Dissecting Wnt Signaling for Melanocyte Regulation during Wound Healing
Sun Q, Rabbani P, Takeo M, Lee SH, Lim CH, Noel ES, Taketo MM, Myung P, Millar S, Ito M. Dissecting Wnt Signaling for Melanocyte Regulation during Wound Healing. Journal Of Investigative Dermatology 2018, 138: 1591-1600. PMID: 29428355, PMCID: PMC6019608, DOI: 10.1016/j.jid.2018.01.030.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell DifferentiationCicatrixDisease Models, AnimalFemaleHumansIntercellular Signaling Peptides and ProteinsIntracellular Signaling Peptides and ProteinsKeratinocytesMaleMelanocytesMiceMice, TransgenicReceptors, G-Protein-CoupledRegenerationSkinSkin PigmentationStem CellsWnt ProteinsWnt Signaling PathwayWound HealingConceptsMelanocyte stem cellsMelanocyte regenerationEpidermal melanocytesStem cellsWnt ligand secretionActivation of WntWound healingSignal regulationEssential functionsWnt inhibitor Dkk1Wnt ligandsLigand secretionVital regulatorWnt pathwayTransgenic expressionWntMolecular windowΒ-cateninMelanocyte regulationInhibitor DKK1Epithelial cellsMelanocytesWound scarsRegulationAbnormal pigmentation