2004
The Role of Bisphosphonates in the Treatment of Skeletal Complications of Breast Cancer
El-Rayes B, LoRusso P. The Role of Bisphosphonates in the Treatment of Skeletal Complications of Breast Cancer. American Journal Of Cancer 2004, 3: 369-375. DOI: 10.2165/00024669-200403060-00004.Peer-Reviewed Original ResearchBreast cancerZoledronic acidPamidronic acidIbandronic acidPlacebo-controlled trialSerum creatinine levelsSpinal cord compressionLarge randomized studiesMetastatic breast cancerRole of bisphosphonatesBreast cancer patientsClodronic acidClass of agentsCord compressionGastrointestinal symptomsRenal impairmentSkeletal complicationsSkeletal eventsCreatinine levelsMajor toxicityBone destructionBone metastasesRadiographic evidenceRandomized studySignificant morbidity
1998
Controlled‐release oxycodone compared with controlled‐release morphine in the treatment of cancer pain: A randomized, double‐blind, parallel‐group study
Mucci‐LoRusso P, Berman B, Silberstein P, Citron M, Bressler L, Weinstein S, Kaiko R, Buckley B, Reder R. Controlled‐release oxycodone compared with controlled‐release morphine in the treatment of cancer pain: A randomized, double‐blind, parallel‐group study. European Journal Of Pain 1998, 2: 239-249. PMID: 15102384, DOI: 10.1016/s1090-3801(98)90020-9.Peer-Reviewed Original ResearchControlled-release morphineControlled-release oxycodoneCancer-related painVisual analogue scorePlasma concentrationsStable analgesiaPain intensityAdverse experiencesChronic cancer-related painControlled-release oral formulationsSevere cancer-related painSteady-state plasma concentrationsCancer pain patientsDouble-blind treatmentParallel-group studyLess itchingMorphine patientSuitable analgesicCancer painAnalogue scorePain controlSevere painCreatinine levelsTrough fluctuationOral formulation