2020
Extragonadal Yolk Sac Tumor Limited to the Myometrium: Report of a Case With Potential Fertility Preservation and Molecular Analysis Suggesting Germ Cell Origin
Simpson S, Simoni M, Hui P, Taylor H, Buza N. Extragonadal Yolk Sac Tumor Limited to the Myometrium: Report of a Case With Potential Fertility Preservation and Molecular Analysis Suggesting Germ Cell Origin. International Journal Of Gynecological Pathology 2020, 39: 247-253. PMID: 31033797, DOI: 10.1097/pgp.0000000000000601.Peer-Reviewed Original ResearchConceptsYolk sac tumorExtragonadal yolk sac tumorGerm cell originFuture fertilityIntraoperative frozen section evaluationCell originPatient's strong desirePostpubertal female patientsEvidence of diseaseFrozen section evaluationMarked nuclear atypiaClear treatment algorithmRare malignant neoplasmHigh-grade malignancyEosinophilic hyaline globulesNext-generation sequencing resultsAdjuvant chemotherapySurgical stagingAbdominal myomectomyNulligravid womenIrregular bleedingUterine closureWedge resectionYounger patientsFemale patients
2005
Recurrent endometrial stromal tumors with smooth-muscle differentiation and a protracted clinical course
Hui P, Fedoriw G. Recurrent endometrial stromal tumors with smooth-muscle differentiation and a protracted clinical course. Nature Reviews Clinical Oncology 2005, 2: 588-593. PMID: 16270099, DOI: 10.1038/ncponc0340.Peer-Reviewed Original ResearchConceptsEndometrial stromal tumorsSmooth muscle differentiationStromal tumorsPhysical examinationHeavy vaginal bleedingInvestigations Physical examinationPartial wedge resectionAnterior uterine wallTotal abdominal hysterectomySignificant family historyUterine dilationAbdominal hysterectomyAbdominal myomectomyExploratory laparotomyVaginal bleedingAbdominal crampsWedge resectionClinical courseGravida 1Cervical osMedical historyGynecological problemsFamily historyWeeks durationUterine wall