Percutaneous transhepatic vs. endoscopic retrograde biliary drainage for suspected malignant hilar obstruction: study protocol for a randomized controlled trial
Al-Kawas F, Aslanian H, Baillie J, Banovac F, Buscaglia JM, Buxbaum J, Chak A, Chong B, Coté GA, Draganov PV, Dua K, Durkalski V, Elmunzer BJ, Foster LD, Gardner TB, Geller BS, Jamidar P, Jamil LH, Keswani RN, Khashab MA, Lang GD, Law R, Lichtenstein D, Lo SK, McCarthy S, Melo S, Mullady D, Nieto J, Bayne Selby J, Singh VK, Spitzer RL, Strife B, Tarnaksy P, Taylor JR, Tokar J, Wang AY, Williams A, Willingham F, Yachimski P, In alphabetical order for the INTERCPT Study Group and the United States Cooperative for Outcomes Research in Endoscopy (USCORE). Percutaneous transhepatic vs. endoscopic retrograde biliary drainage for suspected malignant hilar obstruction: study protocol for a randomized controlled trial. Trials 2018, 19: 108. PMID: 29444707, PMCID: PMC5813390, DOI: 10.1186/s13063-018-2473-2.Peer-Reviewed Original ResearchMeSH KeywordsBile Duct NeoplasmsCholangiopancreatography, Endoscopic RetrogradeCholestasisComparative Effectiveness ResearchDrainageEquivalence Trials as TopicHumansMulticenter Studies as TopicTime FactorsTreatment OutcomeUnited StatesConceptsPercutaneous transhepatic biliary drainageEndoscopic retrograde cholangiographyMalignant hilar obstructionBiliary drainageHilar obstructionEndoscopic retrograde biliary drainageAdequate tissue diagnosisSuccessful biliary drainageTranshepatic biliary drainageCommon clinical dilemmaUsual clinical careSubsequent clinical interventionsBest initial approachEligible patientsOncological outcomesAdverse eventsLiver hilumOutcome assessorsMalignant obstructionRetrograde cholangiographySuperiority trialEnrolled subjectsClinical dilemmaTissue diagnosisMedical Center