2017
Circulating Epithelial Cells in Intraductal Papillary Mucinous Neoplasms and Cystic Pancreatic Lesions
Poruk KE, Valero V, He J, Ahuja N, Cameron JL, Weiss MJ, Lennon AM, Goggins M, Wood LD, Wolfgang CL. Circulating Epithelial Cells in Intraductal Papillary Mucinous Neoplasms and Cystic Pancreatic Lesions. Pancreas 2017, 46: 943-947. PMID: 28697136, DOI: 10.1097/mpa.0000000000000869.Peer-Reviewed Original ResearchConceptsIntraductal papillary mucinous neoplasmHigh-grade dysplasiaPapillary mucinous neoplasmBlood of patientsEpithelial cellsMucinous neoplasmsPancreatic lesionsAbsence of malignancyBenign pancreatic lesionsCystic pancreatic lesionsNineteen patientsPancreatic resectionPeripheral bloodPancreatic cystsISET methodPatientsPancreas-specific markersResectionMalignancyDysplasiaBloodNeoplasmsPancreatic sourceLow gradeLesions
2015
Intraductal papillary mucinous neoplasm (IPMN) with high-grade dysplasia is a risk factor for the subsequent development of pancreatic ductal adenocarcinoma
Rezaee N, Barbon C, Zaki A, He J, Salman B, Hruban RH, Cameron JL, Herman JM, Ahuja N, Lennon AM, Weiss MJ, Wood LD, Wolfgang CL. Intraductal papillary mucinous neoplasm (IPMN) with high-grade dysplasia is a risk factor for the subsequent development of pancreatic ductal adenocarcinoma. Hepato Pancreato Biliary 2015, 18: 236-246. PMID: 27017163, PMCID: PMC4814593, DOI: 10.1016/j.hpb.2015.10.010.Peer-Reviewed Original ResearchMeSH KeywordsAgedCarcinoma, Pancreatic DuctalDatabases, FactualDisease-Free SurvivalFemaleHumansKaplan-Meier EstimateLymphatic MetastasisMaleMiddle AgedNeoplasm GradingNeoplasm InvasivenessNeoplasms, Cystic, Mucinous, and SerousNeoplasms, Second PrimaryPancreatectomyPancreatic NeoplasmsProportional Hazards ModelsRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeConceptsIntraductal papillary mucinous neoplasmHigh-grade dysplasiaPancreatic ductal adenocarcinomaNon-invasive intraductal papillary mucinous neoplasmsIntermediate-grade dysplasiaPapillary mucinous neoplasmRemnant pancreasVascular invasionMucinous neoplasmsDuctal adenocarcinomaInvasive pancreatic ductal adenocarcinomaMedian overall survivalLymph node metastasisRate of progressionSubsequent developmentIntermediate dysplasiaPancreatic resectionOverall survivalNode metastasisPerineural invasionMalignant entitiesRisk factorsPatientsDysplasiaPancreas
2014
A comparison of open and minimally invasive surgery for hepatic and pancreatic resections using the nationwide inpatient sample
Ejaz A, Sachs T, He J, Spolverato G, Hirose K, Ahuja N, Wolfgang CL, Makary MA, Weiss M, Pawlik TM. A comparison of open and minimally invasive surgery for hepatic and pancreatic resections using the nationwide inpatient sample. Surgery 2014, 156: 538-547. PMID: 25017135, PMCID: PMC4316739, DOI: 10.1016/j.surg.2014.03.046.Peer-Reviewed Original ResearchConceptsMIS patientsInpatient outcomesLiver operationsNationwide Inpatient Sample databasePreoperative medical comorbiditiesIncidence of complicationsMultiple comorbid conditionsShorter median lengthAppropriate International ClassificationNationwide Inpatient SampleInvasive surgery techniquesDuration of stayHospital mortalityPostoperative morbidityHepatic resectionMedical comorbiditiesPancreatic resectionComorbid conditionsMIS groupMedian lengthOpen surgeryInpatient SampleOpen procedureRobotic assistInternational ClassificationA Systematic Review of Solid-Pseudopapillary Neoplasms
Law JK, Ahmed A, Singh VK, Akshintala VS, Olson MT, Raman SP, Ali SZ, Fishman EK, Kamel I, Canto MI, Dal Molin M, Moran RA, Khashab MA, Ahuja N, Goggins M, Hruban RH, Wolfgang CL, Lennon AM. A Systematic Review of Solid-Pseudopapillary Neoplasms. Pancreas 2014, 43: 331-337. PMID: 24622060, PMCID: PMC4888067, DOI: 10.1097/mpa.0000000000000061.Peer-Reviewed Original ResearchConceptsSolid pseudopapillary neoplasmSystematic reviewExcellent long-term prognosisDisease-free survivalMainstay of treatmentMean tumor sizeLong-term prognosisAbdominal painNonspecific symptomsPancreatic resectionMedian timeCommon symptomsNeoplasm casesTumor sizeMean agePatientsNumber of casesYoung womenRecurrenceNeoplasmsSymptomsMonthsTotalPainResectionA Comparison of Open and Minimally Invasive Surgery for Hepatic & Pancreatic Resections Using the Nationwide Inpatient Sample (NIS)
Ejaz A, Sachs T, Spolverato G, Ahuja N, Makary M, Wolfgang C, Hirose K, Weiss M, Pawlik T. A Comparison of Open and Minimally Invasive Surgery for Hepatic & Pancreatic Resections Using the Nationwide Inpatient Sample (NIS). Journal Of Surgical Research 2014, 186: 641-642. DOI: 10.1016/j.jss.2013.11.665.Peer-Reviewed Original Research
2013
Trends and Risk Factors for Transfusion in Hepatopancreatobiliary Surgery
Lucas DJ, Schexneider KI, Weiss M, Wolfgang CL, Frank SM, Hirose K, Ahuja N, Makary M, Cameron JL, Pawlik TM. Trends and Risk Factors for Transfusion in Hepatopancreatobiliary Surgery. Journal Of Gastrointestinal Surgery 2013, 18: 719-728. PMID: 24323432, DOI: 10.1007/s11605-013-2417-9.Peer-Reviewed Original ResearchConceptsRisk of transfusionRisk factorsPerioperative transfusionPreoperative hematocritBlood transfusionHPB proceduresPublic Use FilePatient-level risk factorsAnesthesiologists class IVIncidence of transfusionPerioperative blood transfusionPatient-level factorsHigh-risk factorsPatient-specific factorsHepatopancreatobiliary proceduresTransfusion utilizationPreoperative albuminTransfusion rateASA classificationPancreatic resectionHPB surgeryHepatopancreatobiliary surgeryProcedure typeInclusion criteriaTransfusionIs It Necessary to Follow Patients after Resection of a Benign Pancreatic Intraductal Papillary Mucinous Neoplasm?
