2019
Sarcomas in the United States: Recent trends and a call for improved staging
Gage MM, Nagarajan N, Ruck JM, Canner JK, Khan S, Giuliano K, Gani F, Wolfgang C, Johnston FM, Ahuja N. Sarcomas in the United States: Recent trends and a call for improved staging. Oncotarget 2019, 10: 2462-2474. PMID: 31069009, PMCID: PMC6497437, DOI: 10.18632/oncotarget.26809.Peer-Reviewed Original ResearchCause-specific mortalityMultivariable logistic regression modelEpidemiology of sarcomasEnd Results (SEER) databaseAppropriate surgical treatmentPatterns of careCases of sarcomaMajority of tumorsStandardization of careLogistic regression modelsCommon histologySurgical treatmentHistologic typeOverall incidenceResults databaseSurgical interventionTrue incidenceImproved stagingSarcoma casesSarcomaPrimary siteComprehensive national studyTreatment factorsHeterogeneous groupTumorsOperative Mortality Prediction for Primary Rectal Cancer: Age Matters
Li Z, Coleman J, D'Adamo CR, Wolf J, Katlic M, Ahuja N, Blumberg D, Ahuja V. Operative Mortality Prediction for Primary Rectal Cancer: Age Matters. Journal Of The American College Of Surgeons 2019, 228: 627-633. PMID: 30630082, DOI: 10.1016/j.jamcollsurg.2018.12.014.Peer-Reviewed Original ResearchConceptsPrimary rectal cancerRectal cancerLogistic regression modelsActual mortalityOlder patientsRisk calculatorAmerican CollegeCovariate-adjusted logistic regression modelsCurrent risk calculatorsICD-9/10 codesColorectal cancer increasesSurgeons NSQIP databaseYears age groupAge categoriesMortality risk estimatesOperative mortalityNSQIP databaseRegression modelsPrognostic valueFunctional statusCancer increasesCare discussionsMortality predictionCPT codesAge groups
2008
Epigenetic Regulation of WNT Signaling Pathway Genes in Inflammatory Bowel Disease (IBD) Associated Neoplasia
Dhir M, Montgomery EA, Glöckner SC, Schuebel KE, Hooker CM, Herman JG, Baylin SB, Gearhart SL, Ahuja N. Epigenetic Regulation of WNT Signaling Pathway Genes in Inflammatory Bowel Disease (IBD) Associated Neoplasia. Journal Of Gastrointestinal Surgery 2008, 12: 1745-1753. PMID: 18716850, PMCID: PMC3976145, DOI: 10.1007/s11605-008-0633-5.Peer-Reviewed Original ResearchConceptsInflammatory Bowel Disease-Associated NeoplasiaIBD colitisNormal colon samplesColorectal cancerLogistic regression modelsAssociated neoplasiaWnt Signaling Pathway GenesMultivariate logistic regression modelPathogenesis of IBDUnivariate logistic regression modelDevelopment of IBDSporadic colorectal cancerProgressive increaseEarly eventsIBD samplesRegression modelsPathway genesCRC samplesColitisNeoplasiaIBDPathway dysregulationColon samplesSignaling Pathway GenesTissue samples