1994
Diabetes-Induced Alterations in the Properties of Muscarinic Cholinergic Receptors in Rat Vas Deferens
Kamai T, Fukumoto Y, Gousse A, Yoshida M, Davenport T, Weiss R, Latifpour J. Diabetes-Induced Alterations in the Properties of Muscarinic Cholinergic Receptors in Rat Vas Deferens. Journal Of Urology 1994, 152: 1017-1021. PMID: 8051725, DOI: 10.1016/s0022-5347(17)32646-0.Peer-Reviewed Original ResearchConceptsMuscarinic cholinergic receptorsRat vasVas deferensCholinergic receptorsMuscarinic receptorsDiabetic insulin-treated ratsMuscarinic cholinergic receptor subtypesMuscarinic cholinergic receptor densityMembrane particulatesCholinergic receptor densityDiabetes-Induced AlterationsAF-DX 116Cholinergic receptor subtypesMuscarinic cholinergic antagonistAdministration of insulinInsulin-treated ratsAge-matched controlsRat vas deferensRank orderAdditional pharmacological studiesDiabetic ratsBladder domeCerebral cortexCholinergic antagonistsReceptor subtypes
1991
Muscarinic receptors in diabetic rat prostate
Latifpour J, Gousse A, Yoshida M, Weiss R. Muscarinic receptors in diabetic rat prostate. Biochemical Pharmacology 1991, 42: s113-s119. PMID: 1768268, DOI: 10.1016/0006-2952(91)90400-y.Peer-Reviewed Original ResearchConceptsMuscarinic receptorsRat prostateM3 muscarinic receptor subtypesMembrane particulatesAF-DX 116Injection of streptozotocinMuscarinic cholinergic receptorsMuscarinic receptor subtypesSTZ-induced diabetesM3 muscarinic receptorsDiabetic rat prostateLower body weightGroups of ratsInsulin-treated animalsVariety of abnormalitiesDiabetic insulinMuscarinic antagonistSmaller prostatesCholinergic receptorsReceptor subtypesPharmacological profileBody weightFmol/Myo-inositolDiabetes
1989
Effects of experimental diabetes on biochemical and functional characteristics of bladder muscarinic receptors.
Latifpour J, Gousse A, Kondo S, Morita T, Weiss R. Effects of experimental diabetes on biochemical and functional characteristics of bladder muscarinic receptors. Journal Of Pharmacology And Experimental Therapeutics 1989, 248: 81-8. PMID: 2913290.Peer-Reviewed Original ResearchConceptsMuscarinic receptorsBladder domeDiabetic animalsMuscarinic agonistsExperimental diabetesRat bladder smooth muscleED50 valuesHigher serum glucose levelsBladder muscarinic receptorsLarger contractile responsesMuscarinic receptor propertiesAF-DX 116Serum insulin levelsSerum glucose levelsBladder smooth muscleM2 muscarinic receptorsAge-matched controlsLower body weightReceptor binding studiesBladder dysfunctionContractile responseCommon complicationDiabetes mellitusPeripheral neuropathyUrine output