2006
Volumetry of amygdala and hippocampus and memory performance in Alzheimer's disease
Basso M, Yang J, Warren L, MacAvoy MG, Varma P, Bronen RA, van Dyck CH. Volumetry of amygdala and hippocampus and memory performance in Alzheimer's disease. Psychiatry Research 2006, 146: 251-261. PMID: 16524704, DOI: 10.1016/j.pscychresns.2006.01.007.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingAD patientsAmygdaloid volumesAlzheimer's diseaseHealthy controlsHippocampal volumeAlzheimer's Disease Assessment Scale-CognitionMedial temporal lobe atrophyTemporal lobe atrophyOlder healthy subjectsADAS-Cog subscaleHealthy control samplesLobe atrophyAD groupHealthy subjectsAnalysis of covarianceMRI studiesProdromal stagePatientsResonance imagingMildest symptomsNeuropsychological assessmentNeuropsychological performanceHippocampusDisease
2005
Apolipoprotein E epsilon4 is associated with atrophy of the amygdala in Alzheimer's disease
Basso M, Gelernter J, Yang J, MacAvoy MG, Varma P, Bronen RA, van Dyck CH. Apolipoprotein E epsilon4 is associated with atrophy of the amygdala in Alzheimer's disease. Neurobiology Of Aging 2005, 27: 1416-1424. PMID: 16182410, DOI: 10.1016/j.neurobiolaging.2005.08.002.Peer-Reviewed Original ResearchConceptsAlzheimer's diseaseAD patientsAPOE epsilon4AD groupImportant genetic risk factorApolipoprotein E epsilon4Regional brain atrophyAPOE epsilon4 alleleElderly control subjectsNormal elderly control subjectsGenetic risk factorsAmygdaloid volumesBrain atrophyControl subjectsEpsilon4 carriersRisk factorsEpsilon4 alleleHippocampal volumeEpsilon4 doseAnalysis of covarianceDisease severityPatientsEpsilon4AmygdalaAtrophy
2004
MR imaging of the temporal stem: anatomic dissection tractography of the uncinate fasciculus, inferior occipitofrontal fasciculus, and Meyer's loop of the optic radiation.
Kier EL, Staib LH, Davis LM, Bronen RA. MR imaging of the temporal stem: anatomic dissection tractography of the uncinate fasciculus, inferior occipitofrontal fasciculus, and Meyer's loop of the optic radiation. American Journal Of Neuroradiology 2004, 25: 677-91. PMID: 15140705, PMCID: PMC7974480.Peer-Reviewed Original ResearchConceptsInferior occipitofrontal fasciculusTemporal stemMeyer's loopOccipitofrontal fasciculusUncinate fasciculusMR anatomyOptic radiationExtreme capsuleTemporal lobeLateral geniculate bodyAnterior temporal lobeCross-sectional MR imagesPostoperative complicationsTumor spreadExternal capsuleGeniculate bodyAnterior commissureAnatomic foundationAnatomic featuresBrain disordersAlzheimer's diseaseMR imagingDiffusion tractographyFasciculusTract
1996
Comparison of technetium-99m-HMPAO and technetium-99m-ECD cerebral SPECT images in Alzheimer's disease.
van Dyck CH, Lin CH, Smith EO, Wisniewski G, Cellar J, Robinson R, Narayan M, Bennett A, Delaney RC, Bronen RA, Hoffer PB. Comparison of technetium-99m-HMPAO and technetium-99m-ECD cerebral SPECT images in Alzheimer's disease. Journal Of Nuclear Medicine 1996, 37: 1749-55. PMID: 8917168.Peer-Reviewed Original ResearchConceptsControl subjectsAD patientsAlzheimer's diseaseAge-matched control subjectsBrain structuresBrain perfusion agentHigh diagnostic accuracyTechnetium-99mCysteinate dimerHealthy subjectsPatientsDiagnostic groupsPerfusion agentDiagnostic accuracyDiseaseSignificant differencesDiagnostic toolSPECT imagesSubjectsPurported advantagesCharacteristic analysisSignificant interactionCerebral imagesAnalysis of varianceCount density
1991
MRI of the temporal lobe: Normal variations, with special reference toward epilepsy
Bronen R, Cheung G. MRI of the temporal lobe: Normal variations, with special reference toward epilepsy. Magnetic Resonance Imaging 1991, 9: 501-507. PMID: 1779721, DOI: 10.1016/0730-725x(91)90036-l.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingTemporal hornTemporal lobeCollateral sulcusCoronal magnetic resonance imagingTemporal horn dilatationMild asymmetryRight temporal lobeTemporal lobe structuresHippocampal sclerosisChoroidal fissureNormal variationMild enlargementFrequent findingHippocampal headNormal volunteersWhite matterAlzheimer's diseaseResonance imagingLobe structuresOccipitotemporal sulcusAdjacent vesselsHead rotationSclerosisSulcus