2022
Identifying the profile of Helicobacter pylori negative gastric cancers: a case only analysis within the Stomach cancer Pooling (StoP) Project
Morais S, Peleteiro B, Araújo N, Malekzadeh R, Ye W, Plymoth A, Tsugane S, Hidaka A, Hamada GS, López-Carrillo L, Zaridze D, Maximovich D, Aragonés N, Castaño-Vinyals G, Pakseresht M, Hernández-Ramírez RU, López-Cervantes M, Leja M, Gasenko E, Pourfarzi F, Zhang ZF, Yu GP, Derakhshan MH, Pelucchi C, Negri E, La Vecchia C, Lunet N. Identifying the profile of Helicobacter pylori negative gastric cancers: a case only analysis within the Stomach cancer Pooling (StoP) Project. Cancer Epidemiology Biomarkers & Prevention 2022, 31: cebp.0402.2021. PMID: 34728467, DOI: 10.1158/1055-9965.epi-21-0402.Peer-Reviewed Original ResearchConceptsStomach cancer Pooling (StoP) ProjectGastric cancerNegative gastric cancerGastric atrophyRisk factorsOdds ratioFamily historyPooling ProjectPositive casesGastric cancer risk factorsInfection statusNon-cardia gastric cancerCancer risk factorsFirst-degree relativesHigh-risk profileAbsence of infectionOccurrence of cancerCurrent smokersPooled prevalenceCagA statusHpNGCSerologic testsLow prevalenceAdvanced stageCancer
2021
Exploring the interactions between Helicobacter pylori (Hp) infection and other risk factors of gastric cancer: A pooled analysis in the Stomach cancer Pooling (StoP) Project
Collatuzzo G, Pelucchi C, Negri E, López‐Carrillo L, Tsugane S, Hidaka A, Hamada G, Hernández‐Ramírez R, López‐Cervantes M, Malekzadeh R, Pourfarzi F, Mu L, Zhang Z, Lunet N, La Vecchia C, Boffetta P. Exploring the interactions between Helicobacter pylori (Hp) infection and other risk factors of gastric cancer: A pooled analysis in the Stomach cancer Pooling (StoP) Project. International Journal Of Cancer 2021, 149: 1228-1238. PMID: 33990950, DOI: 10.1002/ijc.33678.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsStomach cancer Pooling (StoP) ProjectHP infectionRisk factorsGastric cancerSocioeconomic statusCigarette smokingPooled analysisAlcohol drinkingOdds ratioPooling ProjectMultivariate unconditional logistic regressionDietary salt intakeModifiable risk factorsHelicobacter pylori infectionUnconditional logistic regressionGastric cancer preventionConfidence intervalsCase-control studySummary odds ratiosLifestyle modificationHP eradicationSalt intakeTobacco smokingDietary saltHistologic type
2020
Fruits and vegetables intake and gastric cancer risk: A pooled analysis within the Stomach cancer Pooling Project
Ferro A, Costa AR, Morais S, Bertuccio P, Rota M, Pelucchi C, Hu J, Johnson KC, Zhang Z, Palli D, Ferraroni M, Yu G, Bonzi R, Peleteiro B, López‐Carrillo L, Tsugane S, Hamada GS, Hidaka A, Malekzadeh R, Zaridze D, Maximovich D, Vioque J, Navarrete‐Muñoz E, Alguacil J, Castaño‐Vinyals G, Wolk A, Håkansson N, Hernández‐Ramírez R, Pakseresht M, Ward MH, Pourfarzi F, Mu L, López‐Cervantes M, Persiani R, Kurtz RC, Lagiou A, Lagiou P, Boffetta P, Boccia S, Negri E, Camargo MC, Curado MP, La Vecchia C, Lunet N. Fruits and vegetables intake and gastric cancer risk: A pooled analysis within the Stomach cancer Pooling Project. International Journal Of Cancer 2020, 147: 3090-3101. PMID: 32525569, PMCID: PMC8545605, DOI: 10.1002/ijc.33134.Peer-Reviewed Original ResearchConceptsGastric cancerGastric cancer riskNoncitrus fruitProtective effectCancer riskStomach cancer Pooling (StoP) ProjectExposure-response analysisPortions/dayConfidence intervalsExposure-response relationsRandom-effects modelPooled analysisRisk factorsDietary recommendationsLow intakeHigh intakePooling ProjectStudy characteristicsCancerNonlinear associationFractional polynomialsIntakeLifestyle categoriesRiskAssociation
2019
Smoking and Helicobacter pylori infection
