2016
Mucinous epithelial tumours arising from ovarian mature teratomas: a tissue genotyping study
Snir OL, Buza N, Hui P. Mucinous epithelial tumours arising from ovarian mature teratomas: a tissue genotyping study. Histopathology 2016, 69: 383-392. PMID: 26952875, DOI: 10.1111/his.12959.Peer-Reviewed Original ResearchConceptsOvarian mucinous tumorsMucinous borderline tumorsMucinous tumorsBorderline tumorsMucinous carcinomaAssociated teratomaPrimary ovarian mucinous tumorsOvarian mucinous borderline tumorMucinous epithelial tumorsOvarian mature teratomaGerm cell originShort tandem repeat polymorphic lociTissue genotypingMetastatic tumorsMature teratomaEpithelial tumorsTeratomatous componentsTumor originDiagnostic utilityMetastatic onesCell originTumorsTeratomaSomatic cellsPolymorphic loci
2015
Diagnostic application of KRAS mutation testing in uterine microglandular proliferations
Hong W, Abi-Raad R, Alomari AK, Hui P, Buza N. Diagnostic application of KRAS mutation testing in uterine microglandular proliferations. Human Pathology 2015, 46: 1000-1005. PMID: 25997988, DOI: 10.1016/j.humpath.2015.03.010.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdultAgedAged, 80 and overBiopsyCell ProliferationCervix UteriDiagnosis, DifferentialDNA Mutational AnalysisEndometrial HyperplasiaEndometrial NeoplasmsFemaleHumansMiddle AgedMutationPredictive Value of TestsProto-Oncogene ProteinsProto-Oncogene Proteins p21(ras)Ras ProteinsConceptsKRAS mutation analysisEndometrial adenocarcinomaMicroglandular hyperplasiaMicroglandular patternKRAS mutationsCareful morphological assessmentEndometrial mucinous carcinomaKRAS mutation testingCases of EMAMutation analysisFrequent KRAS mutationsElectronic medical recordsDifferential diagnostic toolHigh mitotic activityEndometrial biopsyImmunohistochemical workupUterine cervixMucinous carcinomaClinical historyDiagnostic challengeDiagnostic dilemmaGlandular proliferationMucinous lesionsMedical recordsEAC cases
2013
Frequent KRAS mutation in complex mucinous epithelial lesions of the endometrium
Alomari A, Abi-Raad R, Buza N, Hui P. Frequent KRAS mutation in complex mucinous epithelial lesions of the endometrium. Modern Pathology 2013, 27: 675-680. PMID: 24186144, DOI: 10.1038/modpathol.2013.186.Peer-Reviewed Original ResearchConceptsPositive predictive valueMucinous lesionsKRAS mutationsMucinous changeMucinous adenocarcinomaEndometrial mucinous carcinomaHigh positive predictive valueComplex atypical hyperplasiaRisk stratification algorithmAtypical complex hyperplasiaImportant prognostic indicatorFrequent KRAS mutationsKRAS mutation analysisComplex hyperplasiaHysterectomy specimensClinical progressionEndometrial lesionsMucinous carcinomaAtypical hyperplasiaPrognostic indicatorMucinous differentiationEpithelial lesionsCurettage casesStratification algorithmPredictive value
2010
Endometrial Epithelial Neoplasms
Chhieng D, Hui P. Endometrial Epithelial Neoplasms. Current Clinical Pathology 2010, 87-105. DOI: 10.1007/978-1-60761-164-6_6.Peer-Reviewed Original ResearchCell carcinomaCommon endometrioid adenocarcinomaSquamous cell carcinomaTransitional cell carcinomaClear cell carcinomaHigh-grade carcinomaGestational alterationsEndometrial malignancyCurettage specimenEndometrial hyperplasiaEndometrial polypsEndometrioid adenocarcinomaHistological typeMucinous carcinomaMucinous componentAtypical hyperplasiaEndometrioid carcinomaMixed carcinomasNonneoplastic lesionsPreneoplastic conditionsInflammatory processUndifferentiated carcinomaEpithelial neoplasmsCarcinomaSmall biopsiesSquamous Lesions of the Cervix
Chhieng D, Hui P. Squamous Lesions of the Cervix. Current Clinical Pathology 2010, 35-58. DOI: 10.1007/978-1-60761-164-6_3.Peer-Reviewed Original ResearchSquamous cell carcinomaCell carcinomaHPV infectionHigh-risk HPV infectionCervical intraepithelial neoplasia (CIN) 1Low-risk HPV subtypesLow-risk subtypesHigh-grade CINHigh-risk HPVHuman papillomavirus infectionLow-risk groupClear cell carcinomaMinimal deviation adenocarcinomaSquamous papillomaHPV subtypesPapillomavirus infectionAdenosquamous carcinomaCondyloma acuminatumMucinous carcinomaSerous carcinomaSquamous lesionsCervical adenocarcinomaEndometrioid carcinomaNeuroendocrine carcinomaEndocervical adenocarcinoma