2024
Uveitis Onset and Flare-Up: Does the Time of Year Matter?
Surapaneni L, Orlofsky P, Kombo N. Uveitis Onset and Flare-Up: Does the Time of Year Matter? Ocular Immunology And Inflammation 2024, 32: 2299-2305. PMID: 38411923, DOI: 10.1080/09273948.2024.2320701.Peer-Reviewed Original ResearchConceptsComorbid autoimmune conditionsUveitis episodeAutoimmune conditionsPosterior uveitisFlare-upHLA-B27Cases of endogenous uveitisHLA-B27 positive patientsIncidence of flare-upsAnatomic location of uveitisDiagnosis of uveitisLocation of uveitisRetrospective chart reviewNon-infectiousTime of onsetIntermediate uveitisUveitis patientsChronic uveitisAnterior uveitisCommunity-based clinicsEndogenous uveitisUveitis onsetPatient agePositive patientsPanuveitis cases
2023
Primary Practice Emphasis Area and Diversity Among Board-Certified Ophthalmologists
Duarte Bojikian K, Mekonnen Z, Adan N, Rivera-Morales P, Kombo N, Feng S. Primary Practice Emphasis Area and Diversity Among Board-Certified Ophthalmologists. American Journal Of Ophthalmology 2023, 260: 84-90. PMID: 38103875, DOI: 10.1016/j.ajo.2023.11.026.Peer-Reviewed Original ResearchConceptsFisher's exact testAmerican Board of OphthalmologyBoard-certified ophthalmologistsRetrospective reviewPacific Islander individualsExact testRegion of practiceOphthalmologistsSelf-reported race/ethnicityOphthalmologyYear of graduationEmphasis areasSelf-identified blacksAmerican BoardAlaska NativesIslander individualsStudent-tStatistical analysisURiMSelf-identifyGlaucomaGender Distribution and Trends of Ophthalmology Subspecialties, 1992-2020
Steren B, Yee P, Rivera P, Feng S, Pepple K, Kombo N. Gender Distribution and Trends of Ophthalmology Subspecialties, 1992-2020. American Journal Of Ophthalmology 2023, 253: 22-28. PMID: 37142172, DOI: 10.1016/j.ajo.2023.04.012.Peer-Reviewed Original ResearchConceptsPrimary practice areaSubspecialty practicePrimary practiceProportion of menPractice areaCross-sectional studyProportion of womenAmerican Board of OphthalmologyYears of certificationBoard-certified ophthalmologistsFisher's exact testOphthalmology subspecialtiesPractice trendsAmerican BoardPractice emphasisSubspecialistsSubspecialtyVitreoretinal surgeryNo significant differenceGender trendsPercentage of malesWomenExact testOphthalmologistsOphthalmology
2020
Ophthalmic Medication Expenditures and Out-of-Pocket Spending An Analysis of United States Prescriptions from 2007 through 2016
Chen EM, Kombo N, Teng CC, Mruthyunjaya P, Nwanyanwu K, Parikh R. Ophthalmic Medication Expenditures and Out-of-Pocket Spending An Analysis of United States Prescriptions from 2007 through 2016. Ophthalmology 2020, 127: 1292-1302. PMID: 32359935, PMCID: PMC7508869, DOI: 10.1016/j.ophtha.2020.04.037.Peer-Reviewed Original ResearchConceptsOphthalmic medicationsMedication expendituresOOP expenditureLongitudinal cohort studyOverall drug expendituresUnited States populationPrescription drug spendingGlaucoma medicationsCohort studyMedication useDry eyePrescription usePrescription expendituresPrescription medicationsOOP expensesMedicationsCopayment assistancePocket expenditureOOP spendingDrug expendituresPocket spendingDrug spendingIndirect costsMEPS participantsLinear regression
2019
Ophthalmic Immune-Related Adverse Events of Immunotherapy: A Single-Site Case Series
Kim J, Materin MA, Sznol M, Kluger H, Weiss S, Chow J, Stoessel K, Kombo N, Del Priore L, Pointdujour-Lim R. Ophthalmic Immune-Related Adverse Events of Immunotherapy: A Single-Site Case Series. Ophthalmology 2019, 126: 1058-1062. PMID: 30735682, PMCID: PMC6933747, DOI: 10.1016/j.ophtha.2019.01.031.Peer-Reviewed Original Research
