Obstructive sleep apnea and the incidence and mortality of gastrointestinal cancers: a systematic review and meta-analysis of 5,120,837 participants
Teo Y, Tan B, Tan N, Yap D, Chai Y, Teo Y, Sia C, Sundar R, Tan E, See A, Toh S. Obstructive sleep apnea and the incidence and mortality of gastrointestinal cancers: a systematic review and meta-analysis of 5,120,837 participants. Journal Of Gastrointestinal Oncology 2022, 0: 0-0. PMID: 36636076, PMCID: PMC9830329, DOI: 10.21037/jgo-22-153.Peer-Reviewed Original ResearchObstructive sleep apneaAssociation of obstructive sleep apneaSleep apneaGastrointestinal cancerCancer incidenceColorectal cancerMeta-analysisPancreatic cancerFollow-upObstructive sleep apnea screeningYears of median follow-upColorectal cancer screening guidelinesLong-term follow-upIncreased risk of colorectal cancerIncreased incidence of colorectal cancerRisk of colorectal cancerIncidence of colorectal cancerMedian follow-upPancreatic cancer incidenceCancer screening guidelinesSleep apnea screeningIncidence of gastrointestinal cancerMortality of gastrointestinal cancersSystematic reviewHigh-risk individualsAssociation of obstructive sleep apnea and nocturnal hypoxemia with all-cancer incidence and mortality: a systematic review and meta-analysis.
Tan B, Teo Y, Tan N, Yap D, Sundar R, Lee C, See A, Toh S. Association of obstructive sleep apnea and nocturnal hypoxemia with all-cancer incidence and mortality: a systematic review and meta-analysis. Journal Of Clinical Sleep Medicine 2022, 18: 1427-1440. PMID: 34755597, PMCID: PMC9059590, DOI: 10.5664/jcsm.9772.Peer-Reviewed Original ResearchConceptsAssociation of obstructive sleep apneaObstructive sleep apneaAll-cancer riskAll-cancer incidenceSevere nocturnal hypoxemiaNocturnal hypoxemiaSleep apneaAll-cancer mortalityModerate obstructive sleep apneaNo/mild OSASevere obstructive sleep apneaObstructive sleep apnea diagnosisObstructive sleep apnea treatmentOxygen desaturation indexMeta-analysisNewcastle-Ottawa ScaleSystematic reviewRandom-effects meta-analysesQuality of evidenceArousal indexDesaturation indexNormoxemic patientsRandomized studyHypoxemiaEvaluated study bias