1990
Langerhans cells that migrate to skin after intravenous infusion regulate the induction of contact hypersensitivity.
Cruz P, Tigelaar R, Bergstresser P. Langerhans cells that migrate to skin after intravenous infusion regulate the induction of contact hypersensitivity. The Journal Of Immunology 1990, 144: 2486-92. PMID: 1969448, DOI: 10.4049/jimmunol.144.7.2486.Peer-Reviewed Original ResearchConceptsLow-dose UVB radiationContact hypersensitivityLangerhans cellsIntravenous infusionLow-dose ultraviolet B (UVB) radiationExposure of LCThy-1UVB radiationSuppressor signalsMesenteric lymph nodesLow-dose UVBEffector signalsSkin graft experimentsLC migrationImmunologic targetsLymph nodesAllogeneic transferCH responsesLymphoid tissueImmune responseSyngeneic miceImmunization modelImmunogenic propertiesInfusionUltraviolet B radiation
1988
Local effects of UV radiation on immunization with contact sensitizers. I. Down-regulation of contact hypersensitivity by application of TNCB to UV-irradiated skin.
Cruz P, Nixon-Fulton J, Tigelaar R, Bergstresser P. Local effects of UV radiation on immunization with contact sensitizers. I. Down-regulation of contact hypersensitivity by application of TNCB to UV-irradiated skin. Photodermatology Photoimmunology & Photomedicine 1988, 5: 126-32. PMID: 3174491.Peer-Reviewed Original ResearchConceptsContact hypersensitivityNon-irradiated skinNormal skinApplication of trinitrochlorobenzeneEar-swelling responseUVB-treated miceUV-irradiated skinDaily dosesSuccessful immunizationContact sensitizersC3H miceSite of irradiationFinal exposureTrinitrochlorobenzeneLow dosesAbdominal skinImmunogenic propertiesMiceHypersensitivityImmunizationMouse skinSensitization reactionsDosesSuccessive daysSkin