2015
Incidence and predictors of post-ERCP pancreatitis in patients with suspected sphincter of Oddi dysfunction undergoing biliary or dual sphincterotomy: results from the EPISOD prospective multicenter randomized sham-controlled study
Yaghoobi M, Pauls Q, Durkalski V, Romagnuolo J, Fogel EL, Tarnasky PR, Aliperti G, Freeman ML, Kozarek RA, Jamidar PA, Wilcox CM, Elta GH, Hawes RH, Wood-Williams A, Cotton PB. Incidence and predictors of post-ERCP pancreatitis in patients with suspected sphincter of Oddi dysfunction undergoing biliary or dual sphincterotomy: results from the EPISOD prospective multicenter randomized sham-controlled study. Endoscopy 2015, 47: 884-890. PMID: 26165739, DOI: 10.1055/s-0034-1392418.Peer-Reviewed Original ResearchMeSH KeywordsAdultCholangiopancreatography, Endoscopic RetrogradeCommon Bile Duct DiseasesFemaleFollow-Up StudiesHumansIncidenceMaleManometryMiddle AgedPancreatitisPostoperative ComplicationsPressurePrognosisProspective StudiesSphincter of OddiSphincter of Oddi DysfunctionSphincterotomy, EndoscopicStentsUnited StatesYoung AdultConceptsPost-ERCP pancreatitisEndoscopic retrograde cholangiopancreatographyDual sphincterotomySedation typeOddi dysfunctionDevelopment of PEPRisk of PEPLife-threatening adverse eventsPancreatic sphincter pressuresPost-cholecystectomy patientsResults of sphincterSOD type IIIProphylactic pancreatic stentsSham-controlled studyEvaluating PredictorsPharmacological prophylaxisERCP pancreatitisProspective multicenterOddi manometryPancreatic stentingSphincter pressureAdverse eventsSham armBiliary sphincterotomyAcute pancreatitis
2014
Effect of Endoscopic Sphincterotomy for Suspected Sphincter of Oddi Dysfunction on Pain-Related Disability Following Cholecystectomy: The EPISOD Randomized Clinical Trial
Cotton PB, Durkalski V, Romagnuolo J, Pauls Q, Fogel E, Tarnasky P, Aliperti G, Freeman M, Kozarek R, Jamidar P, Wilcox M, Serrano J, Brawman-Mintzer O, Elta G, Mauldin P, Thornhill A, Hawes R, Wood-Williams A, Orrell K, Drossman D, Robuck P. Effect of Endoscopic Sphincterotomy for Suspected Sphincter of Oddi Dysfunction on Pain-Related Disability Following Cholecystectomy: The EPISOD Randomized Clinical Trial. JAMA 2014, 311: 2101-2109. PMID: 24867013, PMCID: PMC4428324, DOI: 10.1001/jama.2014.5220.Peer-Reviewed Original ResearchConceptsEndoscopic retrograde cholangiopancreatographySuccessful treatmentDual sphincterotomyAbdominal painOddi dysfunctionEndoscopic sphincterotomyBiliary sphincterotomyObservational study groupPancreatic sphincter hypertensionPancreatic sphincter pressuresReferral medical centerDays of disabilitySuccess of treatmentERCP interventionPancreatic sphincterotomyFinal followPain reliefManometry findingsSphincter pressureSphincterotomy groupManometry resultsNarcotic useRetrograde cholangiopancreatographySham groupClinical trialsCan patient and pain characteristics predict manometric sphincter of Oddi dysfunction in patients with clinically suspected sphincter of Oddi dysfunction?
Romagnuolo J, Cotton PB, Durkalski V, Pauls Q, Brawman-Mintzer O, Drossman DA, Mauldin P, Orrell K, Williams AW, Fogel EL, Tarnasky PR, Aliperti G, Freeman ML, Kozarek RA, Jamidar PA, Wilcox CM, Serrano J, Elta GH. Can patient and pain characteristics predict manometric sphincter of Oddi dysfunction in patients with clinically suspected sphincter of Oddi dysfunction? Gastrointestinal Endoscopy 2014, 79: 765-772. PMID: 24472759, PMCID: PMC4409681, DOI: 10.1016/j.gie.2013.11.037.Peer-Reviewed Original ResearchMeSH KeywordsAbdominal PainAdultAnalgesics, OpioidAnxietyCholangiopancreatography, Endoscopic RetrogradeCholecystectomyCross-Sectional StudiesDepressionFemaleHumansMaleManometryMiddle AgedPostoperative PeriodPredictive Value of TestsProspective StudiesPsychiatric Status Rating ScalesSphincter of Oddi DysfunctionConceptsRight upper quadrantOddi dysfunctionFunctional disordersOddi dysfunction (SOD) type IIIType III SODLiver enzyme abnormalitiesAbnormal sphincterPostcholecystectomy painPain characteristicsPain patternsAbdominal discomfortClinical characteristicsOddi manometryClinical factorsClinical predictorsUpper quadrantGallbladder pathologyMean agePsychological comorbiditiesUnderwent ERCPPain factorsSignificant abnormalitiesEnzyme abnormalitiesUnnecessary ERCPExperienced depressionPsychosocial Characteristics and Pain Burden of Patients With Suspected Sphincter of Oddi Dysfunction in the EPISOD Multicenter Trial
Brawman-Mintzer O, Durkalski V, Wu Q, Romagnuolo J, Fogel E, Tarnasky P, Aliperti G, Freeman M, Kozarek R, Jamidar P, Wilcox M, Elta G, Orrell K, Wood A, Mauldin P, Serrano J, Drossman D, Robuck P, Cotton P. Psychosocial Characteristics and Pain Burden of Patients With Suspected Sphincter of Oddi Dysfunction in the EPISOD Multicenter Trial. The American Journal Of Gastroenterology 2014, 109: 436. PMID: 24445573, PMCID: PMC4409683, DOI: 10.1038/ajg.2013.467.Peer-Reviewed Original ResearchConceptsFunctional gastrointestinal disordersPain burdenOddi dysfunctionGender-matched general populationPainful functional gastrointestinal disordersFunctional gallbladder diseaseGreater pain burdenPost-cholecystectomy painHealth-related qualityMental composite scoreAnxiety/depressionBaseline anxiety scoresPsychosocial comorbiditiesMulticenter trialIrritable bowelGastrointestinal disordersGallbladder diseasePain descriptorsPsychosocial assessmentHigh prevalencePsychosocial parametersUS CentersStudy populationPsychosocial disturbancesSevere psychological problems
2006
Pharmacologic prevention of post-ERCP pancreatitis: is nitroglycerin a sangreal?
Muralidharan V, Jamidar P. Pharmacologic prevention of post-ERCP pancreatitis: is nitroglycerin a sangreal? Gastrointestinal Endoscopy 2006, 64: 358-360. PMID: 16923482, DOI: 10.1016/j.gie.2005.12.027.Peer-Reviewed Original Research