2016
Phthalate exposure, flavonoid consumption and breast cancer risk among Mexican women
Mérida-Ortega Á, Hernández-Alcaraz C, Hernández-Ramírez RU, García-Martínez A, Trejo-Valdivia B, Salinas-Rodríguez A, Svensson K, Cebrián ME, Franco-Marina F, López-Carrillo L. Phthalate exposure, flavonoid consumption and breast cancer risk among Mexican women. Environment International 2016, 96: 167-172. PMID: 27690147, DOI: 10.1016/j.envint.2016.08.023.Peer-Reviewed Original ResearchConceptsBreast cancer riskPhthalate exposureCancer riskSemiquantitative food frequency questionnaireFood frequency questionnaireRisk of BCFrequency questionnaireFlavonoid consumptionHealthy controlsHigh intakePlace of residenceFood groupsTypes of flavonoidsMexican womenUrine samplesRiskMultiplicative interactionFurther investigationWomenNegative associationExposureButyl benzylFlavonoidsTandem mass spectrometryIntakeGenetic polymorphisms of PPAR gamma, arsenic methylation capacity and breast cancer risk in Mexican women
Pineda-Belmontes CP, Hernández-Ramírez RU, Hernández-Alcaraz C, Cebrián ME, López-Carrillo L. Genetic polymorphisms of PPAR gamma, arsenic methylation capacity and breast cancer risk in Mexican women. Salud Pública De México 2016, 58: 220-227. PMID: 27557380, DOI: 10.21149/spm.v58i2.7791.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedArsenicArsenicalsBreast NeoplasmsCarrier ProteinsCase-Control StudiesChromatography, High Pressure LiquidEnvironmental ExposureFemaleGenetic Predisposition to DiseaseHumansMass SpectrometryMethylationMiddle AgedPolymerase Chain ReactionPolymorphism, Single NucleotidePPAR gammaRiskRNA-Binding ProteinsYoung AdultConceptsRisk of BCBreast cancerArsenic methylation capacityPolymerase chain reactionMethylation capacityMexican womenBreast cancer riskUrinary arsenic speciesCancer riskPresence of polymorphismsPPAR gammaPolymorphisms of interestUrine samplesGenetic polymorphismsChain reactionWomenHigh-performance liquid chromatographyRiskPolymorphismMethylation ratioSignificant interactionAssociationLiquid chromatography
2013
Arsenic Exposure and Calpain-10 Polymorphisms Impair the Function of Pancreatic Beta-Cells in Humans: A Pilot Study of Risk Factors for T2DM
Díaz-Villaseñor A, Cruz L, Cebrián A, Hernández-Ramírez RU, Hiriart M, García-Vargas G, Bassol S, Sordo M, Gandolfi AJ, Klimecki WT, López-Carillo L, Cebrián ME, Ostrosky-Wegman P. Arsenic Exposure and Calpain-10 Polymorphisms Impair the Function of Pancreatic Beta-Cells in Humans: A Pilot Study of Risk Factors for T2DM. PLOS ONE 2013, 8: e51642. PMID: 23349674, PMCID: PMC3551951, DOI: 10.1371/journal.pone.0051642.Peer-Reviewed Original ResearchConceptsBeta-cell functionLower beta-cell functionSNP-43Risk factorsInsulin sensitivitySNP-44IAs exposureSingle nucleotide polymorphismsChronic exposureCAPN-10Type 2 diabetes mellitusOutcomes of T2DMCalpain-10 polymorphismsGenetic risk factorsPancreatic beta cellsAction of insulinCalpain-10 geneDiabetes mellitusInverse associationInsulin secretionT2DMBeta cellsRisk genotypesArsenic exposurePilot study
2011
Personal care product use and urinary levels of phthalate metabolites in Mexican women
Romero-Franco M, Hernández-Ramírez RU, Calafat AM, Cebrián ME, Needham LL, Teitelbaum S, Wolff MS, López-Carrillo L. Personal care product use and urinary levels of phthalate metabolites in Mexican women. Environment International 2011, 37: 867-871. PMID: 21429583, DOI: 10.1016/j.envint.2011.02.014.Peer-Reviewed Original ResearchConceptsMono-3-carboxypropyl phthalateMono-n-butyl phthalateMono-2-ethylhexyl phthalatePhthalate metabolitesUrinary concentrationsMonoethyl phthalateUrinary levelsPopulation-based case-control studyOngoing population-based case-control studyPersonal care product useMono-isobutyl phthalateHigh-performance liquid chromatography isotope-dilution tandem mass spectrometryCase-control studyDetectable urinary concentrationsCarboxypentyl phthalateHydroxyhexyl phthalateOxohexyl phthalateBreast cancerLiquid chromatography-isotope dilution tandem mass spectrometryMonobenzyl phthalateReproductive historySociodemographic characteristicsGenetic susceptibilityPotential health impactsMexican women
2009
Exposure to Phthalates and Breast Cancer Risk in Northern Mexico
López-Carrillo L, Hernández-Ramírez RU, Calafat AM, Torres-Sánchez L, Galván-Portillo M, Needham LL, Ruiz-Ramos R, Cebrián ME. Exposure to Phthalates and Breast Cancer Risk in Northern Mexico. Environmental Health Perspectives 2009, 118: 539-544. PMID: 20368132, PMCID: PMC2854732, DOI: 10.1289/ehp.0901091.Peer-Reviewed Original ResearchMeSH KeywordsBreast NeoplasmsCase-Control StudiesEnvironmental ExposureFemaleHumansMexicoMiddle AgedPhthalic AcidsRisk FactorsConceptsBreast cancerMonoethyl phthalatePhthalate metabolitesUrinary concentrationsRisk of BCMono-n-butyl phthalateBreast cancer riskGeometric mean concentrationsPremenopausal womenRisk factorsParent phthalatesCancer riskMonobenzyl phthalateBC casesSignificant negative associationEndocrine systemMexican womenUrine samplesUbiquitous environmental pollutantWomenHigh-performance liquid chromatographyAssociationNegative associationExposureMCPP