Caspase-3 Is a Pivotal Mediator of Apoptosis during Regression of the Ovarian Corpus Luteum
Carambula S, Matikainen T, Lynch M, Flavell R, Gonçalves P, Tilly J, Rueda B. Caspase-3 Is a Pivotal Mediator of Apoptosis during Regression of the Ovarian Corpus Luteum. Endocrinology 2002, 143: 1495-1501. DOI: 10.1210/en.143.4.1495.Peer-Reviewed Original ResearchCaspase-3-deficient miceWT miceCorpora luteaCaspase-3Wild-typeLuteal regressionFemale littermatesCaspase-3 enzymePost-ovulationOvarian corpus luteumLevels of progesteroneRate of apoptosisEarly luteal phaseOccurrence of apoptosisAbsence of serumActivated caspase-3Detect activated caspase-3Ex vivo culture experimentsExogenous gonadotropinsNull miceMediators of apoptosisOrgan culture dishesIndividual CLCorpus luteumExecutioners of apoptosis