2016
Genetic polymorphisms of PPAR gamma, arsenic methylation capacity and breast cancer risk in Mexican women
Pineda-Belmontes CP, Hernández-Ramírez RU, Hernández-Alcaraz C, Cebrián ME, López-Carrillo L. Genetic polymorphisms of PPAR gamma, arsenic methylation capacity and breast cancer risk in Mexican women. Salud Pública De México 2016, 58: 220-227. PMID: 27557380, DOI: 10.21149/spm.v58i2.7791.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedArsenicArsenicalsBreast NeoplasmsCarrier ProteinsCase-Control StudiesChromatography, High Pressure LiquidEnvironmental ExposureFemaleGenetic Predisposition to DiseaseHumansMass SpectrometryMethylationMiddle AgedPolymerase Chain ReactionPolymorphism, Single NucleotidePPAR gammaRiskRNA-Binding ProteinsYoung AdultConceptsRisk of BCBreast cancerArsenic methylation capacityPolymerase chain reactionMethylation capacityMexican womenBreast cancer riskUrinary arsenic speciesCancer riskPresence of polymorphismsPPAR gammaPolymorphisms of interestUrine samplesGenetic polymorphismsChain reactionWomenHigh-performance liquid chromatographyRiskPolymorphismMethylation ratioSignificant interactionAssociationLiquid chromatography
2013
PPARγ and PPARGC1B polymorphisms modify the association between phthalate metabolites and breast cancer risk
Martínez-Nava GA, Burguete-García AI, López-Carrillo L, Hernández-Ramírez RU, Madrid-Marina V, Cebrián ME. PPARγ and PPARGC1B polymorphisms modify the association between phthalate metabolites and breast cancer risk. Biomarkers 2013, 18: 493-501. PMID: 23866026, DOI: 10.3109/1354750x.2013.816776.Peer-Reviewed Original ResearchMeSH KeywordsBreast NeoplasmsCarrier ProteinsFemaleGenetic Predisposition to DiseaseHumansPhthalic AcidsPolymorphism, Single NucleotidePPAR gammaRNA-Binding ProteinsArsenic Exposure and Calpain-10 Polymorphisms Impair the Function of Pancreatic Beta-Cells in Humans: A Pilot Study of Risk Factors for T2DM
Díaz-Villaseñor A, Cruz L, Cebrián A, Hernández-Ramírez RU, Hiriart M, García-Vargas G, Bassol S, Sordo M, Gandolfi AJ, Klimecki WT, López-Carillo L, Cebrián ME, Ostrosky-Wegman P. Arsenic Exposure and Calpain-10 Polymorphisms Impair the Function of Pancreatic Beta-Cells in Humans: A Pilot Study of Risk Factors for T2DM. PLOS ONE 2013, 8: e51642. PMID: 23349674, PMCID: PMC3551951, DOI: 10.1371/journal.pone.0051642.Peer-Reviewed Original ResearchConceptsBeta-cell functionLower beta-cell functionSNP-43Risk factorsInsulin sensitivitySNP-44IAs exposureSingle nucleotide polymorphismsChronic exposureCAPN-10Type 2 diabetes mellitusOutcomes of T2DMCalpain-10 polymorphismsGenetic risk factorsPancreatic beta cellsAction of insulinCalpain-10 geneDiabetes mellitusInverse associationInsulin secretionT2DMBeta cellsRisk genotypesArsenic exposurePilot study