Ferro A, Morais S, Pelucchi C, Aragonés N, Kogevinas M, López-Carrillo L, Malekzadeh R, Tsugane S, Hamada GS, Hidaka A, Hernández-Ramírez RU, López-Cervantes M, Zaridze D, Maximovitch D, Pourfarzi F, Zhang ZF, Yu GP, Pakseresht M, Ye W, Plymoth A, Leja M, Gasenko E, Derakhshan MH, Negri E, La Vecchia C, Peleteiro B, Lunet N. Smoking and Helicobacter pylori infection. European Journal Of Cancer Prevention 2019, Publish Ahead of Print: &na;. PMID: 30272597, DOI: 10.1097/cej.0000000000000471.Peer-Reviewed Original ResearchConceptsH. pylori seropositivityHelicobacter pylori infectionPylori infectionPylori seropositivityPrevalence ratiosStomach cancer Pooling (StoP) ProjectDuration of smokingH. pylori infectionCase-control studyConfidence intervalsSummary odds ratiosIndividual participant dataOdds ratioEgger's testGastric cancerStratified analysisMajor covariatesPooling ProjectGreater prevalenceSmokingH. pyloriSignificant associationPublication biasSeropositivityInfectionSex differences in the prevalence of Helicobacter pylori infection: an individual participant data pooled analysis (StoP Project)
Ferro A, Morais S, Pelucchi C, Dierssen-Sotos T, Martín V, López-Carrillo L, Malekzadeh R, Tsugane S, Hamada GS, Hidaka A, Hernández-Ramírez RU, López-Cervantes M, Zaridze D, Maximovitch D, Pourfarzi F, Zhang ZF, Yu GP, Pakseresht M, Ye W, Plymoth A, Leja M, Gasenko E, Derakhshan MH, Negri E, La Vecchia C, Peleteiro B, Lunet N. Sex differences in the prevalence of Helicobacter pylori infection: an individual participant data pooled analysis (StoP Project). European Journal Of Gastroenterology & Hepatology 2019, 31: 593-598. PMID: 30839435, DOI: 10.1097/meg.0000000000001389.Peer-Reviewed Original ResearchConceptsH. pylori infectionHelicobacter pylori infectionPylori infectionPrevalence ratiosOdds ratioGastric atrophyIgG serum antibody titersStomach cancer Pooling (StoP) ProjectPublication biasInfection statusSerum antibody titersConfidence intervalsSummary odds ratiosSerum pepsinogen levelsIndividual participant dataLifetime infectionsMultiplex serologyAntibody titersHistological examinationPooling ProjectPepsinogen levelsOlder controlsInfectionParticipant dataStrong associationEducation and gastric cancer risk—An individual participant data meta‐analysis in the StoP project consortium
Rota M, Alicandro G, Pelucchi C, Bonzi R, Bertuccio P, Hu J, Zhang Z, Johnson KC, Palli D, Ferraroni M, Yu G, Galeone C, López‐Carrillo L, Muscat J, Lunet N, Ferro A, Ye W, Plymoth A, Malekzadeh R, Zaridze D, Maximovitch D, Kogevinas M, de Larrea N, Vioque J, Navarrete‐Muñoz E, Tsugane S, Hamada GS, Hidaka A, Pakseresht M, Wolk A, Håkansson N, Hernández‐Ramírez R, López‐Cervantes M, Ward M, Pourfarzi F, Mu L, Kurtz RC, Lagiou A, Lagiou P, Boffetta P, Boccia S, Negri E, La Vecchia C. Education and gastric cancer risk—An individual participant data meta‐analysis in the StoP project consortium. International Journal Of Cancer 2019, 146: 671-681. PMID: 30919464, DOI: 10.1002/ijc.32298.Peer-Reviewed Original ResearchConceptsGastric cancer riskIndividual participant dataOdds ratioCancer riskSocioeconomic positionHighest household income categoryStomach cancer Pooling (StoP) ProjectStudy-specific odds ratiosH. pylori-negative subjectsGC riskParticipant dataPylori-negative subjectsStrong risk factorRandom-effects meta-analytic modelConfidence intervalsPooled odds ratioStrong inverse associationLow socioeconomic positionPublic health interventionsHousehold income categoryNegative subjectsInverse associationRisk factorsPooling ProjectPremature mortalityAssociation of immunosuppression and HIV viraemia with non-Hodgkin lymphoma risk overall and by subtype in people living with HIV in Canada and the USA: a multicentre cohort study
