2017
State of the art: the evolving role of RT in combined modality therapy for GBM
Bindra RS, Galanis E, Mehta MP. State of the art: the evolving role of RT in combined modality therapy for GBM. Journal Of Neuro-Oncology 2017, 134: 477-478. PMID: 28913783, PMCID: PMC5866384, DOI: 10.1007/s11060-017-2596-4.Peer-Reviewed Original ResearchGBM radiosensitizers: dead in the water…or just the beginning?
Bindra RS, Chalmers AJ, Evans S, Dewhirst M. GBM radiosensitizers: dead in the water…or just the beginning? Journal Of Neuro-Oncology 2017, 134: 513-521. PMID: 28762004, DOI: 10.1007/s11060-017-2427-7.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrain NeoplasmsCombined Modality TherapyDNA DamageGlioblastomaHumansHypoxiaNeoplasm Recurrence, LocalRadiation-Sensitizing AgentsConceptsPre-clinical evidenceNovel therapeutic approachesGBMs recurDevelopment of radiosensitizersClinical trialsTherapeutic approachesDNA damage response inhibitorsLocal controlPrimary siteDNA repair inhibitorsPotent agentOxidative stressRadiosensitizerRepair inhibitorsRadiosensitizationInhibitorsRadiotherapyClinicHypoxiaTrialsThe role of radiation in treating glioblastoma: here to stay
Corso CD, Bindra RS, Mehta MP. The role of radiation in treating glioblastoma: here to stay. Journal Of Neuro-Oncology 2017, 134: 479-485. PMID: 28271281, DOI: 10.1007/s11060-016-2348-x.Peer-Reviewed Original Research
2016
Postoperative Radiotherapy Patterns of Care and Survival Implications for Medulloblastoma in Young Children
Kann BH, Park HS, Lester-Coll NH, Yeboa DN, Benitez V, Khan AJ, Bindra RS, Marks AM, Roberts KB. Postoperative Radiotherapy Patterns of Care and Survival Implications for Medulloblastoma in Young Children. JAMA Oncology 2016, 2: 1574-1581. PMID: 27491009, DOI: 10.1001/jamaoncol.2016.2547.Peer-Reviewed Original ResearchConceptsPostoperative radiotherapyOverall survivalMultivariable logistic regressionNational Cancer Data BaseLogistic regressionAdjuvant chemotherapy strategyLow facility volumeNational treatment patternsMultivariable Cox regressionLong-term morbidityYear of diagnosisDay of surgeryKaplan-Meier analysisNational database analysisPoor overall survivalLog-rank testYoung childrenAge 3Adjuvant chemotherapyRadiotherapy patternsRadiotherapy utilizationWorse survivalDistant metastasisMultivariable analysisTreatment patternsSuccess and Failures of Combined Modalities in Glioblastoma Multiforme: Old Problems and New Directions
Corso CD, Bindra RS. Success and Failures of Combined Modalities in Glioblastoma Multiforme: Old Problems and New Directions. Seminars In Radiation Oncology 2016, 26: 281-298. PMID: 27619250, DOI: 10.1016/j.semradonc.2016.06.003.Peer-Reviewed Original ResearchMeSH KeywordsBrain NeoplasmsCombined Modality TherapyGlioblastomaHumansImmunotherapyMedical OncologyRadiation-Sensitizing AgentsTreatment OutcomeConceptsCurrent standard treatmentGlioblastoma multiformeStandard treatmentTreatment of GBMDistant brain relapseAggressive intracranial tumorBrain relapseAggressive therapyModality therapySurgical resectionCombined modalityIntracranial tumorsModality approachOncology communityTherapyMultiformeTreatmentUnanswered questionsImmunotherapyResectionRelapseFailureTumors
2013
Radiation sensitivity and sensitization in melanoma
Shahbazian D, Bindra RS, Kluger HM, Glazer PM. Radiation sensitivity and sensitization in melanoma. Pigment Cell & Melanoma Research 2013, 26: 928-930. PMID: 23870422, PMCID: PMC3866027, DOI: 10.1111/pcmr.12147.Peer-Reviewed Original Research
2011
The important role of radiation therapy in early-stage diffuse large B-cell lymphoma: time to review the evidence once again
Bindra RS, Yahalom J. The important role of radiation therapy in early-stage diffuse large B-cell lymphoma: time to review the evidence once again. Expert Review Of Anticancer Therapy 2011, 11: 1367-1378. PMID: 21929311, DOI: 10.1586/era.11.88.Peer-Reviewed Original ResearchConceptsEarly-stage diffuse large B-cell lymphomaDiffuse large B-cell lymphomaLarge B-cell lymphomaB-cell lymphomaLocalized diseaseClinical trialsRadiation therapyAlternative treatment regimenSignificant survival benefitCombined-modality therapyRecent clinical trialsRandomized clinical trialsCombination of chemotherapyIntensive immunochemotherapyConsolidation radiotherapySurvival benefitTreatment regimenRetrospective studyHodgkin's lymphomaMultimodality approachCommon subtypeSuperior efficacyLocal controlAppropriate managementLymphoma