2017
Cutaneous Fibrosis and Normal Wound Healing
Hamburg-Shields E, Myung P, Cowper S. Cutaneous Fibrosis and Normal Wound Healing. 2017, 577-600. DOI: 10.1007/978-3-319-29785-9_32.ChaptersNumerous cell typesWound healingOrchestrated processEnvironmental perturbationsTranslational mechanismsCell typesExtracellular matrixNormal roleCutaneous wound healingCoordinated productionNormal wound healingCellular playersEnvironmental influencesNormal cutaneous wound healingInjury repairIndividualized functionsMechanismProteinSpecific timeProductionCutaneous fibrosisUnnecessary scarsDisruptionMaintenance
2001
Positive and negative regulation of t-cell activation by adaptor proteins
Koretzky G, Myung P. Positive and negative regulation of t-cell activation by adaptor proteins. Nature Reviews Immunology 2001, 1: 95-107. PMID: 11905825, DOI: 10.1038/35100523.Peer-Reviewed Original ResearchConceptsEffector protein activityPost-translational modificationsSrc family kinasesAdaptor domainsAdaptor proteinSH3 domainFamily kinasesSubcellular localizationGenetic manipulationNegative regulationProtein activityNegative regulatorAdaptorEffector moleculesT cell activationCell linesSpatial organizationRegulatorProteinIntramolecular interactionsLymphocyte activationSH2ActivationKinaseComplexes