2021
17‐a‐estradiol late in life extends lifespan in aging UM‐HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex
Harrison DE, Strong R, Reifsnyder P, Kumar N, Fernandez E, Flurkey K, Javors MA, Lopez‐Cruzan M, Macchiarini F, Nelson JF, Markewych A, Bitto A, Sindler AL, Cortopassi G, Kavanagh K, Leng L, Bucala R, Rosenthal N, Salmon A, Stearns TM, Bogue M, Miller RA. 17‐a‐estradiol late in life extends lifespan in aging UM‐HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex. Aging Cell 2021, 20: e13328. PMID: 33788371, PMCID: PMC8135004, DOI: 10.1111/acel.13328.Peer-Reviewed Original Research
1985
Role of Sex Steroids in Systemic Lupus Erythematosus (SLE)
LAHITA R, BUCALA R, BRADLOW H, FISHMAN J. Role of Sex Steroids in Systemic Lupus Erythematosus (SLE). Protides Of The Biological Fluids 1985, 33: 301-304. DOI: 10.1016/b978-0-08-033215-4.50074-1.Peer-Reviewed Original ResearchSystemic lupus erythematosusPathogenesis of SLESex steroidsHydroxylation of estroneLower plasma androgenActive diseaseLupus erythematosusEstrogen metabolismAlpha-hydroxyestroneOxidation of testosteronePlasma androgensPotent estrogenDiseasePathogenesisSteroidsFemalesMalesMetabolismLow levelsErythematosusPatientsAndrogensEstrogenTestosteroneCell membrane