1999
An inducible gene product for 6-phosphofructo-2-kinase with an AU-rich instability element: Role in tumor cell glycolysis and the Warburg effect
Chesney J, Mitchell R, Benigni F, Bacher M, Spiegel L, Al-Abed Y, Han J, Metz C, Bucala R. An inducible gene product for 6-phosphofructo-2-kinase with an AU-rich instability element: Role in tumor cell glycolysis and the Warburg effect. Proceedings Of The National Academy Of Sciences Of The United States Of America 1999, 96: 3047-3052. PMID: 10077634, PMCID: PMC15892, DOI: 10.1073/pnas.96.6.3047.Peer-Reviewed Original ResearchMeSH Keywords3' Untranslated RegionsAllosteric RegulationAmino Acid SequenceBase SequenceCell DivisionCell Transformation, NeoplasticCloning, MolecularGene Expression Regulation, NeoplasticGlycolysisHumansMolecular Sequence DataNeoplasmsPhosphofructokinase-2Phosphotransferases (Alcohol Group Acceptor)RNA, MessengerSequence AlignmentTumor Cells, CulturedConceptsGene productsWarburg effectAU-rich instability elementsMRNA instability motifsInducible gene productsTissue-specific isoformsImportant control pointPentose phosphate pathwayNucleic acid biosynthesisHigh glycolytic rateAcid biosynthesisInducible genesInstability motifsTumor cell glycolysisAllosteric regulatorsPhosphate pathwayPFK-2Tumor cell growthInstability elementMultiple copiesCell growthCancer cell linesEnhanced glycolysisCell glycolysisHuman cancer cell lines
1996
The Immunoregulatory Mediator Macrophage Migration Inhibitory Factor (MIF) Catalyzes a Tautomerization Reaction
Rosengren E, Bucala R, Åman P, Jacobsson L, Odh G, Metz C, Rorsman H. The Immunoregulatory Mediator Macrophage Migration Inhibitory Factor (MIF) Catalyzes a Tautomerization Reaction. Molecular Medicine 1996, 2: 143-149. PMID: 8900542, PMCID: PMC2230029, DOI: 10.1007/bf03402210.Peer-Reviewed Original Research