward MH, Metayer C. Polycyclic aromatic hydrocarbons in residential dust and risk of childhood acute lymphoblastic leukemia. Environmental Research 2014, 133: 388-395. PMID: 24948546, PMCID: PMC4119528, DOI: 10.1016/j.envres.2014.04.033.Peer-Reviewed Original ResearchConceptsAcute lymphoblastic leukemiaChildhood acute lymphoblastic leukemiaLymphoblastic leukemiaOdds ratioPopulation-based case-control studyDiagnosis/reference datePAH exposureRisk of childhoodConfidence intervalsCase-control studyResidential dustVacuum dustLog-transformed concentrationsLogistic regressionProbable human carcinogenHigh volume small surface samplerDemographic characteristicsResidential Levels of Polybrominated Diphenyl Ethers and Risk of Childhood Acute Lymphoblastic Leukemia in California
Ward MH, Colt JS, Deziel NC, Whitehead TP, Reynolds P, Gunier RB, Nishioka M, Dahl GV, Rappaport SM, Buffler PA, Metayer C. Residential Levels of Polybrominated Diphenyl Ethers and Risk of Childhood Acute Lymphoblastic Leukemia in California. Environmental Health Perspectives 2014, 122: 1110-1116. PMID: 24911217, PMCID: PMC4181922, DOI: 10.1289/ehp.1307602.Peer-Reviewed Original ResearchConceptsOdds ratioChildhood acute lymphoblastic leukemiaBirth certificate controlsNorthern California Childhood Leukemia StudyAcute lymphoblastic leukemiaCalifornia Childhood Leukemia StudyYears of ageChildhood Leukemia StudyRace/ethnicityDate of birthLymphoblastic leukemiaLogistic regressionLeukemia StudyAdditional studiesHigh volume small surface samplerBDE-203House dustCommon PBDEsPositive associationBDE-207AssociationBiological measuresRiskBDE-99BDE-196