2017
Long-term outcomes of tissue-based ACTH-antibody assay-guided transsphenoidal resection of pituitary adenomas in Cushing disease.
Erfe JM, Perry A, McClaskey J, Inzucchi SE, James WS, Eid T, Bronen RA, Mahajan A, Huttner A, Santos F, Spencer D. Long-term outcomes of tissue-based ACTH-antibody assay-guided transsphenoidal resection of pituitary adenomas in Cushing disease. Journal Of Neurosurgery 2017, 129: 629-641. PMID: 29027854, DOI: 10.3171/2017.3.jns162245.Peer-Reviewed Original ResearchConceptsTranssphenoidal resectionMRI studiesCushing's diseaseCortisol levelsLong-term corticosteroid therapyUrinary free cortisol levelsLong-term disease remissionLong-term patient outcomesResults Fourteen patientsLong-term outcomesPostoperative MRI studiesSurgical tumor samplesFree cortisol levelsPreoperative MRI studiesPrecise tumor localizationACTH antibodiesPituitary microCorticosteroid therapyStudy patientsDisease remissionFourteen patientsRemission rateRetrospective reviewTreatment failureCure rate
1993
MR findings after depth electrode implantation for medically refractory epilepsy.
Merriam M, Bronen R, Spencer D, McCarthy G. MR findings after depth electrode implantation for medically refractory epilepsy. American Journal Of Neuroradiology 1993, 14: 1343-6. PMID: 8279329, PMCID: PMC8367502.Peer-Reviewed Original ResearchConceptsDepth electrode implantationProbe tractRefractory epilepsyChronic changesElectrode implantationEvidence of gliosisElectrode placementProbe placementRare complicationDepth electrode placementRetrospective reviewIntraparenchymal hemorrhageSignificant hemorrhageSeizure focusBrain parenchymaSignal abnormalitiesStereotactic placementLower incidenceMR findingsAngiographic dataHemorrhagePatientsDepth electrodesSpin-echo imagesMR scans