2017
NEUROSARCOIDOSIS MASQUERADING AS A CENTRAL NERVOUS SYSTEM TUMOR
Elia M, Kombo N, Huang J. NEUROSARCOIDOSIS MASQUERADING AS A CENTRAL NERVOUS SYSTEM TUMOR. Retinal Cases & Brief Reports 2017, 11: s166-s169. PMID: 27571425, DOI: 10.1097/icb.0000000000000402.Peer-Reviewed Original ResearchConceptsOphthalmic examinationOptic nerveHigh-dose oral prednisoneCentral nervous system gliomasCentral nervous system tumorsDiagnosis of neurosarcoidosisIsolated brain lesionOptic nerve infiltrationSerial ophthalmic examinationsRight optic nerveCase of neurosarcoidosisVisual field testingNervous system tumorsLow-grade gliomasMethotrexate weeklyNerve infiltrationOral prednisoneNoncaseating granulomasPrednisone taperNeurologic symptomsOcular sarcoidosisCNS lesionsLeft eyeBrain biopsyFluorescein angiography
2016
The Ex-PRESS Glaucoma Filtration Device Implantation in Uveitic Glaucoma
Dhanireddy S, Kombo NC, Payal AR, Freitas-Neto CA, Preble J, Foster CS. The Ex-PRESS Glaucoma Filtration Device Implantation in Uveitic Glaucoma. Ocular Immunology And Inflammation 2016, 25: 767-774. PMID: 27230295, DOI: 10.1080/09273948.2016.1175639.Peer-Reviewed Original ResearchConceptsIntraocular pressureUveitic glaucomaGlaucoma medicationsGlaucoma patientsSurgical successEx-PRESS implantationUveitic glaucoma patientsMean intraocular pressureEffective surgical interventionPostoperative examinationPreoperative levelsGlaucoma groupPreoperative examinationDevice implantationSurgical interventionUG groupControl groupMedicationsPatientsGlaucomaMean numberMonthsSignificant reductionEyesImplantationDefining the polyposis/colorectal cancer phenotype associated with the Ashkenazi GREM1 duplication: counselling and management recommendations
ZIAI J, MATLOFF E, CHOI J, KOMBO N, MATERIN M, BALE AE. Defining the polyposis/colorectal cancer phenotype associated with the Ashkenazi GREM1 duplication: counselling and management recommendations. Genetics Research 2016, 98: e5. PMID: 26947005, PMCID: PMC6865171, DOI: 10.1017/s0016672316000021.Peer-Reviewed Original ResearchConceptsMixed polyposisExtensive genetic testingComprehensive clinical evaluationColorectal cancer phenotypeCancer phenotypeHereditary colon cancerAutosomal dominant conditionClinical evaluationAshkenazi patientsColon cancer phenotypeColon cancerJuvenile polypsJewish patientsAshkenazi Jewish familiesGenetic testingPolyposisPatientsDominant conditionColon cancer genesPrevious reportsPhenotypeCancer genesManagement recommendations
2015
A Therapeutic Trial of Valganciclovir in Patients with Uveitis and Positive Epstein-Barr virus Early Antigen D IgG Titers
Boonsopon S, Maghsoudlou A, Kombo NE, Foster CS. A Therapeutic Trial of Valganciclovir in Patients with Uveitis and Positive Epstein-Barr virus Early Antigen D IgG Titers. European Journal Of Ophthalmology 2015, 26: 30-35. PMID: 26350994, DOI: 10.5301/ejo.5000673.Peer-Reviewed Original ResearchConceptsPositive Epstein-Barr virusEpstein-Barr virusTherapeutic trialsEBV infection/reactivationInfection/reactivationMassachusetts Eye ResearchCauses of uveitisRetrospective chart reviewImmunoglobulin G titersSurgery institutionsValganciclovir therapyEBV reactivationImmunomodulatory therapyIntraocular inflammationChart reviewIgG titersPersistent inflammationEA antibodyEBV-EAG titersValganciclovirNegative studiesUveitisPatientsInflammation