Identification of a biomarker panel using a multiplex proximity ligation assay improves accuracy of pancreatic cancer diagnosis
Chang ST, Zahn JM, Horecka J, Kunz PL, Ford JM, Fisher GA, Le QT, Chang DT, Ji H, Koong AC. Identification of a biomarker panel using a multiplex proximity ligation assay improves accuracy of pancreatic cancer diagnosis. Journal Of Translational Medicine 2009, 7: 105. PMID: 20003342, PMCID: PMC2796647, DOI: 10.1186/1479-5876-7-105.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsBiological AssayBiomarkers, TumorHumansPancreatic NeoplasmsProportional Hazards ModelsRegression AnalysisReproducibility of ResultsSensitivity and SpecificityConceptsPancreatic cancer diagnosisCA19-9Pancreatic cancerBiomarker panelProximity ligation assayOptimal biomarker panelCancer diagnosisPancreatic cancer patientsPancreatic ductal adenocarcinoma casesAge-matched controlsLogistic regression modelingCox survival modelsBackgroundPancreatic cancerClinical stagePrognostic significanceMultiplex proximity ligation assayCancer patientsPlasma biomarkersPlasma levelsAdenocarcinoma casesClinical cohortLigation assayDiagnosisCancerBiomarkers