2017
Miniature spectral imaging device for wide-field quantitative functional imaging of the morphological landscape of breast tumor margins
Nichols B, Llopis A, Palmer G, McCachren S, Senlik O, Miller D, Brooke M, Jokerst N, Geradts J, Greenup R, Ramanujam N. Miniature spectral imaging device for wide-field quantitative functional imaging of the morphological landscape of breast tumor margins. Journal Of Biomedical Optics 2017, 22: 026007-026007. PMID: 28241273, PMCID: PMC5321165, DOI: 10.1117/1.jbo.22.2.026007.Peer-Reviewed Original ResearchMeSH KeywordsBreast NeoplasmsFemaleHumansMastectomy, SegmentalMiniaturizationMonte Carlo MethodSpectrum AnalysisConceptsBreast tumor marginsDiffuse optical spectroscopyVisible spectral rangeSpectral imaging deviceDiffuse reflectance spectraOptical spectroscopySpectral rangeImaging arrayMorphological landscapeRaster scanningOptical surrogatesImaging devicesQuantitative functional imagingReflectance spectraImaging platformImaging probeMonte CarloCompressive sensingInverse modelContent ratioWavelengthProbeFunctional imagingSpectroscopySpectra
2015
Trends in Treatment Patterns and Outcomes for Ductal Carcinoma in Situ
Worni M, Akushevich I, Greenup R, Sarma D, Ryser M, Myers E, Hwang E. Trends in Treatment Patterns and Outcomes for Ductal Carcinoma in Situ. Journal Of The National Cancer Institute 2015, 107: djv263. PMID: 26424776, PMCID: PMC4707192, DOI: 10.1093/jnci/djv263.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBiomarkers, TumorBreast NeoplasmsCarcinoma, Intraductal, NoninfiltratingConfounding Factors, EpidemiologicDisease-Free SurvivalFemaleHumansMastectomyMastectomy, Modified RadicalMastectomy, SegmentalMiddle AgedNeoplasm GradingNeoplasm StagingOdds RatioProportional Hazards ModelsRadiotherapy, AdjuvantReceptors, EstrogenReceptors, ProgesteroneSEER ProgramSentinel Lymph Node BiopsySurvival AnalysisTreatment OutcomeUnited StatesConceptsOverall survivalTreatment patternsPre-invasive breast cancerSentinel lymph node biopsyCox proportional hazards regressionLocoregional treatment optionsNational treatment trendsEnd Results registryLymph node biopsyBreast cancer outcomesLong-term outcomesProportional hazards regressionPatient selection biasCochran-Armitage trend testInverse probability weightsDCIS patientsNode biopsyBilateral mastectomyDuctal carcinomaHazards regressionCancer outcomesTreatment optionsBreast cancerTreatment trendsLumpectomyA Quantitative Diffuse Reflectance Imaging (QDRI) System for Comprehensive Surveillance of the Morphological Landscape in Breast Tumor Margins
Nichols B, Schindler C, Brown J, Wilke L, Mulvey C, Krieger M, Gallagher J, Geradts J, Greenup R, Von Windheim J, Ramanujam N. A Quantitative Diffuse Reflectance Imaging (QDRI) System for Comprehensive Surveillance of the Morphological Landscape in Breast Tumor Margins. PLOS ONE 2015, 10: e0127525. PMID: 26076123, PMCID: PMC4468201, DOI: 10.1371/journal.pone.0127525.Peer-Reviewed Original ResearchConceptsBreast tumor marginsOptical property mapsDiffuse optical spectroscopyImaging systemWhite LED sourceDiffuse reflectance imagesOptical spectroscopyDistribution function analysisFiber optic probeTurbid mediaEmpirical cumulative distribution function (eCDF) analysisLarge tissue areasLED sourcesScattering coefficientSub-pixel resolutionProbe-tissue interfaceIntra-operative toolMorphological landscapeOptic probeImaging platformTime scalesProperty mapsImproved sensitivityEstimation errorSpectrograph
2014
Management of Positive Sub‐areolar/Nipple Duct Margins in Nipple‐Sparing Mastectomies