Hernández-Ramírez RU, Qin L, Lin H, Leyden W, Neugebauer RS, Althoff KN, Achenbach CJ, Hessol NA, D'Souza G, Gebo KA, Gill MJ, Grover S, Horberg MA, Li J, Mathews WC, Mayor AM, Park LS, Rabkin CS, Salters K, Justice AC, Moore RD, Engels EA, Silverberg MJ, Dubrow R, AIDS N, Betts A, Brooks J, Freeman A, Van Rompaey S, Burchell A, Yip B, You B, Hogan B, Grasso C, Hogg R, Benson C, Drozd D, Sterling T, Haas D, Humes E, Crane H, Willig J, Eron J, Martin J, Saag M, Jing J, Zhang J, Lindsay J, Hunter-Mellado R, Deeks S, Zhu J, Montaner J, McReynolds J, Gabler K, Buchacz K, Rodriguez B, Thorne J, Margolick J, Anastos K, Jacobson L, Klein M, Kroch A, Morton L, Turner M, Fiellin D, Gange S, Mugavero M, Harrigan P, Rebeiro P, Bosch R, Kirk G, Mayer K, McKaig R, Coburn S, Napravnik S, Kitahata M, Lober W, Lee J. Association of immunosuppression and HIV viraemia with non-Hodgkin lymphoma risk overall and by subtype in people living with HIV in Canada and the USA: a multicentre cohort study. The Lancet HIV 2019, 6: e240-e249. PMID: 30826282, PMCID: PMC6531288, DOI: 10.1016/s2352-3018(18)30360-6.Peer-Reviewed Original ResearchConceptsNon-Hodgkin lymphomaRecent CD4 countCD4 countHIV viraemiaKey independent predictorsViral loadIndependent predictorsNorth American AIDS Cohort CollaborationCNS non-Hodgkin's lymphomaOverall non-Hodgkin lymphomaDiffuse large B-cell lymphomaLarge B-cell lymphomaAssociation of immunosuppressionMulticentre cohort studyNon-Hodgkin lymphoma (NHL) riskAverage viral loadUS Health ResourcesB-cell lymphomaOverall immune functionB cell activationLong-term careCohort CollaborationRecent immunosuppressionAntiretroviral therapyCohort studyCitrus fruit intake and gastric cancer: The stomach cancer pooling (StoP) project consortium
Bertuccio P, Alicandro G, Rota M, Pelucchi C, Bonzi R, Galeone C, Bravi F, Johnson KC, Hu J, Palli D, Ferraroni M, López‐Carrillo L, Lunet N, Ferro A, Malekzadeh R, Zaridze D, Maximovitch D, Vioque J, Navarrete‐Munoz E, Pakseresht M, Hernández‐Ramírez R, López‐Cervantes M, Ward M, Pourfarzi F, Tsugane S, Hidaka A, Zhang Z, Kurtz RC, Lagiou P, Lagiou A, Boffetta P, Boccia S, Negri E, La Vecchia C. Citrus fruit intake and gastric cancer: The stomach cancer pooling (StoP) project consortium. International Journal Of Cancer 2019, 144: 2936-2944. PMID: 30521095, DOI: 10.1002/ijc.32046.Peer-Reviewed Original ResearchConceptsCitrus fruit intakeStomach cancer pooling (StoP) project consortiumGastric cancerFruit intakeOdds ratioPrevious cohort studiesServings/weekConfidence intervalsCase-control studyCitrus fruit consumptionGastric cancer riskCohort studyInverse associationRisk factorsProtective effectCitrus fruitsCancer riskHighest thirdNull associationProtective roleLinear mixed effects modelsCancerFruit consumptionFavorable effectMixed effects models
2017
Cancer risk in HIV-infected people in the USA from 1996 to 2012: a population-based, registry-linkage study
Hernández-Ramírez RU, Shiels MS, Dubrow R, Engels EA. Cancer risk in HIV-infected people in the USA from 1996 to 2012: a population-based, registry-linkage study. The Lancet HIV 2017, 4: e495-e504. PMID: 28803888, PMCID: PMC5669995, DOI: 10.1016/s2352-3018(17)30125-x.Peer-Reviewed Original ResearchConceptsStandardised incidence ratiosRegistry linkage studyVirus-related cancersCancer riskGeneral populationCancer RegistryModern antiretroviral therapy (ART) eraAntiretroviral therapy eraPopulation-based HIVUSA general populationCohort of HIVNon-Hodgkin lymphomaDiagnosis of cancerNational Cancer InstituteSIR differenceTherapy eraCancer overallIncident cancerMultivariable adjustmentART exposureIncidence ratiosAIDS onsetCommon cancerLung cancerKaposi's sarcoma
2016
Dietary micronutrient intake and its relationship with arsenic metabolism in Mexican women
