2022
The changing landscape in epilepsy imaging: Unmasking subtle and unique entities
Adin ME, Department of Radiology and Biomedical Imaging Y, Durand D, Zucconi W, Huttner A, Spencer D, Bronen R, Department of Radiology Abbott Northwestern Hospital M, Department of Pathology Y, Department of Neurosurgery Y. The changing landscape in epilepsy imaging: Unmasking subtle and unique entities. Diagnostic And Interventional Radiology 2022, 28: 503-515. PMID: 35997478, PMCID: PMC9682800, DOI: 10.5152/dir.2022.21339.Peer-Reviewed Original ResearchConceptsHippocampal sclerosisCortical developmentLocalization-related epilepsyTemporal lobe encephaloceleFocal cortical dysplasiaFocal cortical dysplasia IIbField of epilepsyEpileptogenic abnormalitiesAutoimmune encephalitisRasmussen's encephalitisCommon etiologyCortical dysplasiaEpilepsy surgeryEpileptogenic substrateTuberous sclerosisEpilepsy imagingHippocampal malformationsMTOR pathwayEncephalitisSclerosisMR imagingMalformationsUnique entitySurgeryEpilepsy
2004
Long-term outcome after epilepsy surgery for focal cortical dysplasia.
Cohen-Gadol AA, Ozduman K, Bronen RA, Kim JH, Spencer DD. Long-term outcome after epilepsy surgery for focal cortical dysplasia. Journal Of Neurosurgery 2004, 101: 55-65. PMID: 15255252, DOI: 10.3171/jns.2004.101.1.0055.Peer-Reviewed Original ResearchConceptsFocal cortical dysplasiaImproved seizure outcomeLong-term outcomesCortical dysplasiaClear marginsEpileptogenic zoneSeizure outcomeMean ageMean durationRisk factorsCortical developmentIntracranial monitoringObvious risk factorsRare disabling seizuresTransient sensorimotor deficitsMultiple subpial transectionsSubgroup of patientsExtent of resectionVisual field defectsInclusion of patientsNormal functional anatomyReports of outcomesMagnetic resonance imagingFunctional MR imagingPartial lesionectomy
1998
Surgical outcome in occipital lobe epilepsy: Implications for pathophysiology
Aykut‐Bingol C, Bronen R, Kim J, Spencer D, Spencer S. Surgical outcome in occipital lobe epilepsy: Implications for pathophysiology. Annals Of Neurology 1998, 44: 60-69. PMID: 9667593, DOI: 10.1002/ana.410440112.Peer-Reviewed Original ResearchConceptsOccipital lobe epilepsyClinical seizure characteristicsFocal cortical dysplasiaLobe epilepsyLobe locationPathological substrateSeizure characteristicsSurgical outcomesCortical dysplasiaSurgical approachSurgical proceduresRefractory occipital lobe epilepsyDevelopmental abnormalitiesOccipital lobe seizuresChronic inflammatory changesSturge-Weber syndromeMain pathological substrateOccipital lobe tumorElectroclinical variablesElectroclinical featuresMost patientsSeizure controlChronic epilepsyInflammatory changesLobe tumors
1997
Focal cortical dysplasia of Taylor, balloon cell subtype: MR differentiation from low-grade tumors.
Bronen RA, Vives KP, Kim JH, Fulbright RK, Spencer SS, Spencer DD. Focal cortical dysplasia of Taylor, balloon cell subtype: MR differentiation from low-grade tumors. American Journal Of Neuroradiology 1997, 18: 1141-51. PMID: 9194442, PMCID: PMC8337292.Peer-Reviewed Original ResearchConceptsFocal cortical dysplasiaLow-grade tumorsCortical dysplasiaMR findingsLobe locationLow-grade glial neoplasmTemporal lobe locationSubcortical white matterFrontal lobe locationSurgical resectionCortical thickeningClinical variablesIntractable epilepsyGlial neoplasmsHyperintense signalLateral ventricleMR featuresWhite matterNeoplastic tissueCell subtypesDysplasiaPatientsMR variablesNeoplasmsSurgical planning