He J, Cameron JL, Ahuja N, Makary MA, Hirose K, Choti MA, Schulick RD, Hruban RH, Pawlik TM, Wolfgang CL. Is It Necessary to Follow Patients after Resection of a Benign Pancreatic Intraductal Papillary Mucinous Neoplasm? Journal Of The American College Of Surgeons 2013, 216: 657-665. PMID: 23395158, PMCID: PMC3963007, DOI: 10.1016/j.jamcollsurg.2012.12.026.Peer-Reviewed Original ResearchConceptsIntraductal papillary mucinous neoplasmNoninvasive intraductal papillary mucinous neoplasmsPapillary mucinous neoplasmPancreatic cancerFamily historyMucinous neoplasmsNegative marginsInitial operationPancreatic intraductal papillary mucinous neoplasmsPartial pancreatic resectionMetastatic pancreatic adenocarcinomaInvasive pancreatic cancerRisk of developmentDegree of dysplasiaInitial surgeryMargin statusPancreatic resectionClose surveillanceInvasive adenocarcinomaPancreatic adenocarcinomaResectionPatientsCancerSurgeryAdenocarcinoma
2009
Variations in Referral Patterns to High-Volume Centers for Pancreatic Cancer
Chang DC, Zhang Y, Mukherjee D, Wolfgang CL, Schulick RD, Cameron JL, Ahuja N. Variations in Referral Patterns to High-Volume Centers for Pancreatic Cancer. Journal Of The American College Of Surgeons 2009, 209: 720-726. PMID: 19959040, PMCID: PMC4036485, DOI: 10.1016/j.jamcollsurg.2009.09.011.Peer-Reviewed Original ResearchConceptsHigh-volume centersHigh-volume hospitalsNationwide Inpatient SamplePancreatic cancer patientsArea Resource FilePancreatic resectionCancer patientsInpatient SamplePancreatic cancerRadiation oncologistsCharlson Comorbidity Index scoreComorbidity Index scoreOdds of referralPrimary outcome variableResource FileCommunity poverty levelCalendar yearPatient ageOverall referralsReferral patternsVolume centersInsurance statusPrimary diagnosisInclusion criteriaRetrospective analysis
2008
Pancreatic Resection of Isolated Metastases from Nonpancreatic Primary Cancers
Reddy S, Edil BH, Cameron JL, Pawlik TM, Herman JM, Gilson MM, Campbell KA, Schulick RD, Ahuja N, Wolfgang CL. Pancreatic Resection of Isolated Metastases from Nonpancreatic Primary Cancers. Annals Of Surgical Oncology 2008, 15: 3199-3206. PMID: 18784960, DOI: 10.1245/s10434-008-0140-7.Peer-Reviewed Original ResearchConceptsRenal cell carcinomaPancreatic resectionMetachronous lesionsMetastatic lesionsVascular invasionConclusionLong-term survivalResultsForty-nine patientsLymph node metastasisLangerhans cell histiocytosisDistal pancreatectomyPerioperative deathsPostoperative morbidityTotal pancreatectomyIsolated metastasisMedian survivalMetastatic diseaseSynchronous lesionsNode metastasisPrimary diseasePrimary cancerMedian lengthCell carcinomaGallbladder cancerSingle institutionCell histiocytosisWhat Constitutes a “High-Volume” Hospital for Pancreatic Resection?
Meguid RA, Ahuja N, Chang DC. What Constitutes a “High-Volume” Hospital for Pancreatic Resection? Journal Of The American College Of Surgeons 2008, 206: 622.e1-622.e9. PMID: 18387466, DOI: 10.1016/j.jamcollsurg.2007.11.011.Peer-Reviewed Original ResearchConceptsPancreatic resectionResection volumeCenters of excellenceNationwide Inpatient SampleMultivariable logistic regressionImproved postoperative outcomesHospital mortalityPostoperative mortalityPerioperative deathsPostoperative outcomesInpatient SampleRetrospective analysisResectionVolume thresholdImperfect surrogateLogistic regressionPatients