1998
Clinical and pathologic tumor characteristics of prostate cancer as a function of the number of biopsy cores: a retrospective study
Naughton C, Smith D, Humphrey P, Catalona W, Keetch D. Clinical and pathologic tumor characteristics of prostate cancer as a function of the number of biopsy cores: a retrospective study. Urology 1998, 52: 808-813. PMID: 9801104, DOI: 10.1016/s0090-4295(98)00344-6.Peer-Reviewed Original ResearchConceptsProstate cancerBiopsy coresCore biopsySextant core biopsiesProstate volumeTotal prostate-specific antigen valuesProstate-specific antigen valuesMore biopsy coresMore biopsy sessionsPathologic tumor characteristicsPathologic tumor featuresSix-core biopsyTotal biopsy coresTRUS prostate volumeNegative prostate biopsyClinical prostate cancerMore biopsy samplesProstate cancer detectionPSA densityProspective trialInitial biopsyPathologic characteristicsProstatic volumeSerum tPSATumor characteristics
1995
Morphometric Analysis and Clinical Followup of Isolated Prostatic Intraepithelial Neoplasia in Needle Biopsy of the Prostate
Keetch D, Humphrey P, Stahl D, Smith D, Catalona W. Morphometric Analysis and Clinical Followup of Isolated Prostatic Intraepithelial Neoplasia in Needle Biopsy of the Prostate. Journal Of Urology 1995, 154: 347-351. DOI: 10.1016/s0022-5347(01)67044-7.Peer-Reviewed Original ResearchConceptsProstatic intraepithelial neoplasiaHigh-grade prostatic intraepithelial neoplasiaGrade prostatic intraepithelial neoplasiaSerum PSA concentrationRepeat biopsyIntraepithelial neoplasiaProstate needle biopsyProstate-specific antigenNeedle biopsyInitial biopsyProstate cancerNumber of fociElevated serum PSA concentrationInitial prostate needle biopsyPSA concentrationMen 50 yearsPredictors of cancerDigital rectal examinationInitial biopsy specimenCancer detection rateFinding of cancerSignificance of gradeClinical followupPSA densityPatient ageMorphometric Analysis and Clinical Followup of Isolated Prostatic Intraepithelial Neoplasia in Needle Biopsy of the Prostate
Keetch D, Humphrey P, Stahl D, Smith D, Catalona W. Morphometric Analysis and Clinical Followup of Isolated Prostatic Intraepithelial Neoplasia in Needle Biopsy of the Prostate. Journal Of Urology 1995, 154: 347-351.. PMID: 7541850, DOI: 10.1097/00005392-199508000-00003.Peer-Reviewed Original ResearchConceptsProstatic intraepithelial neoplasiaHigh-grade prostatic intraepithelial neoplasiaGrade prostatic intraepithelial neoplasiaSerum PSA concentrationRepeat biopsyIntraepithelial neoplasiaProstate needle biopsyProstate-specific antigenNeedle biopsyInitial biopsyProstate cancerNumber of fociElevated serum PSA concentrationInitial prostate needle biopsyPSA concentrationMen 50 yearsPredictors of cancerDigital rectal examinationInitial biopsy specimenCancer detection rateFinding of cancerSignificance of gradeClinical followupPSA densityPatient ageRelationship between serum prostate specific antigen, needle biopsy findings, and histopathologic features of prostatic carcinoma in radical prostatectomy tissues
Humphrey P, Baty J, Keetch D. Relationship between serum prostate specific antigen, needle biopsy findings, and histopathologic features of prostatic carcinoma in radical prostatectomy tissues. Cancer 1995, 75: 1842-1849. DOI: 10.1002/1097-0142(19950401)75:7+<1842::aid-cncr2820751614>3.0.co;2-2.Peer-Reviewed Original ResearchSerum prostate-specific antigenProstate-specific antigenPSA densityNeedle biopsy findingsPositive biopsy resultsHistologic gradeNeedle biopsyBiopsy findingsHistopathologic featuresTumor sizeBiopsy resultsProstate cancerPretreatment serum prostate-specific antigenSpecific antigenWhole glandAggressive prostate cancerPercentage of carcinomaRadical prostatectomy specimensRadical prostatectomy tissueWhole prostate glandBiopsy featuresPathologic stageDifferentiated tumorsProstatic carcinomaTumor grade