2009
Epicutaneous Immunization with Protein Antigen in the Presence of TLR4 Ligand Induces TCRαβ+CD4+ T Contrasuppressor Cells That Reverse Skin-Induced Suppression of Th1-Mediated Contact Sensitivity
Ptak W, Majewska M, Bryniarski K, Ptak M, Lobo FM, Zając K, Askenase PW, Szczepanik M. Epicutaneous Immunization with Protein Antigen in the Presence of TLR4 Ligand Induces TCRαβ+CD4+ T Contrasuppressor Cells That Reverse Skin-Induced Suppression of Th1-Mediated Contact Sensitivity. The Journal Of Immunology 2009, 182: 837-850. PMID: 19124727, DOI: 10.4049/jimmunol.182.2.837.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, CutaneousAnimalsCD4-Positive T-LymphocytesCells, CulturedContraindicationsDermatitis, ContactImmune ToleranceImmunizationLigandsLipopolysaccharidesMaleMiceMice, Inbred BALB CMice, Inbred CBAMice, KnockoutMice, TransgenicPatch TestsReceptors, Antigen, T-Cell, alpha-betaSkinTh1 CellsToll-Like Receptor 4TrinitrobenzenesConceptsEpicutaneous immunizationEffector cellsIL-12Effector phaseT cellsIFN-gammaTC cellsContrasuppressor T cellsCS effector cellsIL-12 neutralizationSkin-induced suppressionContact sensitivity reactionTh1 effector cellsTLR4 ligand LPSMechanism of actionEC immunizationSuppressor CD4Th1 CD4Regulatory cellsRIL-12TLR4 ligandIL-6Contact sensitivityLigand LPSINF-gamma
1992
Role of Gamma/Delta T Cells as Positive Regulators of Alpha/Beta TCR+ Effector T Cells in Allergic Contact Sensitivity
Askenase PW, Ptak W. Role of Gamma/Delta T Cells as Positive Regulators of Alpha/Beta TCR+ Effector T Cells in Allergic Contact Sensitivity. International Archives Of Allergy And Immunology 1992, 99: 246-251. PMID: 34167199, DOI: 10.1159/000236258.Peer-Reviewed Original ResearchCutaneous contact sensitivityEffector T cellsCS-effector T cellsT cell receptorΓδ T cellsT cellsCS responsesContact sensitivityGamma/delta T cellsCell transferCS effector cellsDelta T cellsMinor histocompatibility antigensAdoptive cell transferΑβ T cellsAllergic contact sensitivityTCR mAbEffector cellsΓδ TΑβ TAlpha/betaRabbit complementHistocompatibility antigensVitro treatmentCell receptor