1998
Induction of transporter associated with antigen processing by interferon γ confers endothelial cell cytoprotection against natural killer-mediated lysis
Ayalon O, Hughes E, Cresswell P, Lee J, O’Donnell L, Pardi R, Bender J. Induction of transporter associated with antigen processing by interferon γ confers endothelial cell cytoprotection against natural killer-mediated lysis. Proceedings Of The National Academy Of Sciences Of The United States Of America 1998, 95: 2435-2440. PMID: 9482903, PMCID: PMC19366, DOI: 10.1073/pnas.95.5.2435.Peer-Reviewed Original ResearchConceptsMHC IInduction of transportersEndothelial cellsNK-resistant cell linesNatural killer-mediated lysisMajor histocompatibility complex INK inhibitory receptorsNK effector cellsPretreatment of ECB-lymphoblastoid cell linesEC sensitivityDermal microvascular endothelial cellsMicrovascular endothelial cellsCell linesHuman umbilical vein endothelial cellsExpression/functionUmbilical vein endothelial cellsAdenoviral-mediated transductionVascular vulnerabilityVein endothelial cellsNK assaysEffector cellsEndothelial activationInhibitory receptorsDeficient targets
1989
Adenovirus Inversely Modulates Target Cell Class I Antigen Expression and Sensitivity to Natural Killing
Storkus W, Cresswell P, Patterson E, Dawson J. Adenovirus Inversely Modulates Target Cell Class I Antigen Expression and Sensitivity to Natural Killing. 1989, 152-155. DOI: 10.1007/978-3-662-39946-0_40.Peer-Reviewed Original ResearchAntibody-dependent cellular cytotoxicityComplement-mediated cytolysisNatural killingClass INatural killer cell-mediated cytolysisMajor histocompatibility complex restrictionNK effector cellsI Antigen ExpressionCell-mediated cytolysisMHC class INK sensitiveNK cellsEffector cellsAntigen expressionCellular cytotoxicityViral specificityAdenovirus infectionTarget cellsComplex restrictionCell sensitivityNKRecent evidenceCytolysisCellsKilling
1978
Rabbit antiserum to human B-cell alloantigens II. Mechanism of inhibition of stimulation in the mixed lymphocyte response
Geier S, Cresswell P. Rabbit antiserum to human B-cell alloantigens II. Mechanism of inhibition of stimulation in the mixed lymphocyte response. Cellular Immunology 1978, 35: 392-402. PMID: 145900, DOI: 10.1016/0008-8749(78)90158-2.Peer-Reviewed Original ResearchConceptsAntibody-dependent cell-mediated cytotoxicityMixed lymphocyte responseAnti-B cell serumLymphocyte responsesDependent cell-mediated cytotoxicityInhibition of monocyteHuman B cell alloantigensADCC effector cellsCell-mediated cytotoxicityImmunoglobulin-positive cellsB-cell alloantigensRabbit antiserumEffector cellsMLR suppressionImmune eliminationStimulator cellsPositive cellsLevel of inhibitionMarked reductionCell populationsChicken antiseraAntiserumSimilar specificityMechanism of inhibitionFc region