Camp M, Coopey S, Tang R, Colwell A, Specht M, Greenup R, Gadd M, Brachtel E, Austen W, Smith B. Management of Positive Sub‐areolar/Nipple Duct Margins in Nipple‐Sparing Mastectomies. The Breast Journal 2014, 20: 402-407. PMID: 24890641, DOI: 10.1111/tbj.12279.Peer-Reviewed Original ResearchConceptsNipple-sparing mastectomyNipple-areola complexPositive marginsNAC specimensCancer-bearing breastsResidual invasive cancerRetrospective chart reviewInvasive lobular carcinomaResidual DCISChart reviewResidual malignancyDuctal carcinomaInvasive cancerLobular carcinomaProphylactic mastectomyDuctal tissueAreola complexTreatment informationMastectomyCarcinomaTissue removalNippleFuture studiesDCISMalignancyCost Implications of the SSO-ASTRO Consensus Guideline on Margins for Breast-Conserving Surgery with Whole Breast Irradiation in Stage I and II Invasive Breast Cancer
Greenup R, Peppercorn J, Worni M, Hwang E. Cost Implications of the SSO-ASTRO Consensus Guideline on Margins for Breast-Conserving Surgery with Whole Breast Irradiation in Stage I and II Invasive Breast Cancer. Annals Of Surgical Oncology 2014, 21: 1512-1514. PMID: 24577813, DOI: 10.1245/s10434-014-3605-x.Peer-Reviewed Original ResearchMeSH KeywordsBreast NeoplasmsConsensusFemaleHumansMaleMastectomy, SegmentalMedical OncologyNeoplasm Recurrence, LocalRadiation OncologySocieties, Medical
2012
Application of ACOSOG Z0011 Criteria Reduces Perioperative Costs
Camp M, Greenup R, Taghian A, Coopey S, Specht M, Gadd M, Hughes K, Smith B. Application of ACOSOG Z0011 Criteria Reduces Perioperative Costs. Annals Of Surgical Oncology 2012, 20: 836-841. PMID: 23010735, DOI: 10.1245/s10434-012-2664-0.Peer-Reviewed Original ResearchMeSH KeywordsAxillaBreast NeoplasmsCombined Modality TherapyCost-Benefit AnalysisFemaleFollow-Up StudiesHumansLymph Node ExcisionLymphatic MetastasisMastectomy, SegmentalNeoplasm Recurrence, LocalNeoplasm StagingPractice Guidelines as TopicPrognosisRetrospective StudiesSentinel Lymph Node BiopsySurvival RateConceptsAxillary lymph node dissectionCompletion axillary lymph node dissectionPerioperative surgical managementOvernight admissionPerioperative costsZ0011 criteriaSurgical managementBreast cancerSentinel lymph node-positive breast cancerLymph node-positive breast cancerNode-positive breast cancerACOSOG Z0011 criteriaACOSOG Z0011 trialOvernight hospital admissionLymph node dissectionRetrospective chart reviewInvasive breast cancerBreast conservation therapyInpatient hospital daysPositive breast cancerExcellent regional controlPositive SLNZ0011 trialEligible patientsNode dissectionCost Comparison of Radiation Treatment Options After Lumpectomy for Breast Cancer
Greenup R, Camp M, Taghian A, Buckley J, Coopey S, Gadd M, Hughes K, Specht M, Smith B. Cost Comparison of Radiation Treatment Options After Lumpectomy for Breast Cancer. Annals Of Surgical Oncology 2012, 19: 3275-3281. PMID: 22851048, DOI: 10.1245/s10434-012-2546-5.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBrachytherapyBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, Intraductal, NoninfiltratingCarcinoma, LobularCombined Modality TherapyCosts and Cost AnalysisFemaleFollow-Up StudiesHealth Care CostsHumansMastectomy, SegmentalMiddle AgedNeoplasm GradingNeoplasm InvasivenessPrognosisRetrospective StudiesConceptsWhole breast radiation therapyBreast cancerRT optionsExternal-beam partial breast irradiationLeukemia Group B 9343MethodsAn institutional review boardResultsMedian patient ageCurrent Procedural Terminology codesMedian tumor sizeInvasive ductal cancerSitu breast cancerPartial breast irradiationProcedural Terminology codesRadiation treatment optionsInstitutional review boardC-RTBackgroundRadiation therapyRT regimensBreast conservationDuctal cancerLobular cancerMixed histologyPatient ageRetrospective reviewTumor histology