2022
Wound Healing Induced Hair Follicle Regeneration
Jiang Y, Myung P. Wound Healing Induced Hair Follicle Regeneration. Stem Cell Biology And Regenerative Medicine 2022, 72: 277-290. DOI: 10.1007/978-3-030-98331-4_13.Peer-Reviewed Original ResearchEmbryonic hair follicle developmentHair follicle developmentHair follicle regenerationHair follicle neogenesisDe novo hair folliclesComplex cellular signalingFollicle regenerationFollicle neogenesisDifferent cellular behaviorsHair follicle formationFollicle developmentLimited regeneration potentialCellular signalingExtrinsic signalsAppendage formationMore mechanistic studiesHair neogenesisCellular behaviorRegenerative woundCrucial playersHair folliclesAdult mammalsRegeneration potentialFollicle formationMammals
2018
Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing
Lim CH, Sun Q, Ratti K, Lee SH, Zheng Y, Takeo M, Lee W, Rabbani P, Plikus MV, Cain JE, Wang DH, Watkins DN, Millar S, Taketo MM, Myung P, Cotsarelis G, Ito M. Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing. Nature Communications 2018, 9: 4903. PMID: 30464171, PMCID: PMC6249328, DOI: 10.1038/s41467-018-07142-9.Peer-Reviewed Original ResearchConceptsSonic hedgehog pathwayMechanisms of scarringHair follicle neogenesisHF neogenesisFibrotic repairScarring woundsMurine skinShh overexpressionWound repairHair follicle regenerationWound healingFollicle neogenesisHedgehog pathwayDermal papillaWnt activationFibrosisWoundsScarringHealingSignal activationNeogenesisActivation resultsMammalian woundsActivationFollicle regeneration