The impact of cobalt-60 source age on biologically effective dose in high-dose functional Gamma Knife radiosurgery.
Kann BH, Yu JB, Stahl JM, Bond JE, Loiselle C, Chiang VL, Bindra RS, Gerrard JL, Carlson DJ. The impact of cobalt-60 source age on biologically effective dose in high-dose functional Gamma Knife radiosurgery. Journal Of Neurosurgery 2016, 125: 154-159. PMID: 27903196, DOI: 10.3171/2016.6.gks161497.Peer-Reviewed Original ResearchConceptsTrigeminal neuralgiaGKRS treatmentObsessive-compulsive disorderTN managementEffective doseRefractory obsessive-compulsive disorderGamma Knife radiosurgery proceduresStudy of patientsGamma knife radiosurgeryRates of toxicitySingle-fraction dosesStudy of outcomesNerve ablationSerious sequelaePrescription dosesKnife radiosurgeryPrescription doseClinical studiesConclusion UseGKRSDose prescriptionGy/minRepair halftimeTreatment timeAuthors' departmentA contemporary dose selection algorithm for stereotactic radiosurgery in the treatment of brain metastases - An initial report.
Colaco RJ, Yu JB, Bond JS, Bindra RS, Contessa JN, Knisely JPS, Chiang VL. A contemporary dose selection algorithm for stereotactic radiosurgery in the treatment of brain metastases - An initial report. Journal Of Radiosurgery And SBRT 2016, 4: 43-52. PMID: 29296425, PMCID: PMC5658834.Peer-Reviewed Original ResearchWhole brain radiotherapyDistant intracranial recurrenceLocal recurrenceBrain metastasesRTOG 90Overall local recurrence ratePrevious whole-brain radiotherapyProspective phase 2 trialWhole-brain radiation therapyBrain radiation therapyLocal recurrence rateMonths overall survivalPhase 2 trialRisk regression analysisGuideline dosesBrain radiotherapyPrimary endpointIntracranial recurrenceOverall survivalFine-GrayPrescription dosesRecurrence rateRetrospective outcomesMedical recordsLesion volume