1997
Qualitative MR imaging of refractory temporal lobe epilepsy requiring surgery: correlation with pathology and seizure outcome after surgery.
Bronen RA, Fulbright RK, King D, Kim JH, Spencer SS, Spencer DD, Lange RC. Qualitative MR imaging of refractory temporal lobe epilepsy requiring surgery: correlation with pathology and seizure outcome after surgery. American Journal Of Roentgenology 1997, 169: 875-82. PMID: 9275915, DOI: 10.2214/ajr.169.3.9275915.Peer-Reviewed Original ResearchConceptsFebrile seizure historyTemporal lobe epilepsyRefractory temporal lobe epilepsyHippocampal sclerosisSeizure historySeizure outcomeLobe epilepsyHistologic findingsNonspecific gliosisHippocampal atrophyIntractable temporal lobe epilepsyMild hippocampal atrophySimilar clinical conditionsMR imaging diagnosisPositive predictive valueMR imagesSignal intensity changesSegmental findingsNormal findingsClinical parametersNeuronal densityRetrospective studyClinical conditionsSclerosisSurgery
1992
Quantitative magnetic resonance imaging in temporal lobe epilepsy: Relationship to neuropathology and neuropsychological function
Lencz T, McCarthy G, Bronen R, Scott T, Inserni J, Sass K, Novelly R, Kim J, Spencer D. Quantitative magnetic resonance imaging in temporal lobe epilepsy: Relationship to neuropathology and neuropsychological function. Annals Of Neurology 1992, 31: 629-637. PMID: 1514774, DOI: 10.1002/ana.410310610.Peer-Reviewed Original ResearchConceptsControl subjectsLeft temporal lobeTemporal lobeSeizure focusNeuronal densityHippocampal measurementsRight-handed control subjectsMagnetic resonance imagesHippocampal neuronal densityTemporal lobe originEpileptic temporal lobeTemporal lobe epilepsySignificant correlationQuantitative magnetic resonanceRefractory epilepsyLobe epilepsyPatient groupSelective Reminding TestHippocampal ratioLeft hippocampusHippocampal subfieldsPatientsWechsler Memory ScaleNeuropsychological functionHippocampus
1991
Imaging findings in hippocampal sclerosis: correlation with pathology.
Bronen R, Cheung G, Charles J, Kim J, Spencer D, Spencer S, Sze G, McCarthy G. Imaging findings in hippocampal sclerosis: correlation with pathology. American Journal Of Neuroradiology 1991, 12: 933-40. PMID: 1950925, PMCID: PMC8333515.Peer-Reviewed Original ResearchConceptsTemporal lobe epilepsyCryptogenic temporal lobe epilepsyHippocampal sclerosisLobe epilepsyHippocampal atrophyNeuronal densityPathologic criteriaQualitative histologic findingsUnilateral hippocampal atrophyNeuronal cell lossImportant therapeutic consequencesPreoperative radiologic imagingAdjacent white matterLong TR scansGranular cell layerTemporal lobectomyPreoperative diagnosisIntractable epilepsyRadiologic imagingHistologic findingsSurgical specimensCornu ammonisTherapeutic consequencesMR findingsTemporal lobe