López-Carrillo L, Gamboa-Loira B, Becerra W, Hernández-Alcaraz C, Hernández-Ramírez RU, Gandolfi AJ, Franco-Marina F, Cebrián ME. Dietary micronutrient intake and its relationship with arsenic metabolism in Mexican women. Environmental Research 2016, 151: 445-450. PMID: 27565879, PMCID: PMC5457700, DOI: 10.1016/j.envres.2016.08.015.Peer-Reviewed Original ResearchConceptsMetabolism of iAsDietary micronutrient intakeFood frequency questionnaireMagnitude of exposureFrequency questionnaireDietary interventionDiet contributesDietary factorsDietary intakeMicronutrient intakeUrinary metabolitesVitamin B12Mexican womenInterindividual variationIntakeFurther studiesHigh-performance liquid chromatographyConsequent riskWomenPerformance liquid chromatographyMetabolismIAArsenic metabolismInorganic arsenicExposureGenetic polymorphisms of PPAR gamma, arsenic methylation capacity and breast cancer risk in Mexican women
Pineda-Belmontes CP, Hernández-Ramírez RU, Hernández-Alcaraz C, Cebrián ME, López-Carrillo L. Genetic polymorphisms of PPAR gamma, arsenic methylation capacity and breast cancer risk in Mexican women. Salud Pública De México 2016, 58: 220-227. PMID: 27557380, DOI: 10.21149/spm.v58i2.7791.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedArsenicArsenicalsBreast NeoplasmsCarrier ProteinsCase-Control StudiesChromatography, High Pressure LiquidEnvironmental ExposureFemaleGenetic Predisposition to DiseaseHumansMass SpectrometryMethylationMiddle AgedPolymerase Chain ReactionPolymorphism, Single NucleotidePPAR gammaRiskRNA-Binding ProteinsYoung AdultConceptsRisk of BCBreast cancerArsenic methylation capacityPolymerase chain reactionMethylation capacityMexican womenBreast cancer riskUrinary arsenic speciesCancer riskPresence of polymorphismsPPAR gammaPolymorphisms of interestUrine samplesGenetic polymorphismsChain reactionWomenHigh-performance liquid chromatographyRiskPolymorphismMethylation ratioSignificant interactionAssociationLiquid chromatography
2014
Utilización correcta de las técnicas de detección de cáncer de mama en mujeres mexicanas
López-Carrillo L, Torres-Sánchez L, Blanco-Muñoz J, Hernández-Ramírez RU, Knaul FM. Utilización correcta de las técnicas de detección de cáncer de mama en mujeres mexicanas. Salud Pública De México 2014, 56: 538-546. PMID: 25604299, DOI: 10.21149/spm.v56i5.7711.Peer-Reviewed Original ResearchDietary Patterns and Gastric Cancer Risk in Mexico
Denova-Gutiérrez E, Hernández-Ramírez RU, López-Carrillo L. Dietary Patterns and Gastric Cancer Risk in Mexico. Nutrition And Cancer 2014, 66: 369-376. PMID: 24628363, DOI: 10.1080/01635581.2014.884237.Peer-Reviewed Original ResearchConceptsDietary patternsGastric cancerGC riskPopulation-based case-control studyLower GC riskMajor dietary patternsHealthy dietary patternCase-control studyMultiple epidemiological studiesGastric cancer riskConsumption of vegetablesExtreme quintilesHighest quintileLowest quintileCancer riskEpidemiological studiesFood groupsSignificant associationGC casesP-trendIndividual foodsQuintilePattern 1RiskWhite meat
2013
Arsenic Exposure and Calpain-10 Polymorphisms Impair the Function of Pancreatic Beta-Cells in Humans: A Pilot Study of Risk Factors for T2DM
Díaz-Villaseñor A, Cruz L, Cebrián A, Hernández-Ramírez RU, Hiriart M, García-Vargas G, Bassol S, Sordo M, Gandolfi AJ, Klimecki WT, López-Carillo L, Cebrián ME, Ostrosky-Wegman P. Arsenic Exposure and Calpain-10 Polymorphisms Impair the Function of Pancreatic Beta-Cells in Humans: A Pilot Study of Risk Factors for T2DM. PLOS ONE 2013, 8: e51642. PMID: 23349674, PMCID: PMC3551951, DOI: 10.1371/journal.pone.0051642.Peer-Reviewed Original ResearchConceptsBeta-cell functionLower beta-cell functionSNP-43Risk factorsInsulin sensitivitySNP-44IAs exposureSingle nucleotide polymorphismsChronic exposureCAPN-10Type 2 diabetes mellitusOutcomes of T2DMCalpain-10 polymorphismsGenetic risk factorsPancreatic beta cellsAction of insulinCalpain-10 geneDiabetes mellitusInverse associationInsulin secretionT2DMBeta cellsRisk genotypesArsenic exposurePilot study
