2022
Ketones: the double-edged sword of SGLT2 inhibitors?
Lupsa BC, Kibbey RG, Inzucchi SE. Ketones: the double-edged sword of SGLT2 inhibitors? Diabetologia 2022, 66: 23-32. PMID: 36255460, DOI: 10.1007/s00125-022-05815-1.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsBlood GlucoseDiabetes Mellitus, Type 2HumansKetonesSodium-Glucose Transporter 2 InhibitorsConceptsSGLT2 inhibitorsDrug categoriesSodium-glucose cotransporter 2 inhibitorsCardio-renal benefitsNormal blood glucose concentrationsCotransporter 2 inhibitorsClasses of medicationsAnti-inflammatory effectsSerious adverse effectsType 1 diabetesBlood glucose levelsBlood glucose concentrationKidney outcomesRare complicationBlood pressureSGLT2 inhibitionGlucose levelsKetone levelsBody weightType 2Ketone bodiesAdverse effectsGlucose concentrationInhibitorsEdged sword
2019
Childhood Pancreatitis and Risk for Incident Diabetes in Adulthood
Bendor CD, Bardugo A, Zucker I, Cukierman-Yaffe T, Lutski M, Derazne E, Shohat T, Mosenzon O, Tzur D, Sapir A, Pinhas-Hamiel O, Kibbey RG, Raz I, Afek A, Gerstein HC, Tirosh A, Twig G. Childhood Pancreatitis and Risk for Incident Diabetes in Adulthood. Diabetes Care 2019, 43: 145-151. PMID: 31694859, PMCID: PMC7011197, DOI: 10.2337/dc19-1562.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdolescentAdultAge of OnsetChildDiabetes Mellitus, Type 2FemaleHumansIncidenceIsraelMalePancreatitisRegistriesRisk FactorsYoung AdultConceptsIsraeli National Diabetes RegistryIncident diabetesAcute pancreatitisNormal pancreatic functionUnexposed groupPancreatic functionOdds ratioChildhood pancreatitisIncident type 2 diabetesNational Diabetes RegistryPopulation-based studyType 2 diabetesDiagnosis of diabetesLogistic regression analysisYears of ageBaseline BMINormal BMIDiabetes RegistryRisk factorsPancreatitisCase subjectsSociodemographic confoundersDiabetesYounger ageFurther adjustment