2017
Postoperative complications following intraoperative radiotherapy in abdominopelvic malignancy: A single institution analysis of 113 consecutive patients
Abdelfatah E, Page A, Sacks J, Pierorazio P, Bivalacqua T, Efron J, Terezakis S, Gearhart S, Fang S, Safar B, Pawlik TM, Armour E, Hacker‐Prietz A, Herman J, Ahuja N. Postoperative complications following intraoperative radiotherapy in abdominopelvic malignancy: A single institution analysis of 113 consecutive patients. Journal Of Surgical Oncology 2017, 115: 883-890. PMID: 28252805, PMCID: PMC5572190, DOI: 10.1002/jso.24597.Peer-Reviewed Original ResearchConceptsExternal beam radiation therapyPostoperative complication rateIntraoperative radiotherapyComplication rateInstitution experienceGrade IIAcceptable perioperative morbidityComplications grade IICurative-intent resectionPostoperative surgical complicationsClavien-Dindo scaleMost common diagnosesMargin-negative resectionSingle-institution analysisJohns Hopkins HospitalBeam radiation therapyAbdominopelvic malignanciesRadiotherapy variablesLocoregional controlPerioperative complicationsPerioperative deathsPerioperative morbidityPostoperative complicationsWound complicationsSurgical complications
2016
Long‐term outcomes in treatment of retroperitoneal sarcomas: A 15 year single‐institution evaluation of prognostic features
Abdelfatah E, Guzzetta AA, Nagarajan N, Wolfgang CL, Pawlik TM, Choti MA, Schulick R, Montgomery EA, Meyer C, Thornton K, Herman J, Terezakis S, Frassica D, Ahuja N. Long‐term outcomes in treatment of retroperitoneal sarcomas: A 15 year single‐institution evaluation of prognostic features. Journal Of Surgical Oncology 2016, 114: 56-64. PMID: 27076350, PMCID: PMC4917421, DOI: 10.1002/jso.24256.Peer-Reviewed Original ResearchConceptsCompartmental resectionRPS patientsSurgical resectionPrognostic factorsR0/R1 marginsR0/R1 resectionEn bloc surgical resectionBloc surgical resectionCornerstone of therapyMainstay of treatmentFive-year survivalRetrospective chart reviewPresence of metastasesEn bloc resectionExtent of resectionConnective tissue tumorsJohns Hopkins HospitalWarrants further investigationR1 resectionRetroperitoneal sarcomaChart reviewMedian survivalR1 marginsDistal recurrenceLocal recurrence
2014
The Impact of Postoperative Complications on the Administration of Adjuvant Therapy Following Pancreaticoduodenectomy for Adenocarcinoma
Wu W, He J, Cameron JL, Makary M, Soares K, Ahuja N, Rezaee N, Herman J, Zheng L, Laheru D, Choti MA, Hruban RH, Pawlik TM, Wolfgang CL, Weiss MJ. The Impact of Postoperative Complications on the Administration of Adjuvant Therapy Following Pancreaticoduodenectomy for Adenocarcinoma. Annals Of Surgical Oncology 2014, 21: 2873-2881. PMID: 24770680, PMCID: PMC4454347, DOI: 10.1245/s10434-014-3722-6.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdultAgedAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsChemotherapy, AdjuvantCombined Modality TherapyFemaleFollow-Up StudiesHumansMaleMiddle AgedNeoplasm StagingPancreatic NeoplasmsPancreaticoduodenectomyPostoperative ComplicationsPrognosisRadiotherapy, AdjuvantRetrospective StudiesSurvival RateConceptsAdjuvant therapyPostoperative complicationsMedian survivalMultivariate analysisClavien-Dindo complication gradeTherapy warrants further investigationMultimodality adjuvant therapyOverall complication rateMethodsA retrospective reviewGrade of complicationsLonger median survivalLength of stayWarrants further investigationAdjuvant chemotherapyMedian TTANeoadjuvant approachComplication gradeComplication rateSevere complicationsRetrospective reviewClinicopathological dataResultsA totalPancreaticoduodenectomyRadiation therapyComplications
2010
Disparity in limb-salvage surgery among sarcoma patients
Downing S, Ahuja N, Oyetunji TA, Chang D, Frederick WA. Disparity in limb-salvage surgery among sarcoma patients. The American Journal Of Surgery 2010, 199: 549-553. PMID: 20359572, DOI: 10.1016/j.amjsurg.2009.12.003.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAmputation, SurgicalAsianBlack or African AmericanFemaleHealth Services AccessibilityHealthcare DisparitiesHispanic or LatinoHumansLimb SalvageLogistic ModelsMaleMiddle AgedMultivariate AnalysisNeoadjuvant TherapyOdds RatioProportional Hazards ModelsRadiotherapy, AdjuvantSarcomaSEER ProgramUnited StatesWhite PeopleConceptsLimb-sparing proceduresLimb salvage surgeryLimb salvagePreoperative radiationSarcoma patientsAfrican AmericansEnd Results (SEER) databaseAfrican American patientsSpecific surgical proceduresWhite patientsResults databaseTreatment modalitiesAmerican patientsSurgical proceduresPatientsMultivariate analysisBivariate analysisLogistic regressionSalvageSurgerySurvivalRecent studiesPrevious studiesTumorsAmericansIs the Debate Finally Over?: Comment on “Survival Effects of Adjuvant Chemoradiation Following Chemoradiotherapy After Resection for Pancreatic Carcinoma”
Ahuja N. Is the Debate Finally Over?: Comment on “Survival Effects of Adjuvant Chemoradiation Following Chemoradiotherapy After Resection for Pancreatic Carcinoma”. JAMA Surgery 2010, 145: 56-56. PMID: 20088100, DOI: 10.1001/archsurg.2009.241.Peer-Reviewed Original Research