2017
Estradiol modulates neural response to conspecific and heterospecific song in female house sparrows: An in vivo positron emission tomography study
Lattin CR, Stabile FA, Carson RE. Estradiol modulates neural response to conspecific and heterospecific song in female house sparrows: An in vivo positron emission tomography study. PLOS ONE 2017, 12: e0182875. PMID: 28832614, PMCID: PMC5568339, DOI: 10.1371/journal.pone.0182875.Peer-Reviewed Original ResearchConceptsPositron emission tomographyEmpty implantsNeuronal activityVivo positron emission tomography studiesPositron emission tomography studyBrain glucose metabolismEmission tomography studiesNeural responsesBrain activityNeuronal effectsEstradiol implantsImplant removalHigher estradiolHormone exposureGlucose metabolismBrain regionsEmission tomographyEstradiolTomography studyPET imagingAuditory processingImplantsFemalesAuditory perceptionConspecific song
2003
Brain Uptake of the Acid Metabolites of F-18–Labeled WAY 100635 Analogs
Carson R, Wu Y, Lang L, Ma Y, Der M, Herscovitch P, Eckelman W. Brain Uptake of the Acid Metabolites of F-18–Labeled WAY 100635 Analogs. Cerebrovascular And Brain Metabolism Reviews 2003, 23: 249-260. DOI: 10.1097/00004647-200302000-00012.Peer-Reviewed Original ResearchBrain uptakePositron emission tomography studyArterial blood samplesEmission tomography studiesGray matter parametersPlasma free fractionLow specific bindingTime-activity dataBlood samplesTime-activity curvesAcid metabolitesVascular radioactivityRhesus monkeysTomography studyML/Free fractionTissue compartmentsBrainHuman dataHigh-performance liquid chromatography analysisPhysiologic modelDistribution volume VSpecific bindingDynamic positron emission tomography (PET) studiesLiquid chromatography analysis
2000
PET evaluation of [18F]FCWAY, an analog of the 5-HT1A receptor antagonist, WAY-100635
Carson R, Lang L, Watabe H, Der M, Adams H, Jagoda E, Herscovitch P, Eckelman W. PET evaluation of [18F]FCWAY, an analog of the 5-HT1A receptor antagonist, WAY-100635. Nuclear Medicine And Biology 2000, 27: 493-497. PMID: 10962257, DOI: 10.1016/s0969-8051(00)00118-9.Peer-Reviewed Original Research
1998
Muscarinic Cholinergic Receptor Measurements With [18F]FP-TZTP: Control and Competition Studies
Carson R, Kiesewetter D, Jagoda E, Der M, Herscovitch P, Eckelman W. Muscarinic Cholinergic Receptor Measurements With [18F]FP-TZTP: Control and Competition Studies. Cerebrovascular And Brain Metabolism Reviews 1998, 18: 1130-1142. PMID: 9778190, DOI: 10.1097/00004647-199810000-00010.Peer-Reviewed Original ResearchMeSH KeywordsAcetylcholineAnesthesiaAnesthetics, InhalationAnimalsBinding, CompetitiveBlood ProteinsBrainCholinesterase InhibitorsChromatography, Thin LayerFluorine RadioisotopesIsofluraneKineticsMacaca mulattaModels, NeurologicalPhysostigminePyridinesReceptors, MuscarinicThiazolesTomography, Emission-ComputedConceptsCholinergic receptorsBasal gangliaMuscarinic cholinergic receptorsPositron emission tomography studyM2 cholinergic receptorsMuscarinic cholinergic ligandEmission tomography studiesPositron emission tomographyBrain acetylcholineIntravenous infusionMuscarinic receptorsHigh AChE activityControl studyML xSubcortical regionsAlzheimer's diseaseGray matterCortical regionsEmission tomographyRhesus monkeysArterial input functionTomography studyCholinergic ligandsTracer injectionAChE activity