Distinct host cell fates for human malignant melanoma targeted by oncolytic rodent parvoviruses
Vollmers EM, Tattersall P. Distinct host cell fates for human malignant melanoma targeted by oncolytic rodent parvoviruses. Virology 2013, 446: 37-48. PMID: 24074565, PMCID: PMC3811133, DOI: 10.1016/j.virol.2013.07.013.Peer-Reviewed Original ResearchConceptsPrimary human melanoma cellsPatient-derived melanoma cell linesCurrent therapeutic regimensHuman malignant melanomaRodent parvovirusesHuman melanoma cellsLow response rateMelanoma cell linesOncolytic parvovirusTherapeutic regimensMetastatic melanomaMalignant melanomaResponse rateVirion uptakeViral protein synthesisHost cell fateChimeric virusesMelanoma cellsComplete lysisCell linesMelanomaViral transcriptionParvovirusProgeny virionsLow multiplicity