2021
Cachexia and bladder cancer: clinical impact and management
Lokeshwar SD, Press BH, Nie J, Klaassen Z, Kenney PA, Leapman MS. Cachexia and bladder cancer: clinical impact and management. Current Opinion In Supportive And Palliative Care 2021, 15: 260-265. PMID: 34698663, DOI: 10.1097/spc.0000000000000580.Peer-Reviewed Original ResearchConceptsRadical cystectomyBladder cancerPharmacological agentsManagement of cachexiaNovel pharmaceutical agentsPostoperative complicationsWorse survivalMultidisciplinary managementClinical outcomesHypercatabolic statePalliative carePoor outcomeClinical trialsNutritional supplementationBCa patientsClinical impactPhysical therapyCachexiaRadiation therapyHuman studiesPatientsTherapeutic outcomesNutritional deficienciesNutritional supplementsTumor microenvironmentIncidence, risk factors, and outcome of Clostridioides difficile infection following urological surgeries
Nguyen KA, Le DQ, Bui YT, Advani SD, Renzulli J, Kenney PA, Leapman MS. Incidence, risk factors, and outcome of Clostridioides difficile infection following urological surgeries. World Journal Of Urology 2021, 39: 2995-3003. PMID: 33471163, PMCID: PMC7816064, DOI: 10.1007/s00345-020-03551-y.Peer-Reviewed Original ResearchConceptsNational Surgical Quality Improvement ProgramLength of stayRadical cystectomyUrinary diversionUrological surgeryPostoperative CDIHospital readmissionSurgery typeRisk factorsMultivariable logistic regression analysisSurgical Quality Improvement ProgramPreoperative renal failureRisk of CDISubset of patientsMultivariable logistic regressionIncidence of CDIClostridioides difficile infectionPublic health burdenLogistic regression analysisQuality Improvement ProgramRenal failureSecondary outcomesBlood lossBlood transfusionClinical outcomes
2020
PT414 Similar survival outcomes among chemoradiation and neoadjuvant chemotherapy with radical cystectomy for small cell bladder cancer
Abello A, Renzulli J, Park H, Leapman M, Kenney P. PT414 Similar survival outcomes among chemoradiation and neoadjuvant chemotherapy with radical cystectomy for small cell bladder cancer. European Urology Open Science 2020, 19: e2283. DOI: 10.1016/s2666-1683(20)34148-3.Peer-Reviewed Original Research
2019
Outcomes for urologic oncology procedures: are there differences between academic and community hospitals?
Syed JS, Abello A, Nguyen J, Lee AJH, Desloges JJ, Leapman MS, Kenney PA. Outcomes for urologic oncology procedures: are there differences between academic and community hospitals? World Journal Of Urology 2019, 38: 1187-1193. PMID: 31420696, DOI: 10.1007/s00345-019-02902-8.Peer-Reviewed Original ResearchConceptsLength of stayCommunity hospitalAcademic hospitalReadmission ratesRadical cystectomyHospital-based outcomesDirect costsMean direct costUrologic oncology proceduresStudent's t-testCase mix indexIndex admissionVizient databaseRadical nephroureterectomyPartial cystectomySurgical treatmentUrologic malignanciesOncologic proceduresPartial nephrectomyCystectomyOncology proceduresAcademic centersHospitalProstatectomyStayUrologic malignancies: A comparison of outcomes after index surgery between academic and community hospitals.
Syed J, Abello A, Javier-Desloges J, Leapman M, Kenney P. Urologic malignancies: A comparison of outcomes after index surgery between academic and community hospitals. Journal Of Clinical Oncology 2019, 37: 489-489. DOI: 10.1200/jco.2019.37.7_suppl.489.Peer-Reviewed Original ResearchVizient clinical databaseCase mix indexAcademic hospitalCommunity hospitalRadical prostatectomyReadmission ratesPartial cystectomyRadical cystectomyUrologic malignanciesPartial nephrectomyClinical databaseRate of hospitalDirect costsLength of stayICD-10 codesMean direct costComparison of outcomesPart of treatmentSignificant differencesStudent's t-testIndex admissionIndex surgeryRadical nephroureterectomyPatient demographicsSurgical treatment