2022
A Systematic Review and Meta-Analysis of the Effectiveness of Neuroprotectants for Paclitaxel-Induced Peripheral Neuropathy
Leen A, Yap D, Teo C, Tan B, Molassiotis A, Ishiguro H, Fan S, Sundar R, Soon Y, Bandla A. A Systematic Review and Meta-Analysis of the Effectiveness of Neuroprotectants for Paclitaxel-Induced Peripheral Neuropathy. Frontiers In Oncology 2022, 11: 763229. PMID: 35070969, PMCID: PMC8766304, DOI: 10.3389/fonc.2021.763229.Peer-Reviewed Original ResearchPaclitaxel-induced peripheral neuropathyPeripheral neuropathyTreatment arm compared to controlsMeta-analysisPooled resultsNeuroprotective interventionsSide effects of paclitaxelEffects of paclitaxelDisabling side effectsEffect of neuroprotectionNon-pharmacological interventionsNon-pharmacological trialsRelevant controlled trialsNon-pharmacological approachesRandom-effects modelEffective prevention strategiesBiomedical Literature DatabasePrimary outcomePharmacological trialsModerate heterogeneityPrevention strategiesPharmacological interventionsSystematic reviewLiterature databasesIntervention
2018
Cryocompression for enhanced limb hypothermia in preventing paclitaxel-induced peripheral neuropathy.
Sundar R, Bandla A, Tan S, Kumarakulasinghe N, Huang Y, Ang S, Hairom Z, Lim J, Wong A, Chan G, Ngoi N, Ang E, Chan A, Lee S, Thakor N, Wilder-Smith E. Cryocompression for enhanced limb hypothermia in preventing paclitaxel-induced peripheral neuropathy. Journal Of Clinical Oncology 2018, 36: 10095-10095. DOI: 10.1200/jco.2018.36.15_suppl.10095.Peer-Reviewed Original ResearchPaclitaxel-induced peripheral neuropathy
2017
Limb Hypothermia for Preventing Paclitaxel-Induced Peripheral Neuropathy in Breast Cancer Patients: A Pilot Study
Sundar R, Bandla A, Tan S, Liao L, Kumarakulasinghe N, Jeyasekharan A, Ow S, Ho J, Tan D, Lim J, Vijayan J, Therimadasamy A, Hairom Z, Ang E, Ang S, Thakor N, Lee S, Wilder-Smith E. Limb Hypothermia for Preventing Paclitaxel-Induced Peripheral Neuropathy in Breast Cancer Patients: A Pilot Study. Frontiers In Oncology 2017, 6: 274. PMID: 28119855, PMCID: PMC5222823, DOI: 10.3389/fonc.2016.00274.Peer-Reviewed Original ResearchNerve conduction studiesBreast cancer patientsPeripheral neuropathyPaclitaxel infusionLimb hypothermiaPreventing paclitaxel-induced peripheral neuropathyCancer patientsPaclitaxel-induced peripheral neuropathyHistory of diabetes mellitusDose-limiting toxicityCompound muscle action potentialCool limbsMuscle action potentialWeekly paclitaxelSensory velocityDiabetes mellitusGrade 2Contralateral limbAction potentialsPaclitaxelPilot trialPatientsControl limbsHypothermiaTolerance to hypothermia