2019
Putting Cell Competition under the Microscope
Levinsohn J, Myung P. Putting Cell Competition under the Microscope. Developmental Cell 2019, 49: 823-824. PMID: 31211989, DOI: 10.1016/j.devcel.2019.05.040.Peer-Reviewed Original Research
2018
Dissecting Wnt Signaling for Melanocyte Regulation during Wound Healing
Sun Q, Rabbani P, Takeo M, Lee SH, Lim CH, Noel ES, Taketo MM, Myung P, Millar S, Ito M. Dissecting Wnt Signaling for Melanocyte Regulation during Wound Healing. Journal Of Investigative Dermatology 2018, 138: 1591-1600. PMID: 29428355, PMCID: PMC6019608, DOI: 10.1016/j.jid.2018.01.030.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell DifferentiationCicatrixDisease Models, AnimalFemaleHumansIntercellular Signaling Peptides and ProteinsIntracellular Signaling Peptides and ProteinsKeratinocytesMaleMelanocytesMiceMice, TransgenicReceptors, G-Protein-CoupledRegenerationSkinSkin PigmentationStem CellsWnt ProteinsWnt Signaling PathwayWound HealingConceptsMelanocyte stem cellsMelanocyte regenerationEpidermal melanocytesStem cellsWnt ligand secretionActivation of WntWound healingSignal regulationEssential functionsWnt inhibitor Dkk1Wnt ligandsLigand secretionVital regulatorWnt pathwayTransgenic expressionWntMolecular windowΒ-cateninMelanocyte regulationInhibitor DKK1Epithelial cellsMelanocytesWound scarsRegulationAbnormal pigmentation
2016
Hardwiring Stem Cell Communication through Tissue Structure
Xin T, Greco V, Myung P. Hardwiring Stem Cell Communication through Tissue Structure. Cell 2016, 164: 1212-1225. PMID: 26967287, PMCID: PMC4805424, DOI: 10.1016/j.cell.2016.02.041.Peer-Reviewed Original Research
2015
Stem Cells Show Parental Control
Myung P, Greco V. Stem Cells Show Parental Control. Cell 2015, 162: 476-477. PMID: 26232219, DOI: 10.1016/j.cell.2015.06.030.Peer-Reviewed Original ResearchNiche-induced cell death and epithelial phagocytosis regulate hair follicle stem cell pool
Mesa KR, Rompolas P, Zito G, Myung P, Sun TY, Brown S, Gonzalez DG, Blagoev KB, Haberman AM, Greco V. Niche-induced cell death and epithelial phagocytosis regulate hair follicle stem cell pool. Nature 2015, 522: 94-97. PMID: 25849774, PMCID: PMC4457634, DOI: 10.1038/nature14306.Peer-Reviewed Original Research
2014
β-Catenin Activation Regulates Tissue Growth Non–Cell Autonomously in the Hair Stem Cell Niche
Deschene ER, Myung P, Rompolas P, Zito G, Sun TY, Taketo MM, Saotome I, Greco V. β-Catenin Activation Regulates Tissue Growth Non–Cell Autonomously in the Hair Stem Cell Niche. Science 2014, 343: 1353-1356. PMID: 24653033, PMCID: PMC4096864, DOI: 10.1126/science.1248373.Peer-Reviewed Original ResearchConceptsWild-type cellsWnt/β-catenin signalingΒ-catenin signalingΒ-catenin activationMouse hair follicle stem cellsΒ-cateninStem cell nicheHair follicle stem cellsFollicle stem cellsNiche signalsMutant cellsCell divisionCell nicheCoordinated regenerationHair growthWnt ligandsCellular displacementCell behaviorStem cellsHair regenerationTissue growthSignalingCellsTissue regenerationActivation
2012
Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration
Myung PS, Takeo M, Ito M, Atit RP. Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration. Journal Of Investigative Dermatology 2012, 133: 31-41. PMID: 22810306, PMCID: PMC3479363, DOI: 10.1038/jid.2012.230.Peer-Reviewed Original ResearchConceptsWnt ligand secretionHair follicle epitheliumFollicle growthHair follicle growthWnt ligandsEpithelial Wnt ligandsHair cycle arrestFollicular epitheliumLigand secretionFollicle epitheliumWnt/β-catenin activationΒ-cateninAnagen inductionWnt/β-cateninStem cell markersΒ-catenin activationPotential cellular targetsHair follicle stem cellsCellular sourceCell markersHair disordersFollicle stem cellsHair folliclesEpitheliumHair follicle regenerationDissecting the bulge in hair regeneration
Myung P, Ito M. Dissecting the bulge in hair regeneration. Journal Of Clinical Investigation 2012, 122: 448-454. PMID: 22293183, PMCID: PMC3266778, DOI: 10.1172/jci57414.Peer-Reviewed Original Research
2011
Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration
Rabbani P, Takeo M, Chou W, Myung P, Bosenberg M, Chin L, Taketo MM, Ito M. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration. Cell 2011, 145: 941-955. PMID: 21663796, PMCID: PMC3962257, DOI: 10.1016/j.cell.2011.05.004.Peer-Reviewed Original ResearchConceptsSecondary hair germMelanocyte stem cellsStem cellsStem cell behaviorStem cell populationHair regenerationHair follicle formationPigment-producing melanocytesHair follicle regenerationHair follicle bulgeEpithelial stem cellsGenetic mouse modelsCoordinated activationWntKey pathwaysCell behaviorWnt activationFollicle bulgeFollicle regenerationComplex organHair germFollicle formationCell populationsMcSCsCells
2009
Defining the hair follicle stem cell (Part II)
Myung P, Andl T, Ito M. Defining the hair follicle stem cell (Part II). Journal Of Cutaneous Pathology 2009, 36: 1134-1137. PMID: 19712246, DOI: 10.1111/j.1600-0560.2009.01412.x.Peer-Reviewed Original ResearchDefining the hair follicle stem cell (Part I)
Myung P, Andl T, Ito M. Defining the hair follicle stem cell (Part I). Journal Of Cutaneous Pathology 2009, 36: 1031-1034. PMID: 19674210, DOI: 10.1111/j.1600-0560.2009.01396.x.Peer-Reviewed Original Research