In vitro and in vivo macrophage function can occur independently of SLP-76
Myung PS, Clements JL, White DW, Malik ZA, Cowdery JS, Allen LH, Harty JT, Kusner DJ, Koretzky GA. In vitro and in vivo macrophage function can occur independently of SLP-76. International Immunology 2000, 12: 887-897. PMID: 10837416, DOI: 10.1093/intimm/12.6.887.Peer-Reviewed Original ResearchConceptsBone marrow-derived macrophagesFc gamma RWild-type miceGamma RT cellsMacrophage functionStable chronic infectionVivo macrophage functionDownstream mediatorWild-type bone marrow-derived macrophagesFc gamma R ligationCultured bone marrow-derived macrophagesMature T cellsMarrow-derived macrophagesOxygen intermediate productionPlatelet collagen receptorAcute phaseIL-12Chronic infectionMast cellsEffector functionsIFN-gammaPhagocytic functionFc gammaR stimulation