2018
The Clinical Significance of Breast-only and Node-only Pathologic Complete Response (pCR) After Neoadjuvant Chemotherapy (NACT)
Fayanju O, Ren Y, Thomas S, Greenup R, Plichta J, Rosenberger L, Tamirisa N, Force J, Boughey J, Hyslop T, Hwang E. The Clinical Significance of Breast-only and Node-only Pathologic Complete Response (pCR) After Neoadjuvant Chemotherapy (NACT). Annals Of Surgery 2018, 268: 591-601. PMID: 30048319, PMCID: PMC6496955, DOI: 10.1097/sla.0000000000002953.Peer-Reviewed Original ResearchConceptsPathologic complete responseImproved overall survivalNeoadjuvant chemotherapyOverall survivalComplete responseBreast cancerHuman epidermal growth factor receptor 2 (HER2) statusEpidermal growth factor receptor 2 statusCox proportional hazards modelHormone receptorsNode-positive patientsTriple-negative diseaseKaplan-Meier curvesBreast cancer patientsMultivariate logistic regressionProportional hazards modelAnatomic extentCancer patientsReceptor subtypesClinical significanceHazards modelTumor subtypesPatientsBreastLogistic regressionAxillary Nodal Evaluation in Elderly Breast Cancer Patients: Potential Effects on Treatment Decisions and Survival
Tamirisa N, Thomas S, Fayanju O, Greenup R, Rosenberger L, Hyslop T, Hwang E, Plichta J. Axillary Nodal Evaluation in Elderly Breast Cancer Patients: Potential Effects on Treatment Decisions and Survival. Annals Of Surgical Oncology 2018, 25: 2890-2898. PMID: 29968029, PMCID: PMC6404232, DOI: 10.1245/s10434-018-6595-2.Peer-Reviewed Original ResearchConceptsBreast cancer patientsElderly breast cancer patientsCN0 breast cancerOverall survivalNodal surgeryCancer patientsAxillary surgeryElderly patientsTreatment decisionsBreast cancerCharlson-Deyo comorbidity scoreCN0 breast cancer patientsSurgical lymph node evaluationCox proportional hazards modelAdjuvant therapy decisionsAdjuvant therapy receiptAxillary nodal evaluationLymph node evaluationNational Cancer DatabaseYear of diagnosisWorse overall survivalEstrogen receptor statusLong-term outcomesSubsequent treatment decisionsProportional hazards model
2012
Application of ACOSOG Z0011 Criteria Reduces Perioperative Costs
Camp M, Greenup R, Taghian A, Coopey S, Specht M, Gadd M, Hughes K, Smith B. Application of ACOSOG Z0011 Criteria Reduces Perioperative Costs. Annals Of Surgical Oncology 2012, 20: 836-841. PMID: 23010735, DOI: 10.1245/s10434-012-2664-0.Peer-Reviewed Original ResearchMeSH KeywordsAxillaBreast NeoplasmsCombined Modality TherapyCost-Benefit AnalysisFemaleFollow-Up StudiesHumansLymph Node ExcisionLymphatic MetastasisMastectomy, SegmentalNeoplasm Recurrence, LocalNeoplasm StagingPractice Guidelines as TopicPrognosisRetrospective StudiesSentinel Lymph Node BiopsySurvival RateConceptsAxillary lymph node dissectionCompletion axillary lymph node dissectionPerioperative surgical managementOvernight admissionPerioperative costsZ0011 criteriaSurgical managementBreast cancerSentinel lymph node-positive breast cancerLymph node-positive breast cancerNode-positive breast cancerACOSOG Z0011 criteriaACOSOG Z0011 trialOvernight hospital admissionLymph node dissectionRetrospective chart reviewInvasive breast cancerBreast conservation therapyInpatient hospital daysPositive breast cancerExcellent regional controlPositive SLNZ0011 trialEligible patientsNode dissection