2022
Association of obstructive sleep apnea and nocturnal hypoxemia with all-cancer incidence and mortality: a systematic review and meta-analysis.
Tan B, Teo Y, Tan N, Yap D, Sundar R, Lee C, See A, Toh S. Association of obstructive sleep apnea and nocturnal hypoxemia with all-cancer incidence and mortality: a systematic review and meta-analysis. Journal Of Clinical Sleep Medicine 2022, 18: 1427-1440. PMID: 34755597, PMCID: PMC9059590, DOI: 10.5664/jcsm.9772.Peer-Reviewed Original ResearchConceptsAssociation of obstructive sleep apneaObstructive sleep apneaAll-cancer riskAll-cancer incidenceSevere nocturnal hypoxemiaNocturnal hypoxemiaSleep apneaAll-cancer mortalityModerate obstructive sleep apneaNo/mild OSASevere obstructive sleep apneaObstructive sleep apnea diagnosisObstructive sleep apnea treatmentOxygen desaturation indexMeta-analysisNewcastle-Ottawa ScaleSystematic reviewRandom-effects meta-analysesQuality of evidenceArousal indexDesaturation indexNormoxemic patientsRandomized studyHypoxemiaEvaluated study bias
2018
A study of 1088 consecutive cases of electrolyte abnormalities in oncology phase I trials
Garces A, Ang J, Ameratunga M, Chénard-Poirier M, Dolling D, Diamantis N, Seeramreddi S, Sundar R, de Bono J, Lopez J, Banerji U. A study of 1088 consecutive cases of electrolyte abnormalities in oncology phase I trials. European Journal Of Cancer 2018, 104: 32-38. PMID: 30316017, PMCID: PMC6259582, DOI: 10.1016/j.ejca.2018.08.019.Peer-Reviewed Original ResearchConceptsPhase I clinical trialElectrolyte abnormalitiesBaseline hypoalbuminaemiaOverall survivalClinical significanceDose-limiting toxicity windowPrognostic factors of OSOncology phase I trialsInferior median OSFactors of OSPhase I patientsPhase I trialRetrospective chart reviewSerum albumin levelAssociated with hypomagnesaemiaRoyal Marsden HospitalCox regression analysisPhase I populationDrug Development UnitMedian OSPrognostic factorsPrognostic significanceI patientsI trialAlbumin levels