1990
Langerhans cells that migrate to skin after intravenous infusion regulate the induction of contact hypersensitivity.
Cruz P, Tigelaar R, Bergstresser P. Langerhans cells that migrate to skin after intravenous infusion regulate the induction of contact hypersensitivity. The Journal Of Immunology 1990, 144: 2486-92. PMID: 1969448, DOI: 10.4049/jimmunol.144.7.2486.Peer-Reviewed Original ResearchConceptsLow-dose UVB radiationContact hypersensitivityLangerhans cellsIntravenous infusionLow-dose ultraviolet B (UVB) radiationExposure of LCThy-1UVB radiationSuppressor signalsMesenteric lymph nodesLow-dose UVBEffector signalsSkin graft experimentsLC migrationImmunologic targetsLymph nodesAllogeneic transferCH responsesLymphoid tissueImmune responseSyngeneic miceImmunization modelImmunogenic propertiesInfusionUltraviolet B radiationUVB Radiation and DNFB Skin Painting Induce Suppressor Cells Universally in Mice
Glass M, Bergstresser P, Tigelaar R, Streilein J. UVB Radiation and DNFB Skin Painting Induce Suppressor Cells Universally in Mice. Journal Of Investigative Dermatology 1990, 94: 273-278. PMID: 1689757, DOI: 10.1111/1523-1747.ep12874117.Peer-Reviewed Original ResearchConceptsSuppressor T cellsStrains of miceContact hypersensitivityLangerhans cellsT cellsSuppressor cellsHapten-specific suppressor T cellsInduction of CHSUVB-susceptible strainsT suppressor cellsTreatment of miceAntigen-presenting cellsEpidermal Langerhans cellsEffects of UVBEffector mechanismsMurine skinMiceUVBUVB radiationSkinInductionDinitrofluorobenzeneCellsUVRApparent effect
1988
Thy-1+ Dendritic Epidermal Cells in Mice: Precursor Frequency Analysis and Cloning of Concanavalin A-Reactive Cells
Takashima A, Nixon-Fulton J, Bergstresser P, Tigelaar R. Thy-1+ Dendritic Epidermal Cells in Mice: Precursor Frequency Analysis and Cloning of Concanavalin A-Reactive Cells. Journal Of Investigative Dermatology 1988, 90: 671-678. PMID: 2896217, DOI: 10.1111/1523-1747.ep12560835.Peer-Reviewed Original ResearchConceptsDendritic epidermal cellsPrecursor frequency analysisIL-2Lyt-2Thy-1Con AGrowth factorExogenous IL-2Higher proliferative responsesFunctional activityCytotoxic activityYAC-1Precursor frequencyProliferative responseMouse Thy-1Dilution microculturesLow cytotoxic activityHigh cytotoxic activityTarget cellsLow responsivenessCells/Vivo activityBulk culturesFiller cellsEpidermal cells
1985
FACS Purification of Bone Marrow-Derived Epidermal Populations in Mice: Langerhans Cells and Thy-1+ Dendritic Cells
Sullivan S, Bergstresser P, Tigelaar R, Streilein J. FACS Purification of Bone Marrow-Derived Epidermal Populations in Mice: Langerhans Cells and Thy-1+ Dendritic Cells. Journal Of Investigative Dermatology 1985, 84: 491-495. PMID: 3998496, DOI: 10.1111/1523-1747.ep12273454.Peer-Reviewed Original Research
1976
Specific loss of stimulator activity following mixed lymphocyte reactions is due to cytotoxic cells
Janeway C, Mosier D, Tigelaar R. Specific loss of stimulator activity following mixed lymphocyte reactions is due to cytotoxic cells. European Journal Of Immunology 1976, 6: 747-750. PMID: 138373, DOI: 10.1002/eji.1830061017.Peer-Reviewed Original ResearchConceptsMixed lymphocyte reactionFresh spleen cellsSpleen cellsLymphocyte reactionOne-way mixed-lymphocyte reactionPrimary mixed lymphocyte reactionMouse strainsStimulator activityCytotoxic T cellsStrong mixed lymphocyte reactionsUnrelated mouse strainsCongenic mouse strainsCytotoxic cellsStimulator cellsT cellsRelease assaysSpecific lossCell activityResidual cellsB subregionRestricted expressionLymphocytesSuch cellsAntigenCells
1972
KINETICS OF GRAFT-VERSUS-HOST SPLENOMEGALY IN NEONATAL F1 RECIPIENTS OF PARENTAL STRAIN MOUSE LYMPH NODE CELLS AND/OR THYMOCYTES
Tigelaar R, Asofsky R. KINETICS OF GRAFT-VERSUS-HOST SPLENOMEGALY IN NEONATAL F1 RECIPIENTS OF PARENTAL STRAIN MOUSE LYMPH NODE CELLS AND/OR THYMOCYTES. Transplantation 1972, 14: 805-807. PMID: 4404987, DOI: 10.1097/00007890-197212000-00025.Peer-Reviewed Original ResearchSYNERGY AMONG LYMPHOID CELLS MEDIATING THE GRAFT-VERSUS-HOST RESPONSE
Tigelaar R, Asofsky R. SYNERGY AMONG LYMPHOID CELLS MEDIATING THE GRAFT-VERSUS-HOST RESPONSE. Journal Of Experimental Medicine 1972, 135: 1059-1070. PMID: 4401814, PMCID: PMC2138974, DOI: 10.1084/jem.135.5.1059.Peer-Reviewed Original Research