1997
Role of Macrophage Migration Inhibitory Factor in the Regulation of the Immune Response
Metz C, Bucala R. Role of Macrophage Migration Inhibitory Factor in the Regulation of the Immune Response. Advances In Immunology 1997, 66: 197-223. PMID: 9328642, DOI: 10.1016/s0065-2776(08)60598-2.Peer-Reviewed Original ResearchConceptsMacrophage migration inhibitory factorMigration inhibitory factorT cellsImmune responseInhibitory factorAnti-inflammatory effectsInflammatory disease statesAnterior pituitary glandSeptic shockMIF actionMIF proteinInflammatory responseGlucocorticoid actionImmune systemPituitary glandCorticotrophic cellsGlucocorticoidsInhibitory effectDisease statesBaseline statePotential roleMacrophagesCellsResponseArthritis
1996
MIF re-discovered: Pituitary hormone and glucocorticoid-induced regulator of cytokine production
Bucala R. MIF re-discovered: Pituitary hormone and glucocorticoid-induced regulator of cytokine production. Cytokine & Growth Factor Reviews 1996, 7: 19-24. PMID: 8864351, DOI: 10.1016/1359-6101(96)00008-1.Peer-Reviewed Original ResearchConceptsMacrophage migration inhibitory factorAssociation of MIFT cell-derived factorsCounter-regulatory hormonesPrimary immune responseMigration inhibitory factorCell-derived factorSource of infectionAnterior pituitary cell lineFirst cytokine activitiesLymph nodesCytokine productionGlucocorticoid actionPituitary cell lineImmune responsePituitary hormonesInflammatory sitesCytokine activityHost responseImmune systemInhibitory factorInhibitory effectTissue invasionProtein mediatorsRandom migration