2006
Age Related Changes in the Functional, Biochemical and Molecular Properties of α1-Adrenoceptors in the Rat Genitourinary Tract
Yono M, Foster HE, Weiss RM, Latifpour J. Age Related Changes in the Functional, Biochemical and Molecular Properties of α1-Adrenoceptors in the Rat Genitourinary Tract. Journal Of Urology 2006, 176: 1214-1219. PMID: 16890728, DOI: 10.1016/j.juro.2006.04.038.Peer-Reviewed Original ResearchConceptsRat genitourinary tractLower urinary tract symptomsUrinary tract symptomsBenign prostatic hyperplasiaAdrenoceptor antagonistGenitourinary tractTract symptomsBladder baseProstatic hyperplasiaDorsolateral prostateYoung ratsIsolated muscle bathMaximum contractile responseTranscriptase-polymerase chain reaction techniqueRadioligand receptor bindingReverse transcriptase-polymerase chain reaction techniqueSignificant age-dependent differencesAge-dependent differencesAge related changesHigher body weightAge related differencesContractile responseAdrenoceptor densityAdrenoceptor subtypesBladder dome
1998
CHARACTERIZATION, LOCALIZATION AND DISTRIBUTION OF alpha1 ADRENOCEPTOR SUBTYPE IN MALE RABBIT URETHRA
NISHI K, LATIFPOUR J, SAITO M, FOSTER H, YOSHIDA M, WEISS R. CHARACTERIZATION, LOCALIZATION AND DISTRIBUTION OF alpha1 ADRENOCEPTOR SUBTYPE IN MALE RABBIT URETHRA. Journal Of Urology 1998, 160: 196-205. PMID: 9628650, DOI: 10.1016/s0022-5347(01)63090-8.Peer-Reviewed Original ResearchConceptsAlpha1 adrenoceptorsRabbit urethraMale rabbit urethraSelective alpha1-adrenoceptor antagonistAnti-alpha smooth muscle actinAlpha1-adrenoceptor antagonistRabbit urethral smooth muscleUrethral smooth muscleRadioligand receptor bindingSmooth muscle actinSmooth muscle fibersLight microscopic autoradiographySingle high-affinity binding siteAdrenoceptor antagonistBMY 7378Distal urethraWB 4101Immunohistochemical studyPharmacological characterizationSmooth musclePharmacological profileAdrenoceptorsUrethraMuscle actinHigh-affinity binding sitesCHARACTERIZATION, LOCALIZATION AND DISTRIBUTION OF alpha1 ADRENOCEPTOR SUBTYPE IN MALE RABBIT URETHRA
NISHI K, LATIFPOUR J, SAITO M, FOSTER H, YOSHIDA M, WEISS R. CHARACTERIZATION, LOCALIZATION AND DISTRIBUTION OF alpha1 ADRENOCEPTOR SUBTYPE IN MALE RABBIT URETHRA. Journal Of Urology 1998, 160: 196-205.. DOI: 10.1097/00005392-199807000-00084.Peer-Reviewed Original ResearchAlpha1 adrenoceptorsMale rabbit urethraRabbit urethraSelective alpha1-adrenoceptor antagonistAnti-alpha smooth muscle actinAlpha1-adrenoceptor antagonistRadioligand receptor bindingSmooth muscle actinLight microscopic autoradiographySingle high-affinity binding siteAdrenoceptor antagonistPharmacological profileAbstract PurposeMuscle actinHigh-affinity binding sitesUrethraSubtype specificityAdrenoceptorsAffinity binding sitesReceptor bindingActin antibodyMicroscopic autoradiographySaturation experimentsInhibition experimentsRank order