2012
Capsaicin consumption, Helicobacter pylori CagA status and IL1B-31C>T genotypes: A host and environment interaction in gastric cancer
López-Carrillo L, Camargo MC, Schneider BG, Sicinschi LA, Hernández-Ramírez RU, Correa P, Cebrian ME. Capsaicin consumption, Helicobacter pylori CagA status and IL1B-31C>T genotypes: A host and environment interaction in gastric cancer. Food And Chemical Toxicology 2012, 50: 2118-2122. PMID: 22414649, PMCID: PMC3636974, DOI: 10.1016/j.fct.2012.02.043.Peer-Reviewed Original ResearchConceptsGastric cancerCagA statusHelicobacter pylori CagA statusGC riskH. pylori CagA statusConsumption of capsaicinFood frequency questionnaireUnconditional logistic regressionHigh-risk individualsVirulent H. pyloriFrequency questionnaireClinical controlGC patientsRisk individualsT genotypeGene-environment interactionsMortality ratePotential interactionsIL1B -31CH. pyloriSusceptible individualsMortality trendsCapsaicin consumptionLogistic regressionTaqMan assays
2011
Validity and reproducibility of a food frequency questionnaire to estimate folate intake in a Mexican population.
Galván-Portillo M, Torres-Sánchez L, Hernández-Ramírez RU, Anaya-Loyola MA. Validity and reproducibility of a food frequency questionnaire to estimate folate intake in a Mexican population. Salud Pública De México 2011, 53: 237-46. PMID: 21829889, DOI: 10.1590/s0036-36342011000300008.Peer-Reviewed Original ResearchPersonal care product use and urinary levels of phthalate metabolites in Mexican women
Romero-Franco M, Hernández-Ramírez RU, Calafat AM, Cebrián ME, Needham LL, Teitelbaum S, Wolff MS, López-Carrillo L. Personal care product use and urinary levels of phthalate metabolites in Mexican women. Environment International 2011, 37: 867-871. PMID: 21429583, DOI: 10.1016/j.envint.2011.02.014.Peer-Reviewed Original ResearchConceptsMono-3-carboxypropyl phthalateMono-n-butyl phthalateMono-2-ethylhexyl phthalatePhthalate metabolitesUrinary concentrationsMonoethyl phthalateUrinary levelsPopulation-based case-control studyOngoing population-based case-control studyPersonal care product useMono-isobutyl phthalateHigh-performance liquid chromatography isotope-dilution tandem mass spectrometryCase-control studyDetectable urinary concentrationsCarboxypentyl phthalateHydroxyhexyl phthalateOxohexyl phthalateBreast cancerLiquid chromatography-isotope dilution tandem mass spectrometryMonobenzyl phthalateReproductive historySociodemographic characteristicsGenetic susceptibilityPotential health impactsMexican women
2009
Dietary intake of polyphenols, nitrate and nitrite and gastric cancer risk in Mexico City
Hernández‐Ramírez R, Galván‐Portillo M, Ward MH, Agudo A, González CA, Oñate‐Ocaña L, Herrera‐Goepfert R, Palma‐Coca O, López‐Carrillo L. Dietary intake of polyphenols, nitrate and nitrite and gastric cancer risk in Mexico City. International Journal Of Cancer 2009, 125: 1424-1430. PMID: 19449378, PMCID: PMC2787087, DOI: 10.1002/ijc.24454.Peer-Reviewed Original ResearchConceptsHigh intakeGastric cancerGC riskN-nitroso compoundsPopulation-based case-control studyFood frequency questionnaireIntake of polyphenolsCase-control studyGastric cancer riskPotent animal carcinogensFrequency questionnaireDietary intakeNitrite intakeLow intakeProtective effectCancer riskDietary polyphenolsEndogenous nitrosationTotal nitriteDiffuse typeCombined consumptionPotential human carcinogensGC casesNOC precursorsIntake