2012
C-MET as a Novel Target for the Treatment of Renal Cell Carcinoma
Vankayala H, LoRusso P, Vaishampayan U. C-MET as a Novel Target for the Treatment of Renal Cell Carcinoma. 2012, 213-238. DOI: 10.1007/978-1-4614-2400-0_10.Peer-Reviewed Original ResearchDysregulation of METHepatocyte growth factor/scatter factorGrowth factor/scatter factorReceptor tyrosine kinasesHGF/SFGenetic programTyrosine kinaseEmbryo developmentPapillary renal carcinomaReceptor familyCell growthScatter factorNovel targetEpithelial cellsC-MetHuman malignanciesSignalingGermline mutationsStructural alterationsMisexpressionEmbryogenesisKinaseMutationsApoptosisRenal carcinoma
2008
First in human phase I study of MK-2461, a small molecule inhibitor of c-Met, for patients with advanced solid tumors
Camacho L, Moulder S, LoRusso P, Blumenschein G, Bristow P, Kurzrock R, Fu S, Schlienger K, Bergstrom D. First in human phase I study of MK-2461, a small molecule inhibitor of c-Met, for patients with advanced solid tumors. Journal Of Clinical Oncology 2008, 26: 14657-14657. DOI: 10.1200/jco.2008.26.15_suppl.14657.Peer-Reviewed Original Research