2021
NIMG-64. TYPE OF BONY INVOLVEMENT PREDICTS GENOMIC SUBGROUP IN SPHENOID WING MENINGIOMAS
Jin L, Youngblood M, Gupte T, Vetsa S, Nadar A, Barak T, Yalcin K, Aguilera S, Mishra-Gorur K, Blondin N, Omay S, Pointdujour-Lim R, Judson B, Alperovich M, Aboian M, McGuone D, Gunel M, Erson-Omay Z, Fulbright R, Moliterno J. NIMG-64. TYPE OF BONY INVOLVEMENT PREDICTS GENOMIC SUBGROUP IN SPHENOID WING MENINGIOMAS. Neuro-Oncology 2021, 23: vi144-vi144. PMCID: PMC8598770, DOI: 10.1093/neuonc/noab196.562.Peer-Reviewed Original ResearchSphenoid wing meningiomaSpheno-orbital meningiomasBony involvementTRAF7 mutationsTumor invasionGenomic subgroupsPre-operative clinical featuresYale-New Haven HospitalAdditional clinical variablesSubset of tumorsPre-operative predictionLogistic regression modelsWhole-exome sequencingClinical featuresClinical variablesGrade IIPredictive logistic regression modelRecurrence patternsMolecular subtypesClinical implicationsExome sequencingHyperostosisMeningiomasTumorsGenomic drivers
2020
LGG-09. CORRELATING GENETIC SIGNATURE OF PILOMYXOID ASTROCYTOMAS AND PILOCYTIC ASTROCYTOMAS WITH QUALITATIVE AND QUANTITATIVE MR IMAGING CHARACTERISTICS
Fadel S, Omay Z, Darbinyan A, Bronen R, Fulbright R, Mahajan A, Aboian M. LGG-09. CORRELATING GENETIC SIGNATURE OF PILOMYXOID ASTROCYTOMAS AND PILOCYTIC ASTROCYTOMAS WITH QUALITATIVE AND QUANTITATIVE MR IMAGING CHARACTERISTICS. Neuro-Oncology 2020, 22: iii367-iii368. PMCID: PMC7715503, DOI: 10.1093/neuonc/noaa222.392.Peer-Reviewed Original ResearchKIAA1549-BRAF fusionBRAF V600E mutationWhole-exome sequencingBRAF-wildtypePilocytic astrocytomaWildtype tumorsV600E mutationImaging characteristicsExome sequencingAtypical imaging featuresMR imaging characteristicsMyxoid featuresPediatric patientsPilomyxoid astrocytomaIntraventricular extensionImaging featuresIntratumoral hemorrhageMRI characteristicsGermline sequencingAtypical featuresT1 intensityTumor localizationWildtype BRAFKIAA1549-BRAFPA correlates