1997
Positron Emission Tomography Measurement of Cerebral Metabolic Correlates of Tryptophan Depletion—Induced Depressive Relapse
Bremner JD, Innis RB, Salomon RM, Staib LH, Ng CK, Miller HL, Bronen RA, Krystal JH, Duncan J, Rich D, Price LH, Malison R, Dey H, Soufer R, Charney DS. Positron Emission Tomography Measurement of Cerebral Metabolic Correlates of Tryptophan Depletion—Induced Depressive Relapse. JAMA Psychiatry 1997, 54: 364-374. PMID: 9107153, DOI: 10.1001/archpsyc.1997.01830160092012.Peer-Reviewed Original ResearchConceptsCerebral metabolic correlatesDepressive relapseBrain metabolismMajor depressionMiddle frontal gyrusOrbitofrontal cortexTryptophan depletionMetabolic correlatesPositron emission tomography scanningFrontal gyrusRelapse-prone patientsPathogenesis of depressionPositron emission tomography (PET) measurementsSerotonin reuptake inhibitorsSymptoms of patientsPositron emission tomographySingle photon emissionSpecific brain regionsDorsolateral prefrontal cortexReuptake inhibitorsPlasma tryptophanLimbic regionsCaudate nucleusDepressive symptomsPatients
1996
The Functional Organization of Brain for Reading and Reading Disability (Dyslexia
Shaywitz B, Shaywitz S, Pugh K, Skudlarski P, Fulbright R, Constable R, Fletcher J, Liberman A, Shankweiler D, Katz L, Bronen R, Marchione K, Lacadie C, Gore J. The Functional Organization of Brain for Reading and Reading Disability (Dyslexia. The Neuroscientist 1996, 2: 245-255. DOI: 10.1177/107385849600200413.Peer-Reviewed Original ResearchFunctional magnetic resonance imagingPhonological processingLeft inferior frontal gyrusCore cognitive componentLexical-semantic processingInferior frontal gyrusFunctional organizationPhonological tasksCognitive componentsIFG regionsReading DisabilitiesFrontal gyrusComponent processesLanguage functionBilateral activationLinguistic systemWomen's performanceDyslexiaSex differencesReadingConsistent findingCerebral localizationProcessingTaskLanguage
1995
Sex differences in the functional organization of the brain for language
Shaywitz B, Shaywltz S, Pugh K, Constable R, Skudlarski P, Fulbright R, Bronen R, Fletcher J, Shankweiler D, Katz L, Gore J. Sex differences in the functional organization of the brain for language. Nature 1995, 373: 607-609. PMID: 7854416, DOI: 10.1038/373607a0.Peer-Reviewed Original ResearchConceptsLeft inferior frontal gyrus regionsInferior frontal gyrus regionsRight inferior frontal gyrusSex differencesInferior frontal gyrusFunctional organizationPattern of activationRight-handed subjectsPhonological processingPhonological tasksSemantic tasksBrain activationFrontal gyrusLanguage functionNeural systemsGyrus regionsCerebral hemispheresTaskLanguageBrainGyrusOrganizationMalesProcessingActivation