2018
Superior Pituitary Border Analysis in Immunotherapy-Induced Hypophysitis
Pucar D, Boustani AM, Bronen RA, Saperstein L. Superior Pituitary Border Analysis in Immunotherapy-Induced Hypophysitis. Clinical Nuclear Medicine 2018, 43: 284-286. PMID: 29401149, DOI: 10.1097/rlu.0000000000001981.Peer-Reviewed Educational MaterialsConceptsSinus diseasePituitary swellingSevere headacheVisual disturbancesLaboratory findingsMetastatic melanomaPituitary abnormalitiesRetrospective analysisContrast CTNoncontrast CTPituitary hormonesHypophysitisHeadacheDiseaseDiagnosisCTLow levelsNivolumabHypermetabolismImmunotherapyPETMelanomaAbnormalitiesFindingsHormone
2010
Whole-exome sequencing identifies recessive WDR62 mutations in severe brain malformations
Bilgüvar K, Öztürk A, Louvi A, Kwan KY, Choi M, Tatlı B, Yalnızoğlu D, Tüysüz B, Çağlayan A, Gökben S, Kaymakçalan H, Barak T, Bakırcıoğlu M, Yasuno K, Ho W, Sanders S, Zhu Y, Yılmaz S, Dinçer A, Johnson MH, Bronen RA, Koçer N, Per H, Mane S, Pamir MN, Yalçınkaya C, Kumandaş S, Topçu M, Özmen M, Šestan N, Lifton RP, State MW, Günel M. Whole-exome sequencing identifies recessive WDR62 mutations in severe brain malformations. Nature 2010, 467: 207-210. PMID: 20729831, PMCID: PMC3129007, DOI: 10.1038/nature09327.Peer-Reviewed Original ResearchConceptsAbnormal cortical developmentWD repeat domain 62 (WDR62) geneSevere brain malformationsWhole-exome sequencingBrain abnormalitiesBrain malformationsCortical developmentMolecular pathogenesisCerebellar hypoplasiaWDR62 mutationsEmbryonic neurogenesisDiagnostic classificationMicrocephaly genesSmall family sizeGenetic heterogeneityWide spectrumRecessive mutationsPachygyriaPathogenesisHypoplasiaNeocortexNeurogenesisAbnormalitiesMalformationsMutations
1997
A systematic approach for interpreting MR images of the seizure patient.
Bronen RA, Fulbright RK, Kim JH, Spencer SS, Spencer DD. A systematic approach for interpreting MR images of the seizure patient. American Journal Of Roentgenology 1997, 169: 241-7. PMID: 9207533, DOI: 10.2214/ajr.169.1.9207533.Peer-Reviewed Original ResearchConceptsSubtle cortical abnormalitiesFalse-negative diagnosesHippocampal sclerosisAbnormal findingsEpileptogenic lesionsCortical thickeningSeizure patientsCortical abnormalitiesLateral ventriclePeriventricular regionEpilepsy patientsMR findingsHigh indexMorphologic abnormalitiesPeriventricular heterotopiaDual abnormalitiesGray matterDevelopmental anomaliesAbnormalitiesMR scansCortical processesMass effectHead rotationPatientsHippocampus
1996
Refractory epilepsy: comparison of MR imaging, CT, and histopathologic findings in 117 patients.
Bronen RA, Fulbright RK, Spencer DD, Spencer SS, Kim JH, Lange RC, Sutilla C. Refractory epilepsy: comparison of MR imaging, CT, and histopathologic findings in 117 patients. Radiology 1996, 201: 97-105. PMID: 8816528, DOI: 10.1148/radiology.201.1.8816528.Peer-Reviewed Original Research